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  1. Impaired actin–myosin cross-bridge (CB) dynamics correlate with impaired left ventricular (LV) function in early diabetic cardiomyopathy (DCM). Elevated expression and activity of Rho kinase (ROCK) contributes...

    Authors: Mark T Waddingham, Amanda J Edgley, Alberto Astolfo, Tadakatsu Inagaki, Yutaka Fujii, Cheng-Kun Du, Dong-Yun Zhan, Hirotsugu Tsuchimochi, Naoto Yagi, Darren J Kelly, Mikiyasu Shirai and James T Pearson
    Citation: Cardiovascular Diabetology 2015 14:92
  2. Insulin-induced microvascular recruitment is important for optimal muscle glucose uptake. 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR, an activator of AMP-activated protein kinase), can also induce...

    Authors: Eloise A Bradley, Lei Zhang, Amanda J Genders, Stephen M Richards, Stephen Rattigan and Michelle A Keske
    Citation: Cardiovascular Diabetology 2015 14:91
  3. Oxidative stress plays a major role in diabetic cardiomyopathy pathogenesis. Anti-oxidant therapy has been investigated in preventing or treating several diabetic complications. However, anti-oxidant action on...

    Authors: Julliano F C Guimaraes, Bruno P Muzio, Camila M Rosa, Andre F Nascimento, Mario M Sugizaki, Ana A H Fernandes, Antonio C Cicogna, Carlos R Padovani, Marina P Okoshi and Katashi Okoshi
    Citation: Cardiovascular Diabetology 2015 14:90
  4. Skin autofluorescence is a non-invasive measurement of advanced glycation end products (AGE), which are suggested to be one of the major agents in the pathogenesis and progression of diabetes related cardiovas...

    Authors: Y H M Krul-Poel, R Agca, P Lips, H van Wijland, F Stam and S Simsek
    Citation: Cardiovascular Diabetology 2015 14:89
  5. It is uncertain whether non-alcoholic fatty liver disease (NAFLD) or abdominal obesity is more associated with atherosclerosis. The aim of this study was to determine whether NAFLD or abdominal obesity is more...

    Authors: Min-Kyung Lee, Hye-Jeong Park, Won Seon Jeon, Se Eun Park, Cheol-Young Park, Won-Young Lee, Ki-Won Oh, Sung-Woo Park and Eun-Jung Rhee
    Citation: Cardiovascular Diabetology 2015 14:88
  6. Type 2 diabetes is associated with abnormal electrical conduction and sudden cardiac death, but the pathogenic mechanism remains unknown. This study describes electrophysiological alterations in a diet-induced...

    Authors: Lene Nygaard Axelsen, Kirstine Calloe, Thomas Hartig Braunstein, Mads Riemann, Johannes Pauli Hofgaard, Bo Liang, Christa Funch Jensen, Kristine Boisen Olsen, Emil D. Bartels, Ulrik Baandrup, Thomas Jespersen, Lars Bo Nielsen, Niels-Henrik Holstein-Rathlou and Morten Schak Nielsen
    Citation: Cardiovascular Diabetology 2015 14:87
  7. Strokes are commonly preceded by transient ischemic attacks (TIAs). TIA is often associated with metabolic syndrome (causing chronic inflammation), resulting in a proinflammatory- and procoagulant-environment....

    Authors: Mia-Jeanne van Rooy, Wiebren Duim, Rene Ehlers, Antoinette V. Buys and Etheresia Pretorius
    Citation: Cardiovascular Diabetology 2015 14:86
  8. Diabetic patients have an increased risk of developing cardiovascular diseases, which are the leading cause of death in developed countries. Although multivitamin products are widely used as dietary supplement...

    Authors: Márta Sárközy, Gergő Szűcs, Márton Pipicz, Ágnes Zvara, Katalin Éder, Veronika Fekete, Csilla Szűcs, Judit Bárkányi, Csaba Csonka, László G. Puskás, Csaba Kónya, Péter Ferdinandy and Tamás Csont
    Citation: Cardiovascular Diabetology 2015 14:85
  9. It is not clear which glucose measure is more useful in the assessment of atherosclerosis. We investigated the associations of hemoglobin A1c (HbA1c), glycated albumin (GA), 1,5-anhydroglucitol (1,5-AG), fasting ...

