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  1. An intergenic locus on chromosome 1 (lead SNP rs10911021) was previously associated with coronary heart disease (CHD) in type 2 diabetes (T2D). Using data from the UCLEB consortium we investigated the relation...

    Authors: Katherine E. Beaney, Jackie A. Cooper, Stela McLachlan, S. Goya Wannamethee, Barbara J. Jefferis, Peter Whincup, Yoav Ben-Shlomo, Jacqueline F. Price, Meena Kumari, Andrew Wong, Ken Ong, Rebecca Hardy, Diana Kuh, Mika Kivimaki, Antti J. Kangas, Pasi Soininen…
    Citation: Cardiovascular Diabetology 2016 15:115
  2. Chronic stress is associated with increased risk of glucose intolerance and cardiovascular diseases, albeit through undefined mechanisms. With the aim of gaining insights into the latter, this study examined t...

    Authors: Vitor H. Pereira, Fernanda Marques, Vânia Lages, Filipa G. Pereira, Alexandre Patchev, Osborne F. X. Almeida, Joana Almeida-Palha, Nuno Sousa and João J. Cerqueira
    Citation: Cardiovascular Diabetology 2016 15:114
  3. Despite the known risk of diabetes-induced cardiac fibrosis, less is known about whether diabetes causes an altered cardiac phenotype independent of coronary atherosclerosis. Peroxisome proliferator-activated ...

    Authors: Wei-Ting Chang, Juei-Tang Cheng and Zhih-Cherng Chen
    Citation: Cardiovascular Diabetology 2016 15:113
  4. There are conflicting results for relationships between serum vitamin D levels and metabolic diseases. The aim of this study was to investigate whether serum vitamin D levels were associated with various metab...

    Authors: Ki-Chul Sung, Yoosoo Chang, Seungho Ryu and Hye-Kyung Chung
    Citation: Cardiovascular Diabetology 2016 15:112
  5. Diabetic patients suffer from a high rate of cardiovascular events and such risk increases with HbA1c. However, lowering HbA1c does not appear to yield the same benefit on macrovascular endpoints, as observed ...

    Authors: Angelo Avogaro, Gian Paolo Fadini, Giorgio Sesti, Enzo Bonora and Stefano Del Prato
    Citation: Cardiovascular Diabetology 2016 15:111
  6. There is a spectacular rise in the global prevalence of type 2 diabetes mellitus (T2DM) due to the worldwide obesity epidemic. However, a significant proportion of T2DM patients are non-obese and they also hav...

    Authors: Márta Sárközy, Gergő Szűcs, Veronika Fekete, Márton Pipicz, Katalin Éder, Renáta Gáspár, Andrea Sója, Judit Pipis, Péter Ferdinandy, Csaba Csonka and Tamás Csont
    Citation: Cardiovascular Diabetology 2016 15:110
  7. Complications of diabetes mellitus (DM) are related not only to elevated plasma glucose, but also plasma glucose fluctuations. However, the specific mechanism underlying the role of plasma glucose fluctuation ...

    Authors: Na Wu, Haitao Shen, Henan Liu, Yanjun Wang, Yu Bai and Ping Han
    Citation: Cardiovascular Diabetology 2016 15:109
  8. This study investigated the association between serum gamma-glutamyltransferase (GGT) level and subclinical atherosclerosis in patients with type 2 diabetes.

    Authors: Hye Eun Yoon, Eun Young Mo, Seok Joon Shin, Sung Dae Moon, Je Ho Han and Eun Sook Kim
    Citation: Cardiovascular Diabetology 2016 15:108
  9. PCSK9 inhibition is a new powerful cholesterol-lowering strategy. Recently, it was reported that CETP inhibitors influence PCSK9 levels as an off-target effect. We explored the relationship between circulating...

    Authors: Josefa Girona, Daiana Ibarretxe, Nuria Plana, Sandra Guaita-Esteruelas, Nuria Amigo, Mercedes Heras and Luis Masana
    Citation: Cardiovascular Diabetology 2016 15:107
  10. We try to analyse the effect of renal functions on death in CAD patients with different body compositions.

