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  1. Studies that have reported lower risk for cardiovascular outcomes in users of Sodium–Glucose Cotransporter-2 Inhibitors (SGLT-2i) are limited by residual cofounding and lack of information on prior cardiovascu...

    Authors: Dorte Vistisen, Bendix Carstensen, Patorno Elisabetta, Stefanie Lanzinger, Elise Chia-Hui Tan, Daisuke Yabe, Dae Jung Kim, Wayne H.-H. Sheu, Cheli Melzer-Cohen, Reinhard W. Holl, Júlio Núñez, Kyoung Hwa Ha, Sigrun Halvorsen, Gisle Langslet, Avraham Karasik, Thomas Nyström…
    Citation: Cardiovascular Diabetology 2023 22:233
    Content type: Research Published on:

  2. Insulin resistance (IR) can be effectively assessed using the dependable surrogate biomarker triglyceride-glucose (TyG) index. In various critical care contexts, like contrast-induced acute kidney injury (AKI)...

    Authors: Zewen Yang, Hongxia Gong, Fuqiang Kan and Ningning Ji
    Citation: Cardiovascular Diabetology 2023 22:232
    Content type: Research Published on:

  3. The triglyceride-glucose (TyG) index has been evaluated as a reliable surrogate for insulin resistance (IR) and has been proven to be a predictor of poor outcomes in patients with cardiovascular diseases. Howe...

    Authors: Zhenguo Wu, Lin Xie, Dachuan Guo, Sha Chen, Xiaoyu Liu, Xiangfei Sun, Juan Wang, Yerui Zhang, Li Liu, Huiliang Cui, Dejin Zang and Jianmin Yang
    Citation: Cardiovascular Diabetology 2023 22:230
    Content type: Research Published on:

  5. Today, diabetes mellitus (DM) has become a worldwide concern. DM is a major risk factor for the development of cardiovascular diseases (CVD). Eligible patients with CVD are treated invasively by percutaneous c...

    Authors: Hong Wang, Quannan Zu, Hairong Tang, Ming Lu, Rongfa Chen and Zhiren Yang
    Citation: Cardiovascular Diabetology 2023 22:228
    Content type: Review Published on:

  6. Outcomes of diabetes screening in contemporary, multi-ethnic populations are unknown. We examined the association of prior outpatient diabetes screening with the risks of cardiovascular events and mortality in...

    Authors: Calvin Ke, Anna Chu, Baiju R. Shah, Sheldon Tobe, Karen Tu, Jiming Fang, Haris Vaid, Peter Liu, Aishah Cader and Douglas S. Lee
    Citation: Cardiovascular Diabetology 2023 22:227
    Content type: Research Published on:

  7. The global prevalence of metabolic syndrome and its association with increased morbidity and mortality has been rigorously studied. However, the true prevalence of “metabolic health”, i.e. individuals without ...

    Authors: Hadas Ben-Assayag, Rafael Y. Brzezinski, Shlomo Berliner, David Zeltser, Itzhak Shapira, Ori Rogowski, Sharon Toker, Roy Eldor and Shani Shenhar-Tsarfaty
    Citation: Cardiovascular Diabetology 2023 22:226
    Content type: Research Published on:

  8. Estimated glucose disposal rate (eGDR), a simple and noninvasive measure of insulin resistance, has been proven to be an independent risk factor for first-time stroke and all-cause mortality. In this study, we...

    Authors: Zhengzhao Lu, Yunyun Xiong, Xueyan Feng, Kaixuan Yang, Hongqiu Gu, Xingquan Zhao, Xia Meng and Yongjun Wang
    Citation: Cardiovascular Diabetology 2023 22:225
    Content type: Research Published on:

  9. Diabetes and hyperlipidaemia are both risk factors for coronary artery disease, and both are associated with a high triglyceride-glucose index (TyG index). The TyG index has been presented as a marker of insul...

    Authors: Jiao Li, Zixian Dong, Hao Wu, Yue Liu, Yafang Chen, Si Li, Yufan Zhang, Xin Qi and Liping Wei
    Citation: Cardiovascular Diabetology 2023 22:224
    Content type: Research Published on:

  10. High-sensitivity C-reaction protein (hsCRP), a biomarker of residual inflammatory risk, has been demonstrated with poor cardiovascular outcomes. We aimed to investigate the prognostic value of hsCRP in patient...

