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  1. Glucagon-like peptide-1 (GLP-1) therapies are routinely used for glycaemic control in diabetes and their emerging cardiovascular actions have been a major recent research focus. In addition to GLP-1 receptor a...

    Authors: Emma Robinson, Mitchel Tate, Samuel Lockhart, Claire McPeake, Karla M. O’Neill, Kevin S. Edgar, Danielle Calderwood, Brian D. Green, Barbara J. McDermott and David J. Grieve
    Citation: Cardiovascular Diabetology 2016 15:65
  2. Whole body dual-energy X-ray absorptiometry (DXA) can simultaneously measure both regional fat and non-fat mass. Android-to-gynoid (A/G) ratio measured by DXA has been reported to be associated with cardiovasc...

    Authors: Ryotaro Bouchi, Yujiro Nakano, Norihiko Ohara, Takato Takeuchi, Masanori Murakami, Masahiro Asakawa, Yuriko Sasahara, Mitsuyuki Numasawa, Isao Minami, Hajime Izumiyama, Koshi Hashimoto, Takanobu Yoshimoto and Yoshihiro Ogawa
    Citation: Cardiovascular Diabetology 2016 15:64
  3. Vascular dysfunction is a distinctive phenotype in diabetes mellitus. Current treatments mostly focus on the tight glycemic control and few of these treatments have been designed to directly recover the vascul...

    Authors: Yu-Guang Ma, Yin-Bin Zhang, Yun-Gang Bai, Zhi-Jun Dai, Liang Liang, Mei Liu, Man-Jiang Xie and Hai-Tao Guan
    Citation: Cardiovascular Diabetology 2016 15:63
  4. Diabetic patients suffer from undesired intimal hyperplasia after angioplasty. Nicorandil has a trend to reduce the rate of target lesion revascularization. However, whether nicorandil inhibits intimal hyperpl...

    Authors: Ying Qian Zhang, Feng Tian, Ying Zhou, Yun Dai Chen, Bo Li, Qiang Ma and Ying Zhang
    Citation: Cardiovascular Diabetology 2016 15:62
  5. Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor ß family and has been associated with inflammation, cancer, aging, diabetes mellitus (DM) and atherosclerosis. Determinan...

    Authors: Serdar Farhan, Matthias K. Freynhofer, Ivan Brozovic, Veronika Bruno, Birgit Vogel, Ioannis Tentzeris, Sabina Baumgartner-Parzer, Kurt Huber and Alexandra Kautzky-Willer
    Citation: Cardiovascular Diabetology 2016 15:60
  6. The German Diabetes Study (GDS) is a prospective longitudinal cohort study describing the impact of subphenotypes on the course of the disease. GDS aims at identifying prognostic factors and mechanisms underly...

    Authors: Julia Szendroedi, Aaruni Saxena, Katharina S. Weber, Klaus Strassburger, Christian Herder, Volker Burkart, Bettina Nowotny, Andrea Icks, Oliver Kuss, Dan Ziegler, Hadi Al-Hasani, Karsten Müssig and Michael Roden
    Citation: Cardiovascular Diabetology 2016 15:59
  7. Whether body composition is associated with the N-terminal pro-B-type natriuretic peptide (NT-proBNP) level and its prognostic performance in acute coronary syndrome (ACS) remains unknown. We aimed to investig...

    Authors: Fang-Yang Huang, Hua Wang, Bao-Tao Huang, Wei Liu, Yong Peng, Chen Zhang, Tian-Li Xia, Peng-Ju Wang, Zhi-Liang Zuo, Yue Heng, Rui-Shuang Liu, Xiao-Bo Pu, Yi-Yue Gui, Shi-Jian Chen, Ye Zhu and Mao Chen
    Citation: Cardiovascular Diabetology 2016 15:58
  8. Low socioeconomic status (SES) is associated with adverse cardiovascular risk factor patterns and poor outcomes in patients with diabetes. The aim of this study was to determine whether SES is associated with ...

