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  1. Endothelial dysfunction is an early marker of cardiovascular disease so endothelial and arterial stiffness indexes are good indicators of vascular health. We aimed to assess whether the presence of diabetic fo...

    Authors: Antonino Tuttolomondo, Alessandra Casuccio, Giovanni Guercio, Carlo Maida, Alessandro Del Cuore, Domenico Di Raimondo, Irene Simonetta, Danilo Di Bona, Rosaria Pecoraro, Vittoriano Della Corte, Eliana Gulotta, Gaspare Gulotta and Antonio Pinto
    Citation: Cardiovascular Diabetology 2017 16:2
  2. Diastolic dysfunction is a major cause of morbidity in obese individuals. We aimed to assess the ability of magnetic resonance imaging (MRI) derived left atrial (LA) strain to detect early diastolic dysfunctio...

    Authors: Morgane Evin, Kathryn M. Broadhouse, Fraser M. Callaghan, Rachel T. McGrath, Sarah Glastras, Rebecca Kozor, Samantha L. Hocking, Jérôme Lamy, Alban Redheuil, Nadjia Kachenoura, Greg R. Fulcher, Gemma A. Figtree and Stuart M. Grieve
    Citation: Cardiovascular Diabetology 2016 15:164
  3. Individuals with peripheral artery disease (PAD) often have reduced physical activity, which may increase the future risk of diabetes mellitus. Although diabetes is a risk factor for PAD, whether low ankle-bra...

    Authors: Simin Hua, Laura R. Loehr, Hirofumi Tanaka, Gerardo Heiss, Josef Coresh, Elizabeth Selvin and Kunihiro Matsushita
    Citation: Cardiovascular Diabetology 2016 15:163
  4. Liraglutide, a GLP-1 analogue, exerts several beneficial non-glycemic effects in patients with type-2 diabetes (T2DM), such as those on body weight, blood pressure, plasma lipids and inflammation markers. Howe...

    Authors: Manfredi Rizzo, Ali A. Rizvi, Angelo Maria Patti, Dragana Nikolic, Rosaria Vincenza Giglio, Giuseppa Castellino, Giovanni Li Volti, Massimiliano Caprio, Giuseppe Montalto, Vincenzo Provenzano, Stefano Genovese and Antonio Ceriello
    Citation: Cardiovascular Diabetology 2016 15:162
  5. Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) is a major contributor to the development of atherosclerotic process. In a previous work, we demonstrated that the insulin receptor ...

    Authors: N. Beneit, C. E. Fernández-García, J. L. Martín-Ventura, L. Perdomo, Ó. Escribano, J. B. Michel, G. García-Gómez, S. Fernández, S. Díaz-Castroverde, J. Egido, A. Gómez-Hernández and M. Benito
    Citation: Cardiovascular Diabetology 2016 15:161
  6. There are limited data regarding the effect of diabetes mellitus (DM) on the risks of both appropriate and inappropriate implantable cardioverter defibrillator (ICD) therapy. The present study was designed to ...

    Authors: Hillel Steiner, Michael Geist, Ilan Goldenberg, Mahmoud Suleiman, Michael Glikson, Alexander Tenenbaum, Moshe Swissa, Enrique Z. Fisman, Gregory Golovchiner, Boris Strasberg and Alon Barsheshet
    Citation: Cardiovascular Diabetology 2016 15:160
  7. Visceral fat plays a central role in the development of metabolic syndrome and atherosclerotic cardiovascular diseases. The association of visceral fat accumulation with cardio-metabolic diseases has been repo...

    Authors: Yoshinari Obata, Norikazu Maeda, Yuya Yamada, Koji Yamamoto, Seiji Nakamura, Masaya Yamaoka, Yoshimitsu Tanaka, Shigeki Masuda, Hirofumi Nagao, Shiro Fukuda, Yuya Fujishima, Shunbun Kita, Hitoshi Nishizawa, Tohru Funahashi, Ken-ichi Matsubara, Yuji Matsuzawa…
    Citation: Cardiovascular Diabetology 2016 15:159
  8. Smoking is associated with increased macrovascular and microvascular complications in people with diabetes. In addition to other concomitant vascular perturbations, it also seems to influence the cardiometabol...