    Authors: Le Li, Shangyu Liu, Zhuxin Zhang, Likun Zhou, Zhenhao Zhang, Yulong Xiong, Zhao Hu and Yan Yao
    Citation: Cardiovascular Diabetology 2023 22:223
    Content type: Research Published on:

  11. Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality, being twofold to fourfold more common in patients with type 2 diabetes mellitus (T2DM) than in individuals withou...

    Authors: Massimiliano Ruscica, Chiara Macchi, Angelica Giuliani, Alessandra Stefania Rizzuto, Deborah Ramini, Matilde Sbriscia, Stefano Carugo, Anna Rita Bonfigli, Alberto Corsini, Fabiola Olivieri and Jacopo Sabbatinelli
    Citation: Cardiovascular Diabetology 2023 22:222
    Content type: Research Published on:

  12. Early postoperative glycemic variability is associated with worse outcome after cardiac surgery, but the underlying mechanisms remain unknown. This study aimed to describe the relationship between postoperativ...

    Authors: Etienne Chazal, Lucas Morin, Sidney Chocron, Philippe Lassalle, Sebastien Pili-Floury, Lucie Salomon du Mont, David Ferreira, Emmanuel Samain, Andrea Perrotti and Guillaume Besch
    Citation: Cardiovascular Diabetology 2023 22:221
    Content type: Research Published on:

  13. Semaglutide is a glucose-lowering treatment for type 2 diabetes (T2D) with demonstrated cardiovascular benefits; semaglutide may also have kidney-protective effects. This post hoc analysis investigated the associ...

    Authors: Peter Rossing, Stephen C. Bain, Heidrun Bosch-Traberg, Ekaterina Sokareva, Hiddo J. L. Heerspink, Søren Rasmussen and Linda G. Mellbin
    Citation: Cardiovascular Diabetology 2023 22:220
    Content type: Research Published on:

  14. Clinical observations suggest a complex relationship between obesity and coronary artery disease (CAD). This study aimed to characterize the intermediate metabolism phenotypes among obese patients with CAD and...

    Authors: Chong-Yu Zhang, Ru-Qin Xu, Xiao-Qiao Wang, Lin-Feng Sun, Pei Mo, Ren-Jie Cai, Xiao-Zhen Lin, Cheng-Feng Luo, Wen-Chao Ou, Lie-Jing Lu, Yun Zhong and Jia-Yuan Chen
    Citation: Cardiovascular Diabetology 2023 22:219
    Content type: Research Published on:

  15. As cardiovascular disease (CVD) is a leading cause of death for patients with diabetes mellitus (DM), we aimed to find important factors that predict cardiovascular (CV) risk using a machine learning (ML) appr...

    Authors: Hanna Kwiendacz, Agata M. Wijata, Jakub Nalepa, Julia Piaśnik, Justyna Kulpa, Mikołaj Herba, Sylwia Boczek, Kamil Kegler, Mirela Hendel, Krzysztof Irlik, Janusz Gumprecht, Gregory Y. H. Lip and Katarzyna Nabrdalik
    Citation: Cardiovascular Diabetology 2023 22:218
    Content type: Research Published on:

  16. Agonism at the receptor for the glucose-dependent insulinotropic polypeptide (GIPR) is a key component of the novel unimolecular GIPR:GLP-1R co-agonists, which are among the most promising drugs in clinical de...

    Authors: Stephan Sachs, Anna Götz, Brian Finan, Annette Feuchtinger, Richard D. DiMarchi, Yvonne Döring, Christian Weber, Matthias H. Tschöp, Timo D. Müller and Susanna M. Hofmann
    Citation: Cardiovascular Diabetology 2023 22:217
    Content type: Research Published on:

  17. Myocardial microvascular injury is the key event in early diabetic heart disease. The injury of myocardial microvascular endothelial cells (CMECs) is the main cause and trigger of myocardial microvascular dise...