    Authors: Naoko Mukai, Toshiharu Ninomiya, Jun Hata, Yoichiro Hirakawa, Fumie Ikeda, Masayo Fukuhara, Taeko Hotta, Masafumi Koga, Udai Nakamura, Dongchon Kang, Takanari Kitazono and Yutaka Kiyohara
    Citation: Cardiovascular Diabetology 2015 14:84
  10. Left ventricular (LV) diastolic dysfunction is frequently observed in patients with type 2 diabetes. Dipeptidyl peptidase-4 inhibitor (DPP-4i) attenuates postprandial hyperglycemia (PPH) and may have cardio-pr...

    Authors: Hiroki Oe, Kazufumi Nakamura, Hajime Kihara, Kenei Shimada, Shota Fukuda, Tsutomu Takagi, Toru Miyoshi, Kumiko Hirata, Junichi Yoshikawa and Hiroshi Ito
    Citation: Cardiovascular Diabetology 2015 14:83
  11. The relationship between osteocalcin and atherosclerosis remains unclear. This might be due to different degrees of confounding from factors that are associated with serum osteocalcin level, such as metabolic-...

    Authors: Yuqi Luo, Xiaojing Ma, Yaping Hao, Qin Xiong, Yiting Xu, Xiaoping Pan, Yuqian Bao and Weiping Jia
    Citation: Cardiovascular Diabetology 2015 14:82
  12. Factor Xa inhibitor is used for preventing venous thromboembolism (VTE) in adult patients receiving orthopedic operation. However, the role of factor Xa inhibitor, rivaroxaban, in angiogenesis is still unknown.

    Authors: Tao-Cheng Wu, Jenq-Shyong Chan, Chiu-Yang Lee, Hsin-Bang Leu, Po-Hsun Huang, Jia-Shiong Chen, Shing-Jong Lin and Jaw-Wen Chen
    Citation: Cardiovascular Diabetology 2015 14:81
  13. Patients with type 2 diabetes mellitus (DM) display a predisposition for vascular disease. Platelets taken from vasculopathic diabetic patients, show enhanced stimuli-induced activation and aggregation respons...

    Authors: Gadi Shlomai, Tal Haran-Appel, Tal Sella, Yoni Grossman, Hagit Hauschner, Nurit Rosenberg and Ehud Grossman
    Citation: Cardiovascular Diabetology 2015 14:80
  14. As a first-line diabetes drug that is widely prescribed around the world, metformin has been demonstrated to be effective in reducing microvascular risk, in addition to lowering glucose levels. Specifically, m...

    Authors: Chao Zhang, Feng Gao, Hao Luo, Chun-Ting Zhang and Ren Zhang
    Citation: Cardiovascular Diabetology 2015 14:79
  15. Glucose fluctuation has been recognized as a residual risk apart from dyslipidemia for the development of coronary artery disease (CAD). This study aimed to investigate the association between glucose fluctuat...

    Authors: Masaru Kuroda, Toshiro Shinke, Kazuhiko Sakaguchi, Hiromasa Otake, Tomofumi Takaya, Yushi Hirota, Tsuyoshi Osue, Hiroto Kinutani, Akihide Konishi, Hachidai Takahashi, Daisuke Terashita, Kenzo Uzu and Ken-ichi Hirata
    Citation: Cardiovascular Diabetology 2015 14:78
  16. Fibroblast growth factor 21 (FGF21) is an important regulator in glucose and lipid metabolism, and has been considered as a potential therapy for diabetes. The effect of FGF21 on the development and progressio...