    Authors: Xiaoming Tao, Jihu Li, Xiaolin Zhu, Bin Zhao, Jiao Sun, Linong Ji, Dayi Hu, Changyu Pan, Yuxin Huang, Suyuan Jiang, Qiang Feng and Cuiping Jiang
    Citation: Cardiovascular Diabetology 2016 15:61
  9. Because type 2 diabetes mellitus is associated strongly with an increased risk of cardiovascular diseases, the number of patients with diabetes with chronic heart failure is increasing steadily. However, clini...

    Authors: Atsushi Tanaka, Teruo Inoue, Masafumi Kitakaze, Jun-ichi Oyama, Masataka Sata, Isao Taguchi, Wataru Shimizu, Hirotaka Watada, Hirofumi Tomiyama, Junya Ako, Yasushi Sakata, Toshihisa Anzai, Masaaki Uematsu, Makoto Suzuki, Kazuo Eguchi, Akira Yamashina…
    Citation: Cardiovascular Diabetology 2016 15:57
  10. Contemporary guidelines recommend angiotensin-converting-enzyme inhibitors (ACEi) or angiotensin-receptor blockers (ARB) for hypertensive patients with diabetes. However, there is limited data to evaluate the ...

    Authors: Lung-Sheng Wu, Shang-Hung Chang, Gwo-Jyh Chang, Jia-Rou Liu, Yi-Hsin Chan, Hsin-Fu Lee, Ming-Shien Wen, Wei-Jan Chen, Yung-Hsin Yeh, Chi-Tai Kuo and Lai-Chu See
    Citation: Cardiovascular Diabetology 2016 15:56
  11. Gliptins should have beneficial effects beyond glycemic control, potentially on the pathophysiology of cardiovascular (CV) diseases, with some basic studies demonstrating this possibility. However, we are yet ...

    Authors: Takashi Nakamura, Yoshitaka Iwanaga, Yuki Miyaji, Ryuji Nohara, Takao Ishimura and Shunichi Miyazaki
    Citation: Cardiovascular Diabetology 2016 15:54
  12. Prior studies demonstrate mitochondrial dysfunction with increased reactive oxygen species generation in peripheral blood mononuclear cells in diabetes mellitus. Oxidative stress-mediated damage to mitochondri...

    Authors: Jessica L. Fetterman, Monica Holbrook, David G. Westbrook, Jamelle A. Brown, Kyle P. Feeley, Rosa Bretón-Romero, Erika A. Linder, Brittany D. Berk, Robert M. Weisbrod, Michael E. Widlansky, Noyan Gokce, Scott W. Ballinger and Naomi M. Hamburg
    Citation: Cardiovascular Diabetology 2016 15:53
  13. The function of platelets have extended way beyond the horizon of haemostasis and thrombosis, and are recognised as active participants in vascular inflammation, as well as in prothrombotic complications of ca...

    Authors: Prashilla Soma, Albe Carina Swanepoel, Jeanette Noel du Plooy, Thandi Mqoco and Etheresia Pretorius
    Citation: Cardiovascular Diabetology 2016 15:52
  14. Oxidative stress, inflammation and endothelial dysfunction are interrelated factors in the etiology of cardiovascular disease, but their linkage to type 2 diabetes is less clear. We examined the association of...

    Authors: Andrew O. Odegaard, David R. Jacobs Jr., Otto A. Sanchez, David C. Goff Jr., Alexander P. Reiner and Myron D. Gross
    Citation: Cardiovascular Diabetology 2016 15:51
  15. The mechanisms leading to the high on-treatment platelet reactivity in diabetes patients are not fully elucidated. The genetic factors may be associated with the diminished antiplatelet efficacy of dual antipl...

    Authors: Dingyu Zhang, Xiaolin Zhang, Dan Liu, Tengfei Liu, Wenzhi Cai, Chenghui Yan and Yaling Han
    Citation: Cardiovascular Diabetology 2016 15:50
  16. Circulating microRNAs (miRs) are differentially regulated and selectively packaged into microparticles (MPs). We evaluated whether diabetes mellitus alters circulating vascular and endothelial MP-incorporated ...