    Authors: Yong Peng, Hua Wang, Fei Chen, Fang-yang Huang, Tian-li Xia, Yan-biao Liao, Hua Chai, Peng-ju Wang, Zhi-liang Zuo, Wei Liu, Chen Zhang, Yi-jian Li, Yi-yue Gui, Mao Chen and De-jia Huang
    Citation: Cardiovascular Diabetology 2016 15:106
  11. Patients with type 2 diabetes (T2D) and coronary artery disease (CAD) have increased risk of cardiac dysfunction. The diabetic heart is characterized by increased fatty acid oxidation and reduced glucose uptak...

    Authors: Preman Kumarathurai, Christian Anholm, Olav W. Nielsen, Ole P. Kristiansen, Jens Mølvig, Sten Madsbad, Steen B. Haugaard and Ahmad Sajadieh
    Citation: Cardiovascular Diabetology 2016 15:105
  12. To investigate whether atherogenic dyslipidemia, a dyslipidemic profile combining elevated triglycerides and low high-density lipoprotein (HDL) cholesterol, is predictive of risk of silent myocardial ischemia ...

    Authors: Paul Valensi, Antoine Avignon, Ariane Sultan, Bernard Chanu, Minh Tuan Nguyen and Emmanuel Cosson
    Citation: Cardiovascular Diabetology 2016 15:104
  13. Authors: Ana Lopez-de-Andrés, Isabel Jiménez-Trujillo, Rodrigo Jiménez-García, Valentín Hernández-Barrera, José Mª de Miguel-Yanes, Manuel Méndez-Bailón, Napoleón Perez-Farinos, Miguel Ángel Salinero-Fort and Pilar Carrasco-Garrido
    Citation: Cardiovascular Diabetology 2016 15:103

    The original article was published in Cardiovascular Diabetology 2015 14:48

  14. The prevalence of type 2 diabetes (T2DM) in younger adults is growing. Compared to the late onset T2DM, it is well recognized that the disease tends to behave more aggressively in the younger age group with ev...

    Authors: Z. Z. Htike, T. Yates, E. M. Brady, D. Webb, L. J. Gray, D. Swarbrick, G. P. McCann, K. Khunti and M. J. Davies
    Citation: Cardiovascular Diabetology 2016 15:102
  15. Strict glycaemic control in patients with type 2 diabetes has proven to have microvascular benefits while the effects on CVD and mortality are less clear, especially in high risk patients. Whether strict glyca...

    Authors: Sophie H. Bots, Yolanda van der Graaf, Hendrik M. W. Nathoe, Gert Jan de Borst, Jaap L. Kappelle, Frank L. J. Visseren and Jan Westerink
    Citation: Cardiovascular Diabetology 2016 15:101
  16. Deferred revascularisation based upon fractional flow reserve (FFR >0.80) is associated with a low incidence of target lesion failure (TLF). Whether deferred revascularisation is also as safe in diabetes melli...

    Authors: Mark W. Kennedy, Eliza Kaplan, Rik S. Hermanides, Enrico Fabris, Veemal Hemradj, Petra C. Koopmans, Jan-Hank E. Dambrink, A. T. Marcel Gosselink, Arnoud W. J. van‘t Hof, Jan Paul Ottervanger, Vincent Roolvink, Wouter S. Remkes, Aize van der Sluis, Harry Suryapranata and Elvin Kedhi
    Citation: Cardiovascular Diabetology 2016 15:100
  17. Glucagon-like peptide-1 (7–36) amide (GLP-1) protects against stunning and cumulative left ventricular dysfunction in humans. The mechanism remains uncertain but GLP-1 may act by opening mitochondrial K-ATP ch...