    Authors: Xide Shi, Chao Liu, Jiangwei Chen, Shiqiang Zhou, Yajuan Li, Xingcheng Zhao, Jinliang Xing, Junhui Xue, Fengzhou Liu and Fei Li
    Citation: Cardiovascular Diabetology 2023 22:216
    Content type: Research Published on:

  18. In AFFIRM-AHF, treatment of iron deficiency with intravenous ferric carboxymaltose (FCM) reduced the risk of heart failure (HF) hospitalization and improved quality of life (QoL) vs placebo in patients stabili...

    Authors: Giuseppe Rosano, Piotr Ponikowski, Cristiana Vitale, Stefan D. Anker, Javed Butler, Vincent Fabien, Gerasimos Filippatos, Bridget-Anne Kirwan, Iain C. Macdougall, Marco Metra, Frank Ruschitzka, Vasuki Kumpeson, Udo-Michael Goehring, Peter van der Meer and Ewa A. Jankowska
    Citation: Cardiovascular Diabetology 2023 22:215
    Content type: Research Published on:

  19. Cardiac steatosis is an early yet overlooked feature of diabetic cardiomyopathy. There is no available therapy to treat this condition. Tyrosine kinase inhibitors (TKIs) are used as first or second-line therap...

    Authors: Yue Gu, Elisa Avolio, Valeria V Alvino, Anita C Thomas, Andrew Herman, Poppy J Miller, Niall Sullivan, Ashton Faulkner and Paolo Madeddu
    Citation: Cardiovascular Diabetology 2023 22:214
    Content type: Research Published on:

  20. The accumulation of advanced glycation end products (AGEs) is associated with cardiovascular events in patients with cardiovascular disease (CVD). However, the relationship between the AGEs measured by an AGEs...

    Authors: Tomoya Hirai, Kazuhiro Fujiyoshi, Satoru Yamada, Takuya Matsumoto, Junko Kikuchi, Kohki Ishida, Miwa Ishida, Kyo Shigeta and Taiki Tojo
    Citation: Cardiovascular Diabetology 2023 22:213
    Content type: Research Published on:

  21. While a low-carbohydrate diet (LCD) reduces HbA1c in patients with type 2 diabetes (T2D), the associated high intake of fat may adversely affect cardiovascular risk factors. To address this, we examined the ef...

    Authors: Eva M. Gram-Kampmann, Thomas B. Olesen, Camilla D. Hansen, Mie B. Hugger, Jane M. Jensen, Aase Handberg, Henning Beck-Nielsen, Aleksander Krag, Michael H. Olsen and Kurt Højlund
    Citation: Cardiovascular Diabetology 2023 22:212
    Content type: Research Published on:

  22. Heterogeneous metabolic clusters have been identified in diabetic and prediabetic states. It is not known whether such pathophysiologic clusters impact survival in at-risk persons being evaluated for coronary ...

    Authors: Katsiaryna Prystupa, Graciela E. Delgado, Angela P. Moissl, Marcus E. Kleber, Andreas L. Birkenfeld, Martin Heni, Andreas Fritsche, Winfried März and Robert Wagner
    Citation: Cardiovascular Diabetology 2023 22:211
    Content type: Research Published on:

  23. Atherogenic index of plasma (AIP) has been confirmed as a novel marker for myocardial infarction (MI), but few evidence on the long-term AIP and MI risk in general populations. We thus aimed to evaluate the re...

    Authors: Yijun Zhang, Shuohua Chen, Xue Tian, Penglian Wang, Qin Xu, Xue Xia, Xiaoli Zhang, Jing Li, Fen Liu, Shouling Wu and Anxin Wang
    Citation: Cardiovascular Diabetology 2023 22:210
    Content type: Research Published on:

  24. The concept of early vascular aging (EVA) represents a potentially beneficial model for future research into the pathophysiological mechanisms underlying the early manifestations of cardiovascular disease. For...

    Authors: Alicia Saz-Lara, Iván Cavero-Redondo, Carlos Pascual-Morena, Irene Martínez-García, Eva Rodríguez-Gutiérrez, Maribel Lucerón-Lucas-Torres, Bruno Bizzozero-Peroni, Nerea Moreno-Herráiz and Arturo Martínez-Rodrigo
    Citation: Cardiovascular Diabetology 2023 22:209
    Content type: Research Published on:

  25. Empagliflozin reduces the risk of cardiovascular disease (CVD) in patients with type 2 diabetes (T2DM) and high cardiovascular risk via mechanisms which have not been fully explained. The mechanisms of such be...

