Skip to main content

Articles

Page 33 of 37

  1. Glucagon-like peptide-1 (GLP-1) is an incretin hormone that has a wide range of effects on glucose metabolism and cardiovascular function (e.g., improving insulin sensitivity, reduction in appetite, modulation...

    Authors: Minako Yamaoka-Tojo, Taiki Tojo, Naonobu Takahira, Atsuhiko Matsunaga, Naoyoshi Aoyama, Takashi Masuda and Tohru Izumi

    Citation: Cardiovascular Diabetology 2010 9:17

    Content type: Original investigation

    Published on:

  2. To evaluate glycemic variability associated with two different premixed insulin analogue formulations when used in a twice-daily regimen.

    Authors: Rimei Nishimura, Daisuke Tsujino, Kentaro Taki, Aya Morimoto and Naoko Tajima

    Citation: Cardiovascular Diabetology 2010 9:16

    Content type: Original investigation

    Published on:

  3. Although there is a growing body of evidence showing that patients with type 2 diabetes mellitus (T2DM) have poor glycemic control in general, it is not clear whether T2DM patients with pre-existing cardiovasc...

    Authors: Alex Z Fu, Ying Qiu, Larry Radican, Donald D Yin and Panagiotis Mavros

    Citation: Cardiovascular Diabetology 2010 9:15

    Content type: Original investigation

    Published on:

  4. Many studies on diabetes have demonstrated that an intensive control of glycaemia and the main associated risk factors (hypertension, dislipidaemia, obesity and smoking) reduce cardiovascular morbi-mortality. ...

    Authors: Lucas Mengual, Pilar Roura, Marta Serra, Montserrat Montasell, Gemma Prieto and Sandra Bonet

    Citation: Cardiovascular Diabetology 2010 9:14

    Content type: Original investigation

    Published on:

  5. Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor, which regulates gene expression of the key proteins involved in lipid metabolism, vascular inflammation, and pro...

    Authors: Jing Wan, Shixi Xiong, Shengping Chao, Jianming Xiao, Yexin Ma, Jinghua Wang and Sabita Roy

    Citation: Cardiovascular Diabetology 2010 9:13

    Content type: Original investigation

    Published on:

  6. Postprandial hyperglycemia is believed to affect vascular endothelial function. The aim of our study was to compare the effects of acarbose and nateglinide on postprandial endothelial dysfunction.

    Authors: Toru Kato, Teruo Inoue and Koichi Node

    Citation: Cardiovascular Diabetology 2010 9:12

    Content type: Original investigation

    Published on:

  7. The metabolic syndrome is thought to be associated with a chronic low-grade inflammation, and a growing body of evidence suggests that interleukin-18 (IL-18) might be closely related to the metabolic syndrome ...

    Authors: Marius Trøseid, Ingebjørg Seljeflot and Harald Arnesen

    Citation: Cardiovascular Diabetology 2010 9:11

    Content type: Review

    Published on:

  8. Adiponectin is an adipose tissue secreted protein known for its insulin sensitising and anti-atherogenic actions. To this date two adiponectin receptors have been discovered, adiponectin receptor 1 (ADIPOR1) a...

    Authors: Iosif Halvatsiotis, Panayoula C Tsiotra, Ignatios Ikonomidis, Anastasios Kollias, Panagiota Mitrou, Eirini Maratou, Eleni Boutati, John Lekakis, George Dimitriadis, Theofanis Economopoulos, Dimitrios T Kremastinos and Sotirios A Raptis

    Citation: Cardiovascular Diabetology 2010 9:10

    Content type: Original investigation

    Published on:

  9. CVD in obesity and T2DM are associated with endothelial activation, elevated plasma vascular inflammation markers and a prothrombotic state. We examined the contribution of FFA to these abnormalities following...

    Authors: Manoj Mathew, Eric Tay and Kenneth Cusi

    Citation: Cardiovascular Diabetology 2010 9:9

    Content type: Original investigation

    Published on:

  10. Diminished calcium (Ca2+) transients in response to physiological agonists have been reported in vascular smooth muscle cells (VSMCs) from diabetic animals. However, the mechanism responsible was unclear.

    Authors: Yvonne M Searls, Rajprasad Loganathan, Irina V Smirnova and Lisa Stehno-Bittel

    Citation: Cardiovascular Diabetology 2010 9:8

    Content type: Original investigation

    Published on:

  11. This cross-sectional study sought to determine the prevalence of cardiometabolic risk factor clusters (CMRFCs) and their effect on BP control among hypertensive patients from 28 US physician practices.