    Authors: Joel P. Giblett, Richard G. Axell, Paul A. White, Sophie J. Clarke, Liam McCormick, Philip A. Read, Johannes Reinhold, Adam J. Brown, Michael O’Sullivan, Nick E. J. West, David P. Dutka and Stephen P. Hoole
    Citation: Cardiovascular Diabetology 2016 15:99
  18. Diabetes mellitus (DM) is associated to the morphological and componential characteristics of atheromatous plaques. It has proven that plaque textures are related to plaque components and beneficial for athero...

    Authors: Xiao-Wei Huang, Yan-Ling Zhang, Long Meng, Ming Qian, Wei Zhou, Rong-Qin Zheng, Hai-Rong Zheng and Li–Li Niu
    Citation: Cardiovascular Diabetology 2016 15:98
  19. Heart failure (HF) and diabetes (DM) are a lethal combination. The current armamentarium of anti-diabetic agents has been shown to be less efficacious and sometimes even harmful in diabetic patients with conco...

    Authors: Jagdeep S. S. Singh, Amir Fathi, Keeran Vickneson, Ify Mordi, Mohapradeep Mohan, J. Graeme Houston, Ewan R. Pearson, Allan D. Struthers and Chim C. Lang
    Citation: Cardiovascular Diabetology 2016 15:97
  20. The effects of insulin on cardiomyocytes, such as positive inotropic action and glucose uptake are well described. However, in vitro studies comparing long-acting insulin analogues with regard to cardiomyocyte...

    Authors: Thorsten Hartmann, Sabrina Overhagen, D. Margriet Ouwens, Silja Raschke, Paulus Wohlfart, Norbert Tennagels, Nina Wronkowitz and Jürgen Eckel
    Citation: Cardiovascular Diabetology 2016 15:96
  21. Vascular stiffening, a risk factor for cardiovascular disease, is accelerated, particularly in women with obesity and type 2 diabetes. Preclinical evidence suggests that dipeptidylpeptidase-4 (DPP-4) inhibitor...

    Authors: Camila Manrique, Javad Habibi, Annayya R. Aroor, James R. Sowers, Guanghong Jia, Melvin R. Hayden, Mona Garro, Luis A. Martinez-Lemus, Francisco I. Ramirez-Perez, Thomas Klein, Gerald A. Meininger and Vincent G. DeMarco
    Citation: Cardiovascular Diabetology 2016 15:94
  22. Obesity is associated with multiple adverse cardiovascular conditions and may increase the risk of ventricular tachyarrhythmias (VT/VF). There is limited data on the association between obesity and risk of VT/...

    Authors: Barbara Szepietowska, Bronislava Polonsky, Saadia Sherazi, Yitschak Biton, Valentina Kutyifa, Scott McNitt, Mehmet Aktas, Arthur J. Moss and Wojciech Zareba
    Citation: Cardiovascular Diabetology 2016 15:93
  23. It is not clear how severe metabolic syndrome (MS) affects the development of coronary atherosclerosis.

    Authors: Lee Kyung Kim, Ji Won Yoon, Dong-Hwa Lee, Kyoung Min Kim, Sung Hee Choi, Kyong Soo Park, Hak Chul Jang, Min-Kyung Kim, Hyo Eun Park, Su-Yeon Choi and Soo Lim
    Citation: Cardiovascular Diabetology 2016 15:92
  24. To evaluate the role of the autonomic nervous system (ANS) in the development of insulin resistance (IR) and assess the relationship between IR and activity of ANS using power spectrum analysis of heart rate v...

    Authors: Maria K. Svensson, Stina Lindmark, Urban Wiklund, Peter Rask, Marcus Karlsson, Jan Myrin, Joel Kullberg, Lars Johansson and Jan W. Eriksson
    Citation: Cardiovascular Diabetology 2016 15:91
  25. Omentin-1, a novel adipocytokine mainly expressed in visceral adipose tissue, has been found to inhibit the inflammatory response and improve insulin resistance as well as other obesity-related disorders. This...