    Authors: Elena Fortin, Magnus Lundin, Linda Mellbin, Anna Norhammar, Per Näsman, Stina Smetana, Peder Sörensson, Ele Ferrannini, Lars Rydén and Giulia Ferrannini
    Citation: Cardiovascular Diabetology 2023 22:208
    Content type: Research Published on:

  26. Emerging evidence suggests that remnant cholesterol (RC) is strongly associated with an increased incidence of cardiometabolic diseases (CMD). However, the causality have not been confirmed. We aimed to evalua...

    Authors: Baoyi Guan, Anlu Wang and Hao Xu
    Citation: Cardiovascular Diabetology 2023 22:207
    Content type: Research Published on:

  27. The differences in fat deposition sites exhibit varying degrees of systemic inflammatory responses and organ damage, especially in obese individuals with excessive visceral fat. Visceral fat, which is closely ...

    Authors: Jinquan Bai, Chao Gao, Xiaolu Li, Hong Pan, Shuting Wang, Zhenzhou Shi and Tong Zhang
    Citation: Cardiovascular Diabetology 2023 22:206
    Content type: Research Published on:

  28. The atherogenic index of plasma (AIP) can reflect the burden of atherosclerosis. Hyperglycemia is one of the leading causes of atherosclerosis. However, the relationship between AIP and prediabetes is rarely s...

    Authors: Xiaodan Zheng, Xin Zhang, Yong Han, Haofei Hu and Changchun Cao
    Citation: Cardiovascular Diabetology 2023 22:205
    Content type: Research Published on:

  29. We assessed whether hepatic steatosis with or without significant fibrosis (determined by validated non-invasive biomarkers) is associated with an increased 10-year estimated risk for cardiovascular disease (C...

    Authors: Alessandro Mantovani, Mario Luca Morieri, Luisa Palmisano, Maria Masulli, Efisio Cossu, Marco Giorgio Baroni, Katia Bonomo, Flavia Agata Cimini, Gisella Cavallo, Raffaella Buzzetti, Carmen Mignogna, Frida Leonetti, Simonetta Bacci, Roberto Trevisan, Riccardo Maria Pollis, Raffaella Aldigeri…
    Citation: Cardiovascular Diabetology 2023 22:204
    Content type: Research Published on:

  30. Albuminuria has been suggested as an atherosclerotic risk factor among the general population. However, whether this association will be amplified in patients with coronary artery disease (CAD) is unknown. It ...

    Authors: Xueqin Lin, Wei Song, Yang Zhou, Yuwei Gao, Yani Wang, Yun Wang, Yuchen Liu, Lin Deng, Yin Liao, Bo Wu, Shiqun Chen, Liling Chen and Yong Fang
    Citation: Cardiovascular Diabetology 2023 22:203
    Content type: Research Published on:

  31. This study aimed to investigate the effect of glycemic variability (GV), determined using a continuous glucose monitoring system (CGMS), on left ventricular reverse remodeling (LVRR) after ST-segment elevation...

    Authors: Yohei Hanajima, Noriaki Iwahashi, Jin Kirigaya, Mutsuo Horii, Yugo Minamimoto, Masaomi Gohbara, Takeru Abe, Kozo Okada, Yasushi Matsuzawa, Masami Kosuge, Toshiaki Ebina and Kiyoshi Hibi
    Citation: Cardiovascular Diabetology 2023 22:202
    Content type: Research Published on:

  32. Insulin is commonly used in type 2 diabetes mellitus (T2DM) to achieve glycemic control. However, recent evidence showed that insulin use is associated with poor outcomes in the context of heart failure (HF). ...

    Authors: Ke Shi, Ge Zhang, Hang Fu, Shan Huang, Hua-Yan Xu, Yue Gao, Rui Shi, Wei-Feng Yan, Wen-Lei Qian, Yuan Li, Ying-Kun Guo and Zhi-Gang Yang
    Citation: Cardiovascular Diabetology 2023 22:201
    Content type: Research Published on:

  33. Various predictive models have been developed for predicting the incidence of coronary heart disease (CHD), but none of them has had optimal predictive value. Although these models consider diabetes as an impo...