    Authors: Debasish Kar, Clare Gillies, Francesco Zaccardi, David Webb, Samuel Seidu, Solomon Tesfaye, Melanie Davies and Kamlesh Khunti
    Citation: Cardiovascular Diabetology 2016 15:158
  9. The potential benefit of SGLT2 inhibitors in metabolic syndrome is with prediabetic stage unclear. This work was undertaken to investigate the non-glycemic effect of empagliflozin on metabolic syndrome rats wi...

    Authors: Hiroaki Kusaka, Nobutaka Koibuchi, Yu Hasegawa, Hisao Ogawa and Shokei Kim-Mitsuyama
    Citation: Cardiovascular Diabetology 2016 15:157
  10. Hyperinsulinemia and insulin resistance have been recently recognized as an important cause of atherosclerosis. Clinical studies have also found that expression of the estrogen receptor is closely related to t...

    Authors: Jia Min, Zhong Weitian, Cai Peng, Peng Yan, Zhang Bo, Wang Yan, Bai Yun and Wang Xukai
    Citation: Cardiovascular Diabetology 2016 15:156
  11. The leading cause of death among the obese population is heart failure and stroke prompted by structural and functional changes in the heart. The molecular mechanisms that underlie obesity-related cardiac remo...

    Authors: Elisa Lucas, Rocio Vila-Bedmar, Alba C. Arcones, Marta Cruces-Sande, Victoria Cachofeiro, Federico Mayor Jr. and Cristina Murga
    Citation: Cardiovascular Diabetology 2016 15:155
  12. Results of longitudinal researches regarding the temporal relationship between dyslipidemia and insulin resistance (IR) are inconsistent. This study assessed temporal relationships of blood lipids with IR and ...

    Authors: Tianshu Han, Yu Cheng, Shuang Tian, Li Wang, Xi Liang, Wei Duan, Lixin Na and Changhao Sun
    Citation: Cardiovascular Diabetology 2016 15:154
  13. Trelagliptin, an oral DPP-4 inhibitor, which is administered once per week and characterized by a long half-life in blood. The effects of trelagliptin on vascular endothelial functions have not been clarified ...

    Authors: Satoshi Ida, Kazuya Murata, Katunori Betou, Chiaki Kobayashi, Yuki Ishihara, Kanako Imataka, Akihiro Uchida, Kou Monguchi, Ryutaro Kaneko, Ryoko Fujiwara and Hiroka Takahashi
    Citation: Cardiovascular Diabetology 2016 15:153
  14. Vascular disease in diabetes is initiated by monocyte adhesion to vascular endothelium, transmigration and formation of foam cells. Increasing clinical evidence supports a role for the secretory protein, cyclo...

    Authors: Surya Ramachandran, Anandan Vinitha and Cheranellore Chandrasekharan Kartha
    Citation: Cardiovascular Diabetology 2016 15:152
  15. Patients with diabetes mellitus (DM) have an increased risk of developing heart failure (HF). Further, DM is associated with poor prognosis in patients with HF. Our aim was to determine whether DM has any impa...

    Authors: Nuria Alonso, Josep Lupón, Jaume Barallat, Marta de Antonio, Mar Domingo, Elisabet Zamora, Pedro Moliner, Amparo Galán, Javier Santesmases, Cruz Pastor, Dídac Mauricio and Antoni Bayes-Genis
    Citation: Cardiovascular Diabetology 2016 15:151
  16. No conclusive evidence has been obtained yet on the significance of the effects of dipeptidyl peptidase-4 (DPP-4 inhibitor) treatment on the arterial stiffness in clinical settings. In addition, the effects of...

    Authors: Hirofumi Tomiyama, Takashi Miwa, Kenshi Kan, Munehide Matsuhisa, Haruo Kamiya, Mamoru Nanasato, Tomoki Kitano, Hiroaki Sano, Jun Ohno, Masato Iida, Masataka Sata, Hirotsugu Yamada, Koji Maemura, Atsushi Tanaka, Toyoaki Murohara and Koichi Node
    Citation: Cardiovascular Diabetology 2016 15:150
  17. Data regarding long-term association of metabolic syndrome (MetS) with adverse outcomes are conflicting. We aim to determine the independent association of MetS (based on its different definitions) with 20 yea...