    Authors: Daniel A Belletti, Christopher Zacker and Jenifer Wogen

    Citation: Cardiovascular Diabetology 2010 9:7

    Content type: Original investigation

    Published on:

  12. Cardiovascular effects of glucose-lowering agents are of increasing interest. Our aim was to assess the effects of the glucagon-like peptide-1 receptor agonist exenatide on heart rate (HR) and blood pressure (...

    Authors: Anne Gill, Byron J Hoogwerf, Jude Burger, Simon Bruce, Leigh MacConell, Ping Yan, Daniel Braun, Joseph Giaconia and James Malone

    Citation: Cardiovascular Diabetology 2010 9:6

    Content type: Original investigation

    Published on:

  13. Diabetes is associated with changes in myocardial stress-response pathways and is recognized as an independent risk factor for cardiac remodeling. Using spontaneously diabetic Goto Kakizaki rats as a model of ...

    Authors: Erik Vahtola, Marjut Louhelainen, Hanna Forstén, Saara Merasto, Johanna Raivio, Petri Kaheinen, Ville Kytö, Ilkka Tikkanen, Jouko Levijoki and Eero Mervaala

    Citation: Cardiovascular Diabetology 2010 9:5

    Content type: Original investigation

    Published on:

  14. The aim of this study was to determine whether South Asian patients with diabetes have a worse prognosis following hospitalization for acute myocardial infarction (AMI) compared with their White counterparts. ...

    Authors: Aman PK Nijjar, Hong Wang, Kaberi Dasgupta, Doreen M Rabi, Hude Quan and Nadia A Khan

    Citation: Cardiovascular Diabetology 2010 9:4

    Content type: Original investigation

    Published on:

  15. Patients with diabetes mellitus (DM) have high risk of heart failure. Whether some of the risk is directly linked to metabolic derangements in the myocardium or whether the risk is primarily caused by coronary...

    Authors: Charlotte Andersson, Gunnar H Gislason, Peter Weeke, Søren Hoffmann, Peter R Hansen, Christian Torp-Pedersen and Peter Søgaard

    Citation: Cardiovascular Diabetology 2010 9:3

    Content type: Original investigation

    Published on:

  16. The aims of this study were to estimate the prevalence of left ventricular systolic (LVSD) and diastolic (LVDD) dysfunction, and to test if BNP and urinary albumin excretion rate (AER) are related to LVSD, LVD...

    Authors: Martin Magnusson, Stefan Jovinge, Kambiz Shahgaldi, Bo Israelsson, Leif Groop and Olle Melander

    Citation: Cardiovascular Diabetology 2010 9:2

    Content type: Original investigation

    Published on:

  17. The long-term prognosis of diabetic patients with acute myocardial infarction (AMI) treated by acute revascularization is uncertain, and the optimal pharmacotherapy for such cases has not been fully evaluated.

    Authors: Ayako Takara, Hiroshi Ogawa, Yasuhiro Endoh, Fumiaki Mori, Jun-ichi Yamaguchi, Atsushi Takagi, Ryo Koyanagi, Tsuyoshi Shiga, Hiroshi Kasanuki and Nobuhisa Hagiwara

    Citation: Cardiovascular Diabetology 2010 9:1

    Content type: Original investigation

    Published on:

  18. Dysfunctionally uncoupled endothelial nitric oxide synthase (eNOS) is involved in producing reactive oxygen species (ROS) in the diabetic endothelium. The present study investigated whether anti-diabetes drug ...

    Authors: Jeong-Ho Oak, Ji-Youn Youn and Hua Cai

    Citation: Cardiovascular Diabetology 2009 8:65

    Content type: Original investigation

    Published on:

  19. Vascular smooth muscular cells (VSMC) express lipogenic genes. Therefore in situ lipogenesis could provide fatty acids for triglycerides synthesis and cholesterol esterification and contribute to lipid accumulati...

    Authors: Nadjiba Hamlat, Fabien Forcheron, Samia Negazzi, Peggy del Carmine, Patrick Feugier, Giampiero Bricca, Souhila Aouichat-Bouguerra and Michel Beylot

    Citation: Cardiovascular Diabetology 2009 8:64

    Content type: Original investigation

    Published on:

  20. Hepatocyte nuclear factor 4α (HNF4α) is a nuclear receptor involved in glucose homeostasis and is required for normal β cell function. Mutations in the HNF4α gene are associated with maturity onset diabetes of...