    Authors: Felix Jansen, Han Wang, David Przybilla, Bernardo S. Franklin, Andreas Dolf, Philipp Pfeifer, Theresa Schmitz, Anna Flender, Elmar Endl, Georg Nickenig and Nikos Werner
    Citation: Cardiovascular Diabetology 2016 15:49
  17. Heart failure (HF), especially with preserved ejection fraction (HFpEF) is common in older patients with type 2 diabetes (T2DM), but often not recognized. Early HF detection in older T2DM patients may be worth...

    Authors: Anoukh van Giessen, Leandra J. M. Boonman-de Winter, Frans H. Rutten, Maarten J. Cramer, Marcel J. Landman, Anho H. Liem, Arno W. Hoes and Hendrik Koffijberg
    Citation: Cardiovascular Diabetology 2016 15:48
  18. Questions remain as to the association between essential hypertension and increased incidence of type 2 diabetes (T2DM). The premise of this analysis is that insulin resistance/compensatory hyperinsulinemia is...

    Authors: Ki-Chul Sung, Hyun-Young Park, Min-Ju Kim and Gerald Reaven
    Citation: Cardiovascular Diabetology 2016 15:47
  19. Hyperglycemia and increased levels of methylglyoxal (MGO) can trigger the development of vascular complications in diabetes. Resveratrol and quercetin are red wine polyphenols with known beneficial cardiovascu...

    Authors: Charlotte Boydens, Bart Pauwels, Laura Vanden Daele and Johan Van de Voorde
    Citation: Cardiovascular Diabetology 2016 15:46
  20. Reduced heart rate variability (HRV), a measure of cardiac autonomic function, is associated with an increased risk of cardiovascular disease (CVD) and mortality. Glucose homeostasis measures are associated wi...

    Authors: Michelle L. Meyer, Nathan M. Gotman, Elsayed Z. Soliman, Eric A. Whitsel, Raanan Arens, Jianwen Cai, Martha L. Daviglus, Pablo Denes, Hector M. González, Juan Moreiras, Gregory A. Talavera and Gerardo Heiss
    Citation: Cardiovascular Diabetology 2016 15:45
  21. Diabetic cardiomyopathy (DCM) is a disorder of the heart muscle in people with diabetes that can occur independent of hypertension or vascular disease. The underlying mechanism of DCM is incompletely understoo...

    Authors: Vidya Kandula, Ramoji Kosuru, Haobo Li, Dan Yan, Qiqi Zhu, Qingquan Lian, Ren-shan Ge, Zhengyuan Xia and Michael G. Irwin
    Citation: Cardiovascular Diabetology 2016 15:44
  22. Both carotid and lower limb atherosclerosis are associated with increased cardiovascular and cerebrovascular risks. However, it is still unclear whether the concomitant presence of carotid and lower extremity ...

    Authors: Mei-Fang Li, Cui-Chun Zhao, Ting-Ting Li, Yin-Fang Tu, Jun-Xi Lu, Rong Zhang, Ming-Yun Chen, Yu-Qian Bao, Lian-Xi Li and Wei-Ping Jia
    Citation: Cardiovascular Diabetology 2016 15:43
  23. Previous studies have shown that high glucose (HG) induced endothelial cell (EC) damage via a phenotypic transition of EC. There is increasing evidence suggesting the role of inflammatory cytokines in mediated...

    Authors: Dong-Dong Zhu, Ri-Ning Tang, Lin-Li Lv, Yi Wen, Hong Liu, Xiao-Liang Zhang, Kun-Ling Ma and Bi-Cheng Liu
    Citation: Cardiovascular Diabetology 2016 15:42
  24. Several antidiabetic drugs (i.e., sulfonylureas; SU, rosiglitazone) have been reported to be associated with increased risks of cardiovascular diseases (CVD) in patients with type 2 diabetes mellitus (T2DM). D...