    Authors: Arwa Younis, Anan Younis, Boaz Tzur, Yael Peled, Nir Shlomo, Ilan Goldenberg, Enrique Z. Fisman, Alexander Tenenbaum and Robert Klempfner
    Citation: Cardiovascular Diabetology 2016 15:149
  18. The cardio-ankle vascular index (CAVI) and brachial-ankle pulse wave velocity (baPWV) can reflect both central and peripheral arterial stiffness. Metabolic syndrome (MetS) and its components may increase arter...

    Authors: Leticia Gomez-Sanchez, Luis Garcia-Ortiz, M. Carmen Patino-Alonso, Jose I. Recio-Rodriguez, Rigo Fernando, Ruth Marti, Cristina Agudo-Conde, Emiliano Rodriguez-Sanchez, Jose A. Maderuelo-Fernandez, Rafel Ramos and Manuel A. Gomez-Marcos
    Citation: Cardiovascular Diabetology 2016 15:148
  19. Although numerous studies and metanalysis have shown the beneficial effect of statin therapy in CVD secondary prevention, there is still controversy such the use of statins for primary CVD prevention in patien...

    Authors: Ferdinando Carlo Sasso, Nadia Lascar, Antonella Ascione, Ornella Carbonara, Luca De Nicola, Roberto Minutolo, Teresa Salvatore, Maria Rosaria Rizzo, Plinio Cirillo, Giuseppe Paolisso and Raffaele Marfella
    Citation: Cardiovascular Diabetology 2016 15:147
  20. Patients with diabetes are prone to develop cardiac hypertrophy and more susceptible to myocardial ischemia–reperfusion (I/R) injury, which are concomitant with hyperglycemia-induced oxidative stress and impai...

    Authors: Wating Su, Yuan Zhang, Qiongxia Zhang, Jinjin Xu, Liying Zhan, Qiqi Zhu, Qingquan Lian, Huimin Liu, Zhong-yuan Xia, Zhengyuan Xia and Shaoqing Lei
    Citation: Cardiovascular Diabetology 2016 15:146
  21. Postprandial hyperglycemia plays an important role in the pathogenesis of coronary artery disease and cardiovascular events. Serum 1,5-anhydroglucitol (1,5-AG) levels are known to be a clinical marker of postp...

    Authors: Shuhei Takahashi, Kazunori Shimada, Katsumi Miyauchi, Tetsuro Miyazaki, Eiryu Sai, Manabu Ogita, Shuta Tsuboi, Hiroshi Tamura, Shinya Okazaki, Tomoyuki Shiozawa, Shohei Ouchi, Tatsuro Aikawa, Tomoyasu Kadoguchi, Hamad Al Shahi, Takuma Yoshihara, Makoto Hiki…
    Citation: Cardiovascular Diabetology 2016 15:145
  22. Fractional flow reserve (FFR) is a widely used tool for the identification of ischaemia-generating stenoses and to guide decisions on coronary revascularisation. However, the safety of FFR-based decisions in h...

    Authors: Mark W. Kennedy, Enrico Fabris, Alexander J. Ijsselmuiden, Holger Nef, Sebastian Reith, Javier Escaned, Fernando Alfonso, Niels van Royen, Wojtek Wojakowski, Adam Witkowski, Ciro Indolfi, Jan Paul Ottervanger, Harry Suryapranata and Elvin Kedhi
    Citation: Cardiovascular Diabetology 2016 15:144
  23. Serum bicarbonate is associated with mortality, heart failure (HF) and progression of renal failure in studies of healthy people and patients with chronic kidney disease, but the significance of these observat...

    Authors: S. A. Paul Chubb, Wendy A. Davis, Kirsten E. Peters and Timothy M. E. Davis
    Citation: Cardiovascular Diabetology 2016 15:143
  24. Betatrophin has been recently reported to play a role in glucose homeostasis by inducing beta-cell proliferation in mice. However, studies in human are inconsistent. As a nutritionally-regulated liver-enriched...

    Authors: Junling Fu, Cong Hou, Lujiao Li, Dan Feng, Ge Li, Mingyao Li, Changhong Li, Shan Gao and Ming Li
    Citation: Cardiovascular Diabetology 2016 15:142
  25. The coronary risk in diabetes (CoRDia) trial (n = 211) compares the effectiveness of usual diabetes care with a self-management intervention (SMI), with and without personalised risk information (including gen...