    Authors: Seyed Morteza Taghavi, Seyedeh Seddigheh Fatemi, Houshang Rafatpanah, Rashin Ganjali, Jalil Tavakolafshari and Narges Valizadeh

    Citation: Cardiovascular Diabetology 2009 8:63

    Content type: Original investigation

    Published on:

  21. Patients with obesity, diabetes, and chronic kidney disease (CKD) are generally physically inactive, have a high mortality rate, and may benefit from an exercise program.

    Authors: David J Leehey, Irfan Moinuddin, Joseph P Bast, Shahzad Qureshi, Christine S Jelinek, Cheryl Cooper, Lonnie C Edwards, Bridget M Smith and Eileen G Collins

    Citation: Cardiovascular Diabetology 2009 8:62

    Content type: Original investigation

    Published on:

  22. Resistin, secreted from adipocytes, causes insulin resistance in mice. The relationship between resistin and coronary artery disease is highly controversial, and the information regarding resistin and ischemic...

    Authors: Haruhiko Osawa, Yasufumi Doi, Hideichi Makino, Toshiharu Ninomiya, Koji Yonemoto, Ryoichi Kawamura, Jun Hata, Yumihiro Tanizaki, Mitsuo Iida and Yutaka Kiyohara

    Citation: Cardiovascular Diabetology 2009 8:60

    Content type: Original investigation

    Published on:

  23. A large number of people throughout the world have diabetes and the prevalence is increasing. Persons with diabetes have a twice higher risk of cardiovascular disease than those without diabetes. There is a la...

    Authors: Marina Taloyan, Alexandre Wajngot, Sven-Erik Johansson, Jonas Tovi and Jan Sundquist

    Citation: Cardiovascular Diabetology 2009 8:59

    Content type: Original investigation

    Published on:

  24. Diabetes mellitus (DM) has reached epidemic proportions and is an important risk factor for heart failure (HF). Left ventricular diastolic dysfunction (LVDD) is recognized as the earliest manifestation of DM-i...

    Authors: Wilfried Dinh, Reiner Füth, Werner Nickl, Thomas Krahn, Peter Ellinghaus, Thomas Scheffold, Lars Bansemir, Alexander Bufe, Michael Coll Barroso and Mark Lankisch

    Citation: Cardiovascular Diabetology 2009 8:58

    Content type: Original investigation

    Published on:

  25. The risk-benefit ratio of aspirin therapy in prevention of cardiovascular disease (CVD) remains contentious, especially in type 2 diabetes. This study examined the benefit and harm of low-dose aspirin (daily d...

    Authors: Wilson Y Leung, Wing-yee So, Derek Stewart, Augustine Lui, Peter C Tong, Gary T Ko, Alice P Kong, Ronald C Ma, Francis K Chan, Xilin Yang, Sau-chu Chiang and Juliana C Chan

    Citation: Cardiovascular Diabetology 2009 8:57

    Content type: Original investigation

    Published on:

  26. The function of endothelial progenitor cells (EPCs), which are key cells in vascular repair, is impaired in diabetes mellitus. Nitric oxide (NO) and reactive oxygen species can regulate EPC functions. EPCs tol...

    Authors: Saher Hamed, Benjamin Brenner, Anat Aharon, Deeb Daoud and Ariel Roguin

    Citation: Cardiovascular Diabetology 2009 8:56

    Content type: Original investigation

    Published on:

  27. Increased resting heart rate (RHR) may be associated with increased cardiovascular morbidity. Our aim was to explore the possibility that increased RHR is associated with the prevalence of the metabolic syndro...

    Authors: Ori Rogowski, Arie Steinvil, Shlomo Berliner, Michael Cohen, Nili Saar, Orit Kliuk Ben-Bassat and Itzhak Shapira

    Citation: Cardiovascular Diabetology 2009 8:55

    Content type: Original investigation

    Published on:

  28. Cardiovascular disease is the main cause of premature death in patients with type 1 diabetes. Patients with diabetic kidney disease have an increased risk of heart attack or stroke. Accurate knowledge of the c...

    Authors: Ville-Petteri Mäkinen, Carol Forsblom, Lena M Thorn, Johan Wadén, Kimmo Kaski, Mika Ala-Korpela and Per-Henrik Groop

    Citation: Cardiovascular Diabetology 2009 8:54

    Content type: Original investigation

    Published on:

  29. Patients with type 2 diabetes are at increased risk of cardiovascular events, and there is an associated economic burden attached to this risk. We conducted a retrospective claims database analysis to evaluate...

    Authors: Robert J Straka, Larry Z Liu, Prafulla S Girase, Allyson DeLorenzo and Richard H Chapman

    Citation: Cardiovascular Diabetology 2009 8:53

    Content type: Original investigation

    Published on:

  30. Metabolic syndrome increases cardiovascular risk. Limited information on its prevalence in Latin America is available. The Cardiovascular Risk Factor Multiple Evaluation in Latin America (CARMELA) study includ...