    Authors: Yu Du, Qingwei Ji, Lun Cai, Fangjiong Huang, Yongqiang Lai, Yue Liu, Jianbo Yu, Bo Han, Enjun Zhu, Jinwei Zhang, Yujie Zhou, Zhijian Wang and Yingxin Zhao
    Citation: Cardiovascular Diabetology 2016 15:90
  26. Combination therapy with canagliflozin and insulin was investigated in a prescribed substudy of the canagliflozin Cardiovascular Assessment Study (CANVAS); however, it was not evaluated in Japanese patients wi...

    Authors: Nobuya Inagaki, Shin-ichi Harashima, Nobuko Maruyama, Yutaka Kawaguchi, Maki Goda and Hiroaki Iijima
    Citation: Cardiovascular Diabetology 2016 15:89
  27. Endothelial dysfunction has been suggested as a possible causal link between hyperglycemia and microvascular complications in diabetes mellitus. The effect of metformin on endothelial progenitor cells (EPCs) i...

    Authors: Jia-Wen Yu, Ya-Ping Deng, Xue Han, Guo-Fei Ren, Jian Cai and Guo-Jun Jiang
    Citation: Cardiovascular Diabetology 2016 15:88
  28. Xanthine oxidase inhibitors are anti-hyperuricemic drugs that decrease serum uric acid levels by inhibiting its synthesis. Xanthine oxidase is also recognized as a pivotal enzyme in the production of oxidative...

    Authors: Jun-ichi Oyama, Atsushi Tanaka, Yasunori Sato, Hirofumi Tomiyama, Masataka Sata, Tomoko Ishizu, Isao Taguchi, Takanori Kuroyanagi, Hiroki Teragawa, Nobukazu Ishizaka, Yumiko Kanzaki, Mitsuru Ohishi, Kazuo Eguchi, Yukihito Higashi, Hirotsugu Yamada, Koji Maemura…
    Citation: Cardiovascular Diabetology 2016 15:87
  29. There is an increasing appreciation for a series of less traditional risk factors that should not be ignored when considering type 2 diabetes, obesity, hypertension, and cardiovascular disease. These include a...

    Authors: Craig L. Hanis, Susan Redline, Brian E. Cade, Graeme I. Bell, Nancy J. Cox, Jennifer E. Below, Eric L. Brown and David Aguilar
    Citation: Cardiovascular Diabetology 2016 15:86
  30. To assess the 9-year changes of the incidence and characteristics of metabolic syndrome (MetS) in Chinese community under the background of dramatically changed environment.

    Authors: Boren Jiang, Bin Li, Yongbin Wang, Bing Han, Ningjian Wang, Qin Li, Weihong Yang, Guolan Huang, Jinhua Wang, Yi Chen, Yingchao Chen, Chunfang Zhu, Dongping Lin and Yingli Lu
    Citation: Cardiovascular Diabetology 2016 15:84
  31. In patients with type 2 diabetes, the prognostic impact of an orthostatic rise in blood pressure is not known. Therefore, the aim of this study was to determine the prognostic implications of the diastolic ort...

    Authors: Magnus Wijkman, Toste Länne, Carl Johan Östgren and Fredrik H. Nystrom
    Citation: Cardiovascular Diabetology 2016 15:83
  32. Hyperglycemia is acknowledged as a pro-inflammatory condition and a major cause of vascular damage. Nevertheless, we have previously described that high glucose only promotes inflammation in human vascular cel...

    Authors: Concepción Peiró, Tania Romacho, Verónica Azcutia, Laura Villalobos, Emilio Fernández, Juan P. Bolaños, Salvador Moncada and Carlos F. Sánchez-Ferrer
    Citation: Cardiovascular Diabetology 2016 15:82

    The Erratum to this article has been published in Cardiovascular Diabetology 2017 16:25

  33. The risk for a first myocardial infarction (MI) in people with diabetes has been shown to be as high as the risk for a new MI in non-diabetic patients with a prior MI. Consequently, risk-reducing statin therap...