    Authors: Xiaoqing Yan, Jun Chen, Chi Zhang, Jun Zeng, Shanshan Zhou, Zhiguo Zhang, Xuemian Lu, Jing Chen, Wenke Feng, Xiaokun Li and Yi Tan
    Citation: Cardiovascular Diabetology 2015 14:77
  17. Both angiotensin II type 1 receptor (AT1R) and nuclear factor-kappa B (NF-κB) play significant roles in the pathogenesis of hypertension and type 2 diabetes. However, the role of NF-κB in perpetuating renal AT1 r...

    Authors: Hao Luo, Xinquan Wang, Jialiang Wang, Caiyu Chen, Na Wang, Zaicheng Xu, Shuo Chen and Chunyu Zeng
    Citation: Cardiovascular Diabetology 2015 14:76
  18. Several translational studies have identified the differential role between saturated and unsaturated fatty acids at cardiovascular level. However, the molecular mechanisms that support the protective role of ...

    Authors: Liliana Perdomo, Nuria Beneit, Yolanda F. Otero, Óscar Escribano, Sabela Díaz-Castroverde, Almudena Gómez-Hernández and Manuel Benito
    Citation: Cardiovascular Diabetology 2015 14:75
  19. There are few studies that investigated the correlation between insulin resistance (IR) and the coronary artery remodeling. The aim of the study is to investigate the association of IR measured by homeostasis ...

    Authors: Sang-Hoon Kim, Jae-Youn Moon, Yeong Min Lim, Kyung Ho Kim, Woo-In Yang, Jung-Hoon Sung, Seung Min Yoo, In Jai Kim, Sang-Wook Lim, Dong-Hun Cha and Seung-Yun Cho
    Citation: Cardiovascular Diabetology 2015 14:74
  20. Fibroblast growth factor 21 (FGF21), a glucose and lipid metabolic regulator, has recently been demonstrated to be associated with cardiovascular diseases (CVD) such as carotid atherosclerosis, coronary heart ...

    Authors: Yang Xiao, Lingjiao Liu, Aimin Xu, Pengcheng Zhou, Zhaofeng Long, Yiting Tu, Xiaoyan Chen, Weili Tang, Gan Huang and Zhiguang Zhou
    Citation: Cardiovascular Diabetology 2015 14:72
  21. Type 1 diabetes is associated with raised inflammation, impaired endothelial progenitor cell mobilisation and increased markers of vascular injury. Both acute and chronic exercise is known to influence these m...

    Authors: Daniel J West, Matthew D Campbell, Javier T Gonzalez, Mark Walker, Emma J Stevenson, Fahad W Ahmed, Stephanie Wijaya, James A Shaw and Jolanta U Weaver
    Citation: Cardiovascular Diabetology 2015 14:71
  22. It is presently unclear whether glycemic variability is associated with diabetic cardiovascular autonomic neuropathy (CAN). The aim of this study was to examine whether short- and/or long-term glycemic variabi...

    Authors: Ji Eun Jun, Sang-Man Jin, Jongha Baek, Sewon Oh, Kyu Yeon Hur, Myung-Shik Lee, Moon-Kyu Lee and Jae Hyeon Kim
    Citation: Cardiovascular Diabetology 2015 14:70
  23. Fatty acid (FA) catabolism abnormality has been proved to play an important role in obesity-related cardiomyopathy. We hypothesized that cardiospecific suppression of CD36, the predominant membrane FA transpor...

    Authors: Yijie Zhang, Mingwei Bao, Mingyan Dai, Xin Wang, Wenbo He, Tuantuan Tan, Dandan Lin, Wei Wang, Ying Wen and Rui Zhang
    Citation: Cardiovascular Diabetology 2015 14:69
  24. The influence of diabetes mellitus (DM) on platelet reactivity (PR) in prasugrel or ticagrelor treated patients is not well studied.

    Authors: Dimitrios Alexopoulos, Chrysoula Vogiatzi, Katerina Stavrou, Niki Vlassopoulou, Angelos Perperis, Ioanna Pentara and Ioanna Xanthopoulou
    Citation: Cardiovascular Diabetology 2015 14:68
  25. Low circulating levels of total vitamin D [25(OH)D] and 25(OH)D3 have been associated with vascular complications in few studies on individuals with type 1 diabetes. However, these measures are affected by UV lig...