    Authors: Huang-Tz Ou, Kai-Cheng Chang, Chung-Yi Li and Jin-Shang Wu
    Citation: Cardiovascular Diabetology 2016 15:41
  25. Soluble tumor necrosis factor receptors 1 and 2 (sTNFR1 and sTNFR2) contribute to experimental diabetic kidney disease, a condition with substantially increased cardiovascular risk when present in patients. Th...

    Authors: Axel C. Carlsson, Carl Johan Östgren, Fredrik H. Nystrom, Toste Länne, Pär Jennersjö, Anders Larsson and Johan Ärnlöv
    Citation: Cardiovascular Diabetology 2016 15:40
  26. Aim of this retrospective study was to compare long-term mortality and incidence of new diseases [diabetes and cardiovascular (CV) disease] in morbidly obese diabetic and nondiabetic patients, undergoing gastr...

    Authors: Antonio E. Pontiroli, Ahmed S. Zakaria, Ermanno Mantegazza, Alberto Morabito, Alessandro Saibene, Enrico Mozzi and Giancarlo Micheletto
    Citation: Cardiovascular Diabetology 2016 15:39
  27. Patients with type 2 diabetes (T2D) have a substantial increased risk for cardiovascular (CV) disease and associated mortality than those without diabetes. Dulaglutide is a once-weekly glucagon-like peptide-1 ...

    Authors: Keith C. Ferdinand, Fady T. Botros, Charles M. Atisso and Philip T. Sager
    Citation: Cardiovascular Diabetology 2016 15:38
  28. A pre-specified meta-analysis of cardiovascular (CV) events from 21 phase 2b/3 dapagliflozin clinical trials was undertaken to characterise the CV profile of dapagliflozin. This showed no increase in CV risk w...

    Authors: Christian Sonesson, Peter A. Johansson, Eva Johnsson and Ingrid Gause-Nilsson
    Citation: Cardiovascular Diabetology 2016 15:37
  29. Patients with angina-like symptoms without myocardial perfusion scintigram (MPS)-verified abnormality may still be at risk for cardiovascular events. We hypothesized that insulin resistance could play a role i...

    Authors: Helena U. Westergren, Sara Svedlund, Remi A. Momo, Juuso I. Blomster, Karin Wåhlander, Erika Rehnström, Peter J. Greasley, Regina Fritsche-Danielson, Jan Oscarsson and Li-Ming Gan
    Citation: Cardiovascular Diabetology 2016 15:36
  30. Diabetes mellitus (DM) is estimated to become the 7th leading cause of death by 2030. Right ventricular dysfunction (RVD) complicating ST elevation myocardial infarction (STEMI) is independently associated wit...

    Authors: Idan Roifman, Nilesh Ghugre, Mohammad I. Zia, Michael E. Farkouh, Anna Zavodni, Graham A. Wright and Kim A. Connelly
    Citation: Cardiovascular Diabetology 2016 15:34
  31. The 1st Cardiovascular Outcome Trial (CVOT) Summit of the Diabetes & Cardiovascular Disease (D&CVD) EASD Study Group was held during the annual meeting on 30 October 2015 in Munich. This summit was organized i...

    Authors: Oliver Schnell, Eberhard Standl, Doina Catrinoiu, Stefano Genovese, Nebojsa Lalic, Jan Skra, Paul Valensi and Antonio Ceriello
    Citation: Cardiovascular Diabetology 2016 15:33
  32. Adenosine has been shown to induce nitric oxide (NO) production via inducible NO synthase (iNOS) activation in vascular smooth muscle cells (VSMCs). Although this is interpreted as a beneficial vasodilating pa...

    Authors: Alberto Nassi, Francesca Malorgio, Serena Tedesco, Andrea Cignarella and Rosa Maria Gaion
    Citation: Cardiovascular Diabetology 2016 15:32
  33. Children with type 1 diabetes (T1D) are at higher risk of early adult-onset cardiovascular disease. We assessed cardiovascular structure and function in adolescents with T1D compared with healthy controls and ...