    Authors: Katherine E. Beaney, Claire E. Ward, Dauda A. S. Bappa, Nadine McGale, Anna K. Davies, Shashivadan P. Hirani, KaWah Li, Philip Howard, Dwaine R. Vance, Martin A. Crockard, John V. Lamont, Stanton Newman and Steve E. Humphries
    Citation: Cardiovascular Diabetology 2016 15:141
  26. Type 2 diabetes mellitus (T2DM) is a recognized trigger factor for heart failure with preserved ejection fraction (HFpEF). Recent studies show that higher serum calcium level is associated with greater risk of...

    Authors: Junfeng Li, Nan Wu, Wenling Dai, Liu Jiang, Yintao Li, Shibao Li and Zhongyuan Wen
    Citation: Cardiovascular Diabetology 2016 15:140
  27. Cardiovascular disease (CVD) is one of the most common diabetes-associated complications, as well as a leading cause for death in type 2 diabetes patients (T2D). Despite the well-known correlation between the ...

    Authors: Oliver Schnell, Lars Rydén, Eberhard Standl and Antonio Ceriello
    Citation: Cardiovascular Diabetology 2016 15:139
  28. In patients with type 2 diabetes (T2D), responsiveness of serum lipid concentrations to dietary patterns may vary by genotype. The aims of the present study were to identify explorative dietary patterns and to...

    Authors: Katharina S. Weber, Birgit Knebel, Klaus Strassburger, Jörg Kotzka, Peter Stehle, Julia Szendroedi, Karsten Müssig, Anette E. Buyken and Michael Roden
    Citation: Cardiovascular Diabetology 2016 15:138
  29. Recently, genetic studies have suggested a causal relationship between cholesterol remnants and ischemic heart disease. We aimed to determine whether cholesterol remnants and its marker, triglyceride levels, a...

    Authors: Peter Godsk Jørgensen, Magnus Thorsten Jensen, Tor Biering-Sørensen, Rasmus Mogelvang, Søren Galatius, Thomas Fritz-Hansen, Peter Rossing, Tina Vilsbøll and Jan Skov Jensen
    Citation: Cardiovascular Diabetology 2016 15:137
  30. Left ventricular (LV) dysfunction is closely associated with LV hypertrophy or diabetes, as well as insufficient autophagic flux. Acute or chronic hyperglycemia is a prognostic factor for patients with myocard...

    Authors: Jiahe Xie, Kai Cui, Huixin Hao, Yingxue Zhang, Hairuo Lin, Zhenhuan Chen, Xiaobo Huang, Shiping Cao, Wangjun Liao, Jianping Bin, Masafumi Kitakaze and Yulin Liao
    Citation: Cardiovascular Diabetology 2016 15:136
  31. While most studies focus on cardiovascular morbidity following anesthesia and surgery in excessive obesity, it is unknown whether these intraoperative cardiovascular alterations also occur in milder forms of a...

    Authors: Chantal A. Boly, Etto C. Eringa, R. Arthur Bouwman, Rob F. P. van den Akker, Frances S. de Man, Ingrid Schalij, Stephan A. Loer, Christa Boer and Charissa E. van den Brom
    Citation: Cardiovascular Diabetology 2016 15:135
  32. As a sub-analysis of the PROLOGUE study, we evaluated the long-term effect of sitagliptin, a dipeptidyl peptidase 4 inhibitor, on endothelial function in the conduit brachial artery in patients with type 2 dia...

    Authors: Tatsuya Maruhashi, Yukihito Higashi, Yasuki Kihara, Hirotsugu Yamada, Masataka Sata, Shinichiro Ueda, Masato Odawara, Yasuo Terauchi, Kazuoki Dai, Jun Ohno, Masato Iida, Hiroaki Sano, Hirofumi Tomiyama, Teruo Inoue, Atsushi Tanaka, Toyoaki Murohara…
    Citation: Cardiovascular Diabetology 2016 15:134
  33. Type 2 diabetes mellitus is associated strongly with an increased risk of micro- and macro-vascular complications, leading to impaired quality of life and shortened life expectancy. In addition to appropriate ...