    Authors: Lian Engelen, Casper G. Schalkwijk, Simone J. P. M. Eussen, Jean L. J. M. Scheijen, Sabita S. Soedamah-Muthu, Nish Chaturvedi, John H. Fuller and Coen D. A. Stehouwer
    Citation: Cardiovascular Diabetology 2015 14:67
  26. The influence of diabetes mellitus on myocardial ischemic preconditioning is not clearly defined. Experimental studies are conflicting and human studies are scarce and inconclusive.

    Authors: Paulo Cury Rezende, Rosa Maria Rahmi, Augusto Hiroshi Uchida, Leandro Menezes Alves da Costa, Thiago Luis Scudeler, Cibele Larrosa Garzillo, Eduardo Gomes Lima, Carlos Alexandre Wainrober Segre, Priscyla Girardi, Myrthes Takiuti, Marcela Francisca Silva, Whady Hueb, Jose Antonio Franchini Ramires and Roberto Kalil Filho
    Citation: Cardiovascular Diabetology 2015 14:66
  27. Authors: Jerzy Kotlinowski, Anna Grochot-Przeczek, Hevidar Taha, Magdalena Kozakowska, Bartosz Pilecki, Klaudia Skrzypek, Jakub Zimoch, Aleksandra Bartelik, Rafal Derlacz, Anton J G Horrevoets, Attila Pap, Laszlo Nagy, Jozef Dulak and Alicja Jozkowicz
    Citation: Cardiovascular Diabetology 2015 14:65

    The original article was published in Cardiovascular Diabetology 2014 13:150

  28. Although Bone morphogenetic protein-2 (BMP-2) is a known mediator of bone regeneration and vascular calcification, to date no study has investigated the relationship between BMP-2 and type 2 diabetes mellitus ...

    Authors: Ming Zhang, Jaskanwal Deep Sara, Fei-long Wang, Li-Ping Liu, Li-Xiao Su, Jing Zhe, Xi Wu and Jing-hua Liu
    Citation: Cardiovascular Diabetology 2015 14:64
  29. Hypertension (EH) and type 2 diabetes (T2DM) are major causes of chronic kidney disease (CKD) and identification of predictors of CKD onset is advisable. We aimed to assess whether dynamic renal resistive inde...

    Authors: R. M. Bruno, A. Salvati, M. Barzacchi, K. Raimo, S. Taddei, L. Ghiadoni and A. Solini
    Citation: Cardiovascular Diabetology 2015 14:63
  30. New and clinically useful markers of cardiovascular risk are of essence in type 2 diabetes since ischemic heart disease is a major cause of death in these patients.

    Authors: Camilla Vavruch, Toste Länne, Mats Fredrikson, Torbjörn Lindström, Carl Johan Östgren and Fredrik H Nystrom
    Citation: Cardiovascular Diabetology 2015 14:62
  31. Type-2 diabetes is associated with systemic inflammation and higher C-reactive protein (CRP) levels. However, the longitudinal association of CRP and haemoglobin-A1c (HbA1c) has not been described in large prospe...

    Authors: Sara Ahmadi-Abhari, Stephen Kaptoge, Robert N Luben, Nicholas J Wareham and Kay-Tee Khaw
    Citation: Cardiovascular Diabetology 2015 14:61
  32. Diabetes is a major cardiovascular risk factor. However, its influence on the rate of occurrence of cardiovascular (CV) events during a clinical trial that included a diabetes subgroup has not yet been quantif...

    Authors: Michel P. Hermans, Evariste Bouenizabila, Daniel K. Amoussou-guenou, Sylvie A. Ahn and Michel F. Rousseau
    Citation: Cardiovascular Diabetology 2015 14:60
  33. In patients with type 2 diabetes, cardiovascular disease (CVD) is the major cause of morbidity and mortality. We evaluated the combination of NT-proBNP and coronary artery calcium score (CAC) for prediction of...