    Authors: Seyed Reza Mirjalili, Sepideh Soltani, Zahra Heidari Meybodi, Pedro Marques-Vidal, Alexander Kraemer and Mohammadtaghi Sarebanhassanabadi
    Citation: Cardiovascular Diabetology 2023 22:200
    Content type: Research Published on:

  34. We aimed to identify a lipidic profile associated with type 2 diabetes mellitus (T2DM) development in coronary heart disease (CHD) patients, to provide a new, highly sensitive model which could be used in clin...

    Authors: Alejandro Villasanta-Gonzalez, Marina Mora-Ortiz, Juan F. Alcala-Diaz, Lorenzo Rivas-Garcia, Jose D. Torres-Peña, Asuncion Lopez-Bascon, Monica Calderon-Santiago, Antonio P. Arenas-Larriva, Feliciano Priego‑Capote, Maria M. Malagon, Fabian Eichelmann, Pablo Perez-Martinez, Javier Delgado-Lista, Matthias B. Schulze, Antonio Camargo and Jose Lopez-Miranda
    Citation: Cardiovascular Diabetology 2023 22:199
    Content type: Research Published on:

  35. Early identification of populations at high cardiovascular disease (CVD) risk and improvement of risk factors can significantly decrease the probability of CVD development and improve outcomes. Insulin resista...

    Authors: Xiao-ling Cai, Yi-fei Xiang, Xiao-fang Chen, Xue-qin Lin, Bi-ting Lin, Geng-yu Zhou, Lin Yu, Yan-song Guo and Kai-yang Lin
    Citation: Cardiovascular Diabetology 2023 22:198
    Content type: Research Published on:

  36. Patients with heart failure have increased cardiac filling pressures, circulating natriuretic peptides, and physical signs of fluid retention, which are related to sodium retention by the kidneys and are allev...

    Authors: Milton Packer
    Citation: Cardiovascular Diabetology 2023 22:197
    Content type: Comment Published on:

  38. Type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease (CKD), are recognized among the most disruptive public health issues of the current century. A large body of evidence from epidemi...

    Authors: Marella Marassi and Gian Paolo Fadini
    Citation: Cardiovascular Diabetology 2023 22:195
    Content type: Review Published on:

  39. The overactivation of mineralocorticoid receptor (MR) plays a key pathological role in the progression of cardiovascular and renal diseases by promoting pro-inflammatory and pro-fibrotic signaling. Recently, i...

    Authors: Atsushi Tanaka, Hirotaka Shibata, Takumi Imai, Hisako Yoshida, Motoaki Miyazono, Naohiko Takahashi, Daiju Fukuda, Yosuke Okada, Hiroki Teragawa, Satoru Suwa, Keisuke Kida, Masao Moroi, Isao Taguchi, Shigeru Toyoda, Michio Shimabukuro, Kengo Tanabe…
    Citation: Cardiovascular Diabetology 2023 22:194
    Content type: Study Protocol Published on:

  40. We aimed to examine the association between smoking behavior change and risk of cardiovascular disease (CVD) incidence and mortality in patients with type 2 diabetes mellitus (T2DM).

    Authors: Su-Min Jeong, Jung Eun Yoo, Junhee Park, Wonyoung Jung, Kyu Na Lee, Kyungdo Han, Cheol Min Lee, Ki-Woong Nam, Seung-Pyo Lee and Dong Wook Shin
    Citation: Cardiovascular Diabetology 2023 22:193
    Content type: Research Published on:

  41. The prevalence of obesity and atrial fibrillation (AF), which are inextricably linked, is rapidly increasing worldwide. Obesity rates are higher among patients with AF than healthy individuals. Some epidemiolo...

    Authors: Hongyang Shu, Jia Cheng, Na Li, Zixuan Zhang, Jiali Nie, Yizhong Peng, Yan Wang, Dao Wen Wang and Ning Zhou
    Citation: Cardiovascular Diabetology 2023 22:192
    Content type: Review Published on:

  42. Given the cumulative evidence on the effectiveness of sodium-glucose cotransporter 2 inhibitors (SGLT2is) on chronic heart failure, demand is emerging for further information on their effects in patients who a...