    Authors: Atsushi Tanaka, Toyoaki Murohara, Isao Taguchi, Kazuo Eguchi, Makoto Suzuki, Masafumi Kitakaze, Yasunori Sato, Tomoko Ishizu, Yukihito Higashi, Hirotsugu Yamada, Mamoru Nanasato, Michio Shimabukuro, Hiroki Teragawa, Shinichiro Ueda, Satoshi Kodera, Munehide Matsuhisa…
    Citation: Cardiovascular Diabetology 2016 15:133
  34. Angiopoietin-like protein 3 (ANGPTL3) is a major lipoprotein regulator and shows positive correlation with high-density lipoprotein-cholesterol (HDL-c) in population studies and ANGPTL3 mutated subjects. Howev...

    Authors: Dong Zhao, Long-Yan Yang, Xu-Hong Wang, Sha-Sha Yuan, Cai-Guo Yu, Zong-Wei Wang, Jia-Nan Lang and Ying-Mei Feng
    Citation: Cardiovascular Diabetology 2016 15:132
  35. We aimed to investigate the mortality rate (MR), causes of death and standardized mortality ratio (SMR) in Korean type 2 diabetic patients from 2002 to 2013 using data from the Korean National Health Insurance...

    Authors: Yu Mi Kang, Ye-Jee Kim, Joong-Yeol Park, Woo Je Lee and Chang Hee Jung
    Citation: Cardiovascular Diabetology 2016 15:131
  36. An emerging treatment modality for reducing damage caused by ischaemia–reperfusion injury is ischaemic conditioning. This technique induces short periods of ischaemia that have been found to protect against a ...

    Authors: J. A. Epps and N. A. Smart
    Citation: Cardiovascular Diabetology 2016 15:130
  37. Peripheral arterial disease (PAD) is known to be associated with high cardiovascular risk, but the individual impact of PAD presentations on risk of macrovascular and microvascular events has not been reliably...

    Authors: Kamel Mohammedi, Mark Woodward, Yoichiro Hirakawa, Sophia Zoungas, Stephen Colagiuri, Pavel Hamet, Stephen Harrap, Neil Poulter, David R. Matthews, Michel Marre and John Chalmers
    Citation: Cardiovascular Diabetology 2016 15:129
  38. Vitamin D status has been hypothesized to protect against development of diabetic retinopathy via its anti-inflammatory and anti-angiogenic properties. Additionally, in vitro and in vivo studies suggest vitami...

    Authors: Amy E. Millen, Michelle W. Sahli, Jing Nie, Michael J. LaMonte, Pamela L. Lutsey, Barbara E. K. Klein, Julie A. Mares, Kirstin J. Meyers, Christopher A. Andrews and Ronald Klein
    Citation: Cardiovascular Diabetology 2016 15:128
  39. We aimed to analyze the relationships between skin autofluorescence (SAF) and incident macrovascular events and renal impairment after 4 years of follow-up in patients with type 1 diabetes (T1D).

    Authors: Fritz-Line Vélayoudom-Céphise, Kalina Rajaobelina, Catherine Helmer, Sovanndany Nov, Emilie Pupier, Laurence Blanco, Marie Hugo, Blandine Farges, Cyril Astrugue, Henri Gin and Vincent Rigalleau
    Citation: Cardiovascular Diabetology 2016 15:127
  40. Although increased oxidative stress is a major component of diabetic hypertensive cardiomyopathy, research into the effects of antioxidants on cardiac remodeling remains scarce. The actions of antioxidant apoc...

    Authors: C. M. Rosa, R. Gimenes, D. H. S. Campos, G. N. Guirado, C. Gimenes, A. A. H. Fernandes, A. C. Cicogna, R. M. Queiroz, I. Falcão-Pires, D. Miranda-Silva, P. Rodrigues, F. R. Laurindo, D. C. Fernandes, C. R. Correa, M. P. Okoshi and K. Okoshi
    Citation: Cardiovascular Diabetology 2016 15:126
  41. Pleiotropic effects on cardiovascular protection have been suggested in several oral antidiabetic drugs (OAD). The impacts of OADs on aortic aneurysm (AA) growth have been found in animal studies, but the evid...