    Authors: Bernt Johan von Scholten, Henrik Reinhard, Tine Willum Hansen, Morten Lindhardt, Claus Leth Petersen, Niels Wiinberg, Peter Riis Hansen, Hans-Henrik Parving, Peter Karl Jacobsen and Peter Rossing
    Citation: Cardiovascular Diabetology 2015 14:59
  34. Subjects with normal body mass index (BMI) but elevated amounts of body fat (normal-weight obesity; NWO) show cardiometabolic dysregulation compared to subjects with normal BMI and normal amounts of body fat (...

    Authors: Sohee Kim, Chanhee Kyung, Jong Suk Park, Seung-Pyo Lee, Hye Kyoung Kim, Chul Woo Ahn, Kyung Rae Kim and Shinae Kang
    Citation: Cardiovascular Diabetology 2015 14:58
  35. The cardiovascular (CV) safety of linagliptin was evaluated in subjects with type 2 diabetes (T2DM).

    Authors: Julio Rosenstock, Nikolaus Marx, Dietmar Neubacher, Thomas Seck, Sanjay Patel, Hans-Juergen Woerle and Odd Erik Johansen
    Citation: Cardiovascular Diabetology 2015 14:57
  36. Endotoxin (i.e. LPS) administration induces a robust inflammatory response with accompanying cardiovascular dysfunction and insulin resistance. Overabundance of nitric oxide (NO) contributes to the vascular dy...

    Authors: Lawrence M. House II, Robert T. Morris, Tammy M. Barnes, Louise Lantier, Travis J. Cyphert, Owen P. McGuinness and Yolanda F. Otero
    Citation: Cardiovascular Diabetology 2015 14:56
  37. Non alcoholic fatty liver disease (NAFLD) is an independent cardiovascular (CV) risk factor which is closely associated with insulin resistance measured by both direct or indirect methods. Gender specific find...

    Authors: Barbara Buday, Peter Ferenc Pach, Botond Literati-Nagy, Marta Vitai, Gyorgyi Kovacs, Zsuzsa Vecsei, Laszlo Koranyi and Csaba Lengyel
    Citation: Cardiovascular Diabetology 2015 14:55
  38. It is unclear whether dipeptidylpeptidase-4 (DPP-4) inhibition can counteract the impairment of cognitive function and brain injury caused by transient cerebral ischemia in type 2 diabetes. The present study w...

    Authors: MingJie Ma, Yu Hasegawa, Nobutaka Koibuchi, Kensuke Toyama, Ken Uekawa, Takashi Nakagawa, Bowen Lin and Shokei Kim-Mitsuyama
    Citation: Cardiovascular Diabetology 2015 14:54
  39. We investigated the relationship between the glycemic indices glycated albumin (GA) and glycated hemoglobin (HbA1c) and the progression of diabetic vascular complications [diabetic nephropathy (DN) and carotid ar...

    Authors: Hye-jin Yoon, Yong-ho Lee, So Ra Kim, Tyler Hyungtaek Rim, Eun Young Lee, Eun Seok Kang, Bong-Soo Cha, Hyun Chul Lee and Byung-Wan Lee
    Citation: Cardiovascular Diabetology 2015 14:53
  40. To investigate whether apolipoprotein A (apoA)-I glycation and paraoxonase (PON) activities are associated with the severity of coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM).

    Authors: Ying Shen, Feng Hua Ding, Jia Teng Sun, Li Jin Pu, Rui Yan Zhang, Qi Zhang, Qiu Jing Chen, Wei Feng Shen and Lin Lu
    Citation: Cardiovascular Diabetology 2015 14:52
  41. Vascular function is impaired in patients with diabetes, however diabetic vascular dysfunction is ameliorated by exercise training. We aimed to clarify which hindlimb arterial segments are affected by treadmil...

    Authors: Takashi Sonobe, Hirotsugu Tsuchimochi, Daryl O. Schwenke, James T. Pearson and Mikiyasu Shirai
    Citation: Cardiovascular Diabetology 2015 14:51
  42. The complement component C1q triggers activation of the classical immune pathway and can bind to adiponectin (APN). Recently, some studies have been reported that serum C1q-APN/total APN ratio correlates with ...