    Authors: Jorge Escobedo, Herman Schargrodsky, Beatriz Champagne, Honorio Silva, Carlos P Boissonnet, Raul Vinueza, Marta Torres, Rafael Hernandez and Elinor Wilson

    Citation: Cardiovascular Diabetology 2009 8:52

    Content type: Original investigation

    Published on:

  31. The GOOD (Global Cardiometabolic Risk Profile in Patients with Hypertension Disease) survey showed that blood pressure control was significantly worse in hypertensive patients with metabolic syndrome and/or di...

    Authors: Walter Zidek, Lisa Naditch-Brûlé, Stefano Perlini, Csaba Farsang and Sverre E Kjeldsen

    Citation: Cardiovascular Diabetology 2009 8:51

    Content type: Original investigation

    Published on:

  32. Myocardial infarction results as a consequence of atherosclerotic plaque rupture, with plaque stability largely depending on the lesion forming extracellular matrix components. Lipid enriched non-calcified les...

    Authors: Michael Lehrke, Martin Greif, Uli C Broedl, Corinna Lebherz, Rüdiger P Laubender, Alexander Becker, Franz von Ziegler, Janine Tittus, Maximilian Reiser, Christoph Becker, Burkhard Göke, Gerhard Steinbeck, Alexander W Leber and Klaus G Parhofer

    Citation: Cardiovascular Diabetology 2009 8:50

    Content type: Original investigation

    Published on:

  33. Type 2 diabetes mellitus (T2DM) is commonly associated with both microvascular and macrovascular complications and a strong correlation exists between glycaemic control and the incidence and progression of vas...

    Authors: Federico Biscetti, Giuseppe Straface, Vincenzo Arena, Egidio Stigliano, Giovanni Pecorini, Paola Rizzo, Giulia De Angelis, Luigi Iuliano, Giovanni Ghirlanda and Andrea Flex

    Citation: Cardiovascular Diabetology 2009 8:49

    Content type: Original investigation

    Published on:

  34. Thrombosis is regarded to be a key factor in the development of acute coronary syndromes in patients with coronary artery disease (CAD). We hypothesize, that hemostatic and rheological risk factors may be of m...

    Authors: Thomas W Jax, Ansgar J Peters, Gunnar Plehn and Frank-Chris Schoebel

    Citation: Cardiovascular Diabetology 2009 8:48

    Content type: Original investigation

    Published on:

  35. Endothelial progenitor cells play an important role in vascular wall repair. Patients with type 1 diabetes have reduced levels of endothelial progenitor cells of which their functional capacity is impaired. Re...

    Authors: Olivia van Oostrom, Dominique PV de Kleijn, Joost O Fledderus, Mario Pescatori, Andrew Stubbs, Attie Tuinenburg, Sai Kiang Lim and Marianne C Verhaar

    Citation: Cardiovascular Diabetology 2009 8:47

    Content type: Original investigation

    Published on:

  36. Heparan sulfate proteoglycans (HSPGs) contain glycosaminoglycan (GAG) chains made primarily of heparan sulfate (HS). Hyperglycemia in diabetes leads to endothelial injury and nephropathy, retinopathy and ather...

    Authors: Juying Han, Fuming Zhang, Jin Xie, Robert J Linhardt and Linda M Hiebert

    Citation: Cardiovascular Diabetology 2009 8:46

    Content type: Original investigation

    Published on:

  37. Nε-Carboxymethyllysine (CML) is the major non-cross linking advanced glycation end product (AGE). CML is elevated in diabetic patients and apparent in atherosclerotic lesions. AGEs are associated with hypertensi....

    Authors: Marcus Baumann, Tom Richart, Daniel Sollinger, Jaroslav Pelisek, Marcel Roos, Tatiana Kouznetsova, Hans-Henning Eckstein, Uwe Heemann and Jan A Staessen

    Citation: Cardiovascular Diabetology 2009 8:45

    Content type: Original investigation

    Published on:

  38. All previous studies that investigated the association between abdominal fat distribution and insulin resistance evaluated subcutaneous and visceral fat area and/or volume, but these values were not related to...

    Authors: Yoshinori Miyazaki and Ralph A DeFronzo

    Citation: Cardiovascular Diabetology 2009 8:44

    Content type: Original investigation

    Published on:

  39. Maternal diabetes affects the developing fetal cardiovascular system. Newborn offspring of diabetic mothers can have a transient cardiomyopathy. We hypothesized that cardiomyopathic remodeling is associated wi...