    Authors: Chien-Yi Hsu, Yu-Wen Su, Yung-Tai Chen, Shih-Hung Tsai, Chun-Chin Chang, Szu-Yuan Li, Po-Hsun Huang, Jaw-Wen Chen and Shing-Jong Lin
    Citation: Cardiovascular Diabetology 2016 15:125
  42. Improved outcomes in patients with diabetes mellitus undergoing percutaneous coronary intervention remain an unmet clinical need. We assessed the long-term efficacy and safety of novel polymer-free sirolimus- ...

    Authors: Yukinori Harada, Roisin Colleran, Sebastian Kufner, Daniele Giacoppo, Tobias Rheude, Jonathan Michel, Salvatore Cassese, Tareq Ibrahim, Karl-Ludwig Laugwitz, Adnan Kastrati and Robert A. Byrne
    Citation: Cardiovascular Diabetology 2016 15:124
  43. Increased levels of glucagon in type 2 diabetes are well known and, until now, have been considered deleterious. However, glucagon has an important role in the maintenance of both heart and kidney function. Mo...

    Authors: Antonio Ceriello, Stefano Genovese, Edoardo Mannucci and Edoardo Gronda
    Citation: Cardiovascular Diabetology 2016 15:123
  44. Acid–base imbalance has been reported to increase incidence of hypertension and diabetes. However, the association between diet-induced acid load and cardiovascular disease (CVD) risk in the general population...

    Authors: Eugene Han, Gyuri Kim, Namki Hong, Yong-ho Lee, Dong Woo Kim, Hyun Joon Shin, Byung-Wan Lee, Eun Seok Kang, In-Kyu Lee and Bong-Soo Cha
    Citation: Cardiovascular Diabetology 2016 15:122
  45. Recent experimental studies have revealed that n-3 fatty acids, such as eicosapentaenoic acid (EPA) regulate postprandial insulin secretion, and correct postprandial glucose and lipid abnormalities. However, t...

    Authors: Takahiro Sawada, Hideo Tsubata, Naoko Hashimoto, Michinori Takabe, Taishi Miyata, Kosuke Aoki, Soichiro Yamashita, Shogo Oishi, Tsuyoshi Osue, Kiminobu Yokoi, Yasue Tsukishiro, Tetsuari Onishi, Akira Shimane, Yasuyo Taniguchi, Yoshinori Yasaka, Takeshi Ohara…
    Citation: Cardiovascular Diabetology 2016 15:121
  46. The metabolic syndrome is becoming increasingly prevalent in the general population that is at simultaneous risk for both type 2 diabetes and cardiovascular disease. The critical pathogenic mechanisms underlyi...

    Authors: V. Moreno-Viedma, M. Amor, A. Sarabi, M. Bilban, G. Staffler, M. Zeyda and T. M. Stulnig
    Citation: Cardiovascular Diabetology 2016 15:120
  47. Type 1 diabetes is associated with increased cardiovascular disease (CVD). Decreased endothelial progenitor cells (EPCs) number plays a pivotal role in reduced endothelial repair and development of CVD. We aim...

    Authors: Fahad W. Ahmed, Rachel Rider, Michael Glanville, Kilimangalam Narayanan, Salman Razvi and Jolanta U. Weaver
    Citation: Cardiovascular Diabetology 2016 15:116
  48. High fat diet (HFD) induces insulin resistance in various tissues, including the vasculature. HFD also increases plasma levels of TNF-α, a cytokine that contributes to insulin resistance and vascular dysfuncti...

    Authors: Rafael Menezes da Costa, Karla Bianca Neves, Fabíola Leslie Mestriner, Paulo Louzada-Junior, Thiago Bruder-Nascimento and Rita C. Tostes
    Citation: Cardiovascular Diabetology 2016 15:119
  49. We intended to analyse the associations between blood glucose (BG) level and clinical outcomes of in-hospital cardiac arrest (IHCA).

    Authors: Chih-Hung Wang, Chien-Hua Huang, Wei-Tien Chang, Min-Shan Tsai, Ping-Hsun Yu, Yen-Wen Wu and Wen-Jone Chen
    Citation: Cardiovascular Diabetology 2016 15:118
  50. Chemokines are critical components in pathology. The roles of chemokine CC motif ligand 4 (CCL4) and its receptor are associated with diabetes mellitus (DM) and atherosclerosis cardiovascular diseases. However...

    Authors: Ting-Ting Chang and Jaw-Wen Chen
    Citation: Cardiovascular Diabetology 2016 15:117

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