    Authors: Eun Shil Hong, Cheong Lim, Hye Yeon Choi, Eu Jeong Ku, Kyoung Min Kim, Jae Hoon Moon, Soo Lim, Kyong Soo Park, Hak Chul Jang and Sung Hee Choi
    Citation: Cardiovascular Diabetology 2015 14:50
  43. We investigated the clinical relevance of a common variant, rs4820599, in the γ-glutamyltransferase (GGT)1 gene, associated with the serum GGT level, in Japanese type 2 diabetes mellitus (T2DM) subjects.

    Authors: Hideaki Jinnouchi, Kazunori Morita, Takahiro Tanaka, Ayami Kajiwara, Yuki Kawata, Kentaro Oniki, Junji Saruwatari, Kazuko Nakagawa, Koji Otake, Yasuhiro Ogata, Akira Yoshida, Seiji Hokimoto and Hisao Ogawa
    Citation: Cardiovascular Diabetology 2015 14:49
  44. This study aims to describe trends in the rate of abdominal aortic aneurysm (AAA) and use of open surgery repair (OSR) and endovascular aneurysm repair (EVAR) in elderly patients with and without type 2 diabet...

    Authors: Ana Lopez-de-Andrés, Isabel Jiménez-Trujillo, Rodrigo Jiménez-García, Valentín Hernández-Barrera, José Mª de Miguel-Yanes, Manuel Méndez-Bailón, Napoleón Perez-Farinos, Miguel Ángel Salinero-Fort and Pilar Carrasco-Garrido
    Citation: Cardiovascular Diabetology 2015 14:48

    The Erratum to this article has been published in Cardiovascular Diabetology 2016 15:103

  45. Subclinical left ventricular (LV) longitudinal myocardial systolic dysfunction occurs in patients with diabetes mellitus (DM) and preserved LV ejection fraction (LVEF), and is closely related to DM-related com...

    Authors: Yasuhide Mochizuki, Hidekazu Tanaka, Kensuke Matsumoto, Hiroyuki Sano, Hiromi Toki, Hiroyuki Shimoura, Junichi Ooka, Takuma Sawa, Yoshiki Motoji, Keiko Ryo, Yushi Hirota, Wataru Ogawa and Ken-ichi Hirata
    Citation: Cardiovascular Diabetology 2015 14:47
  46. Visceral fat, including epicardial fat (EF) is recognized as a responsible factor of cardiovascular disease. The aim of this study was to investigate the relationship between EF and diabetes in Korean men.

    Authors: Hyejin Chun, Eunkyung Suh, A Ri Byun, Hae Ran Park and Kyung Won Shim
    Citation: Cardiovascular Diabetology 2015 14:46
  47. We have previously shown that in hypertensive Dahl salt-sensitive (DS) rats, impaired endothelium-dependent relaxation to acetylcholine and to insulin is mechanistically linked to up-regulation of angiotensin ...

    Authors: Ming-Sheng Zhou, Chang Liu, Runxia Tian, Akira Nishiyama and Leopoldo Raij
    Citation: Cardiovascular Diabetology 2015 14:45
  48. To investigate the effect of low blood glucose on thrombin generation and fibrin clot properties in type 2 diabetes (T2DM).

    Authors: Grzegorz Gajos, Malgorzata Konieczynska, Jaroslaw Zalewski and Anetta Undas
    Citation: Cardiovascular Diabetology 2015 14:44
  49. Left ventricular hypertrophy (LVH) is prevalent in patients with type 2 diabetes mellitus (T2DM). Recent studies show that an increase in albumin-adjusted serum calcium level is associated with an elevated ris...

    Authors: Junfeng Li, Nan Wu, Yintao Li, Kuanping Ye, Min He and Renming Hu
    Citation: Cardiovascular Diabetology 2015 14:43

Cardiovascular Diabetology is affiliated with Sackler Faculty of Medicine, Tel-Aviv University

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