    Authors: Sohee Park, Han Eol Jeong, Hyesung Lee, Seng Chan You and Ju-Young Shin
    Citation: Cardiovascular Diabetology 2023 22:191
    Content type: Research Published on:

  43. Triglyceride-glucose (TyG) index is an efficient indicator of insulin resistance and is proven to be a valuable marker in several cardiovascular diseases. However, the relationship between TyG index and cardia...

    Authors: Yang Boshen, Zhu Yuankang, Zheng Xinjie, Li Taixi, Niu kaifan, Wang Zhixiang, Song Juan, Duan Junli, Li Suiji, Lu Xia and Shen Chengxing
    Citation: Cardiovascular Diabetology 2023 22:190
    Content type: Research Published on:

  44. The relationship between stress hyperglycemia and long-term prognosis in acute decompensated heart failure (ADHF) patients is unknown. This study investigated the associations of stress hyperglycemia with mort...

    Authors: Qing Zhou, Jie Yang, Wenyao Wang, Chunli Shao, Xinwei Hua and Yi-Da Tang
    Citation: Cardiovascular Diabetology 2023 22:189
    Content type: Research Published on:

  45. Sodium-glucose co-transporter-2 inhibitors displayed cardiovascular benefits in type 2 diabetes mellitus in previous studies; however, there were some heterogeneities regarding respective cardiovascular outcom...

    Authors: Jaehyun Lim, You-Jung Choi, Bong Sung Kim, Tae-Min Rhee, Hyun-Jung Lee, Kyung-Do Han, Jun-Bean Park, Jin Oh Na, Yong-Jin Kim, Heesun Lee and Hyung-Kwan Kim
    Citation: Cardiovascular Diabetology 2023 22:188
    Content type: Research Published on:

  46. Elevated triglyceride levels are a clinically useful marker of remnant cholesterol. It is unknown whether triglycerides are associated with residual cardiovascular risk in CVD-naïve patients with newly diagnos...

    Authors: Frederik Pagh Bredahl Kristensen, Diana Hedevang Christensen, Martin Bødtker Mortensen, Michael Maeng, Johnny Kahlert, Henrik Toft Sørensen and Reimar Wernich Thomsen
    Citation: Cardiovascular Diabetology 2023 22:187
    Content type: Research Published on:

  47. Coronary computed tomography angiography (CCTA)-derived fractional flow reserve (CT-FFR) enables physiological assessment and risk stratification, which is of significance in diabetic patients with nonobstruct...

    Authors: Zinuan Liu, Yipu Ding, Guanhua Dou, Xi Wang, Dongkai Shan, Bai He, Jing Jing, Tao Li, Yundai Chen and Junjie Yang
    Citation: Cardiovascular Diabetology 2023 22:186
    Content type: Research Published on:

  48. Although sodium-glucose cotransporter 2 inhibitors (SGLT2i) have demonstrated cardiovascular benefits in patients with type 2 diabetes mellitus, real-world evidence regarding their benefits to diabetic patient...

    Authors: Young Sang Lyu, Seok Oh, Jin Hwa Kim, Sang Yong Kim and Myung Ho Jeong
    Citation: Cardiovascular Diabetology 2023 22:185
    Content type: Research Published on:

    The Correction to this article has been published in Cardiovascular Diabetology 2023 22:242

  49. The relationship between sodium glucose co-transporter 2 inhibitors (SGLT2i) and trimethylamine N-oxide (TMAO) following acute myocardial infarction (AMI) is not yet explored.

    Authors: Faisal Aziz, Norbert J. Tripolt, Peter N. Pferschy, Ewald Kolesnik, Harald Mangge, Pero Curcic, Markus Hermann, Andreas Meinitzer, Dirk von Lewinski and Harald Sourij
    Citation: Cardiovascular Diabetology 2023 22:184
    Content type: Research Published on:

  50. To investigate the association of variability in metabolic parameters such as total cholesterol concentrations (TC), uric acid (UA), body mass index (BMI), visceral adiposity index (VAI) and systolic blood pre...

    Authors: Ning Chen, Yu-Hong Liu, Li-Kun Hu, Lin-Lin Ma, Yu Zhang, Xi Chu, Jing Dong and Yu-Xiang Yan
    Citation: Cardiovascular Diabetology 2023 22:183
    Content type: Research Published on:
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