    Authors: Timothy J. Bradley, Cameron Slorach, Farid H. Mahmud, David B. Dunger, John Deanfield, Livia Deda, Yesmino Elia, Ronnie L. H. Har, Wei Hui, Rahim Moineddin, Heather N. Reich, James W. Scholey, Luc Mertens, Etienne Sochett and David Z. I. Cherney
    Citation: Cardiovascular Diabetology 2016 15:31
  34. Skin collagen Long Wavelength Fluorescence (LWF) is widely used as a surrogate marker for accumulation of advanced glycation end-products. Here we determined the relationship of LWF with glycemia, skin fluores...

    Authors: David R. Sell, Wanjie Sun, Xiaoyu Gao, Christopher Strauch, John M. Lachin, Patricia A. Cleary, Saul Genuth and Vincent M. Monnier
    Citation: Cardiovascular Diabetology 2016 15:30
  35. Epidemiological data on obesity are needed, particularly in patients with type 2 diabetes mellitus (T2DM) and high cardiovascular (CV) risk. We used the baseline data of liraglutide effect and action in diabet...

    Authors: L. Masmiquel, L. A. Leiter, J. Vidal, S. Bain, J. Petrie, E. Franek, I. Raz, A. Comlekci, S. Jacob, L. van Gaal, F. M. M. Baeres, S. P. Marso and M. Eriksson
    Citation: Cardiovascular Diabetology 2016 15:29
  36. There is increasing evidence to suggest that not all individuals with type 2 diabetes mellitus (T2DM) have equal risk for developing cardiovascular disease. We sought to compare the yield of testing for pre-cl...

    Authors: Carlos Henrique Reis Esselin Rassi, Timothy W. Churchill, Carlos A. Fernandes Tavares, Mateus Guimaraes Fahel, Fabricia P. O. Rassi, Augusto H. Uchida, Bernardo L. Wajchenberg, Antonio C. Lerario, Edward Hulten, Khurram Nasir, Márcio S. Bittencourt, Carlos Eduardo Rochitte and Ron Blankstein
    Citation: Cardiovascular Diabetology 2016 15:28
  37. Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with diabetes mellitus (DM). To identify the most effective treatment for CVD, it is paramount to understand the mechani...

    Authors: Sherin Bakhashab, Fahad W. Ahmed, Hans-Juergen Schulten, Ayat Bashir, Sajjad Karim, Abdulrahman L. Al-Malki, Mamdooh A. Gari, Adel M. Abuzenadah, Adeel G. Chaudhary, Mohammed H. Alqahtani, Sahira Lary, Farid Ahmed and Jolanta U. Weaver
    Citation: Cardiovascular Diabetology 2016 15:27
  38. Diabetes is a risk factor for atherosclerosis associated with oxidative stress, inflammation and cell proliferation. The purpose of this study was to evaluate arterial choline uptake and its relationship to at...

    Authors: Sanna Hellberg, Johanna M. U. Silvola, Max Kiugel, Heidi Liljenbäck, Olli Metsälä, Tapio Viljanen, Jari Metso, Matti Jauhiainen, Pekka Saukko, Pirjo Nuutila, Seppo Ylä-Herttuala, Juhani Knuuti, Anne Roivainen and Antti Saraste
    Citation: Cardiovascular Diabetology 2016 15:26
  39. ANGPTL8 also called betatrophin is a regulator of lipid metabolism through its interaction with ANGPTL3. It has also been suggested to play a role in insulin resistance and beta-cell proliferation. Based on it...

    Authors: Mohamed Abu-Farha, Jehad Abubaker, Irina Al-Khairi, Preethi Cherian, Fiona Noronha, Sina Kavalakatt, Abdelkrim Khadir, Kazem Behbehani, Monira Alarouj, Abdullah Bennakhi and Naser Elkum
    Citation: Cardiovascular Diabetology 2016 15:25
  40. A novel MRI technique, employing dual contrast manganese-enhanced MRI (MEMRI) and delayed enhancement MRI (DEMRI), can evaluate the physiologically unstable peri-infarct region. Dual contrast MEMRI–DEMRI enab...