    Authors: Benjamin E Reinking, Elesa W Wedemeyer, Robert M Weiss, Jeffrey L Segar and Thomas D Scholz

    Citation: Cardiovascular Diabetology 2009 8:43

    Content type: Original investigation

    Published on:

  40. White adipose tissue (WAT) is a disperse organ acting as energy storage depot and endocrine/paracrine controlling factor in the management of energy availability and inflammation. WAT sites response under ener...

    Authors: María del Mar Romero, José Antonio Fernández-López, Montserrat Esteve and Marià Alemany

    Citation: Cardiovascular Diabetology 2009 8:42

    Content type: Original investigation

    Published on:

  41. The prevalence of diabetes is increasing rapidly, and individuals with diabetes are at high risk for cardiovascular disorders. Subsequently the percentage of patients with diabetes subjected to revascularisati...

    Authors: Chris PH Lexis, Braim M Rahel, Joan G Meeder, Felix Zijlstra and Iwan CC van der Horst

    Citation: Cardiovascular Diabetology 2009 8:41

    Content type: Review

    Published on:

  42. A meta-analysis suggested the use of rosiglitazone was associated with an increased risk for cardiovascular (CV) events. Rosiglitazone remained available for use as more definitive safety trials were ongoing. ...

    Authors: Doreen M Rabi, Adriane M Lewin, Garielle E Brown, Alun L Edwards, Jeffrey A Johnson and William A Ghali

    Citation: Cardiovascular Diabetology 2009 8:40

    Content type: Review

    Published on:

  43. In vitro data suggest that changes in myocardial substrate metabolism may contribute to impaired myocardial function in diabetic cardiomyopathy (DCM). The purpose of the present study was to study in a rat model ...

    Authors: Charissa E van den Brom, Marc C Huisman, Ronald Vlasblom, Nicky M Boontje, Suzanne Duijst, Mark Lubberink, Carla FM Molthoff, Adriaan A Lammertsma, Jolanda van der Velden, Christa Boer, D Margriet Ouwens and Michaela Diamant

    Citation: Cardiovascular Diabetology 2009 8:39

    Content type: Original investigation

    Published on:

  44. Bariatric surgery is able to improve glucose and lipid metabolism, and cardiovascular function in morbid obesity. Aim of this study was to compare the long-term effects of malabsorptive (biliary pancreatic div...

    Authors: Antonio E Pontiroli, Marco Laneri, Annamaria Veronelli, Francesca Frigè, Giancarlo Micheletto, Franco Folli, Gianfranco Adami and Nicola Scopinaro

    Citation: Cardiovascular Diabetology 2009 8:37

    Content type: Original investigation

    Published on:

  45. We investigated whether macronutrient composition of energy-restricted diets influences the efficacy of a telemedically guided weight loss program.

    Authors: Sabine Frisch, Armin Zittermann, Heiner K Berthold, Christian Götting, Joachim Kuhn, Knut Kleesiek, Peter Stehle and Heinrich Körtke

    Citation: Cardiovascular Diabetology 2009 8:36

    Content type: Original investigation

    Published on:

  46. Our aim was to compare the effects of a Paleolithic ('Old Stone Age') diet and a diabetes diet as generally recommended on risk factors for cardiovascular disease in patients with type 2 diabetes not treated w...

    Authors: Tommy Jönsson, Yvonne Granfeldt, Bo Ahrén, Ulla-Carin Branell, Gunvor Pålsson, Anita Hansson, Margareta Söderström and Staffan Lindeberg

    Citation: Cardiovascular Diabetology 2009 8:35

    Content type: Original investigation

    Published on:

  47. Few studies have assessed secular changes in the levels of cardiovascular risk factors (CV-RF) in populations of low or middle income countries. The systematic collection of a broad set of both traditional and...

    Authors: Pascal Bovet, Sarah Romain, Conrad Shamlaye, Shanti Mendis, Roger Darioli, Walter Riesen, Luc Tappy and Fred Paccaud

    Citation: Cardiovascular Diabetology 2009 8:34

    Content type: Original investigation

    Published on:

  48. Both obesity and type 2 diabetes are among the risk factors for breast cancer development. Combined effect of these metabolic abnormalities on breast cancer risk however, has not been examined in premenopausal...

    Authors: Majed S Alokail, Nasser M Al-Daghri, Omar S Al-Attas and Tajamul Hussain

    Citation: Cardiovascular Diabetology 2009 8:33

    Content type: Original investigation

    Published on:

Annual Journal Metrics