    Authors: Ildiko Toma, Paul J. Kim, Rajesh Dash, Michael V. McConnell, Dwight Nishimura, Phillip Harnish and Phillip C. Yang
    Citation: Cardiovascular Diabetology 2016 15:24
  41. Gestational diabetes mellitus (GDM) is a significant risk factor for cardiovascular disease (CVD) in later life. Pentraxin 3 (PTX3) is an essential component of innate immunity and independently associated wit...

    Authors: Tove Lekva, Annika Elisabeth Michelsen, Jens Bollerslev, Errol R. Norwitz, Pål Aukrust, Tore Henriksen and Thor Ueland
    Citation: Cardiovascular Diabetology 2016 15:23
  42. Patients with type 2 diabetes mellitus (T2DM) are at high risk for cardiovascular events. The aim of the study was to assess whether global longitudinal strain (GLS) provides prognostic value in these patients.

    Authors: Ju-Hua Liu, Yan Chen, Michele Yuen, Zhe Zhen, Carmen Wing-Sze Chan, Karen Siu-Ling Lam, Hung-Fat Tse and Kai-Hang Yiu
    Citation: Cardiovascular Diabetology 2016 15:22
  43. Glucagon-like peptide-1 (GLP-1) is an incretin hormone, which gets secreted in response to nutritional stimuli from the gut mediating glucose-dependent insulin secretion. Interestingly, GLP-1 was recently foun...

    Authors: Corinna Lebherz, Florian Kahles, Katja Piotrowski, Michael Vogeser, Ann Christina Foldenauer, Kirsten Nassau, Erich Kilger, Nikolaus Marx, Klaus G. Parhofer and Michael Lehrke
    Citation: Cardiovascular Diabetology 2016 15:21
  44. The genetic contribution to complex diseases or traits, including cardio-metabolic traits, has been elucidated recently by large-scale genome-wide association studies. These genome-wide association studies hav...

    Authors: Yun Kyoung Kim, Mi Yeong Hwang, Young Jin Kim, Sanghoon Moon, Sohee Han and Bong-Jo Kim
    Citation: Cardiovascular Diabetology 2016 15:20
  45. Abnormalities in lipid and glucose metabolism are constantly observed in type 2 diabetes. However, these abnormalities can be ameliorated by polydatin. Considering the important role of proprotein convertase s...

    Authors: Yu Wang, Jiantao Ye, Jie Li, Cheng Chen, Junying Huang, Peiqing Liu and Heqing Huang
    Citation: Cardiovascular Diabetology 2016 15:19
  46. We tested the hypothesis that glucose-induced hyperosmolarity, occurring in diabetic hyperglycemia, promotes retinal angiogenesis, and that interference with osmolarity signaling ameliorates excessive angiogen...

    Authors: Rosalinda Madonna, Gaia Giovannelli, Pamela Confalone, Francesca Vera Renna, Yong-Jian Geng and Raffaele De Caterina
    Citation: Cardiovascular Diabetology 2016 15:18
  47. Despite its beneficial role on insulin resistance and atherosclerosis, adiponectin has been repeatedly reported as an independent positive predictor of cardiovascular mortality.

    Authors: Lorena Ortega Moreno, Massimiliano Copetti, Andrea Fontana, Concetta De Bonis, Lucia Salvemini, Vincenzo Trischitta and Claudia Menzaghi
    Citation: Cardiovascular Diabetology 2016 15:17
  48. The effect of gestational diabetes mellitus (GDM) on cardiovascular diseases (CVD) is not assessed within the first 10 years postpartum, regardless of subsequent diabetes. The aim of this study was to determin...

    Authors: Karine Goueslard, Jonathan Cottenet, Anne-Sophie Mariet, Maurice Giroud, Yves Cottin, Jean-Michel Petit and Catherine Quantin
    Citation: Cardiovascular Diabetology 2016 15:15

Cardiovascular Diabetology is affiliated with Sackler Faculty of Medicine, Tel-Aviv University

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