    Authors: Martin Bødtker Mortensen, Imra Kulenovic and Erling Falk
    Citation: Cardiovascular Diabetology 2016 15:81
  34. We have previously shown that a Palaeolithic diet consisting of the typical food groups that our ancestors ate during the Palaeolithic era, improves cardiovascular disease risk factors and glucose control comp...

    Authors: Maelán Fontes-Villalba, Staffan Lindeberg, Yvonne Granfeldt, Filip K. Knop, Ashfaque A. Memon, Pedro Carrera-Bastos, Óscar Picazo, Madhvi Chanrai, Jan Sunquist, Kristina Sundquist and Tommy Jönsson
    Citation: Cardiovascular Diabetology 2016 15:80
  35. Several studies have revealed that glucose fluctuations provoke oxidative stress that leads to endothelial cell dysfunction, progression of coronary atherosclerosis, and plaque vulnerability. However, little i...

    Authors: Masaru Kuroda, Toshiro Shinke, Hiromasa Otake, Daisuke Sugiyama, Tomofumi Takaya, Hachidai Takahashi, Daisuke Terashita, Kenzo Uzu, Natsuko Tahara, Daiji Kashiwagi, Koji Kuroda, Yuto Shinkura, Yoshinori Nagasawa, Kazuhiko Sakaguchi, Yushi Hirota, Wataru Ogawa…
    Citation: Cardiovascular Diabetology 2016 15:79
  36. To identify possible differences in cardiovascular (CV) risk among different insulin therapies, we performed pre-specified meta-analyses across the clinical program for basal insulin peglispro (BIL), in patien...

    Authors: Byron J. Hoogwerf, A. Michael Lincoff, Angel Rodriguez, Lei Chen and Yongming Qu
    Citation: Cardiovascular Diabetology 2016 15:78
  37. Impaired vasoreactivity is often observed in subjects with metabolic syndrome, a condition that includes the presence of a specific cluster of risk factors for obesity and cardiovascular disease. However, hier...

    Authors: Michio Shimabukuro, Namio Higa, Hiroaki Masuzaki, Masataka Sata and Shinichiro Ueda
    Citation: Cardiovascular Diabetology 2016 15:77
  38. The aim of the present study was to elucidate the effect of teneligliptin on oxidative stress and endothelial function in Japanese patients with type 2 diabetes and chronic kidney disease (CKD).

    Authors: Masaaki Sagara, Kunihiro Suzuki, Chie Aoki, Seiichi Tanaka, Isao Taguchi, Teruo Inoue and Yoshimasa Aso
    Citation: Cardiovascular Diabetology 2016 15:76
  39. Type-2 diabetics have an increased risk of cardiomyopathy, and heart failure is a major cause of death among these patients. Growing evidence indicates that proinflammatory cytokines may induce the development...

    Authors: Sevil Korkmaz-Icöz, Samer Al Said, Tamás Radovits, Shiliang Li, Maik Brune, Péter Hegedűs, Ayhan Atmanli, Mihály Ruppert, Paige Brlecic, Lorenz Heyne Lehmann, Bernd Lahrmann, Niels Grabe, Yutaka Yoshikawa, Hiroyuki Yasui, Patrick Most, Matthias Karck…
    Citation: Cardiovascular Diabetology 2016 15:75
  40. Previous studies have reported an increasing prevalence of metabolic abnormalities in immigrants who moved from low-cardiovascular-risk regions to Western countries, but little is known about time trends follo...

    Authors: Yonatan Reuven, Jacob Dreiher and Pesach Shvartzman
    Citation: Cardiovascular Diabetology 2016 15:74
  41. Low birth weight is associated with increased rates of obesity, insulin resistance and type 2 diabetes, but the precise mechanisms for this association remain unclear. We aimed to assess the relationships betw...

    Authors: François R. Jornayvaz, Peter Vollenweider, Murielle Bochud, Vincent Mooser, Gérard Waeber and Pedro Marques-Vidal
    Citation: Cardiovascular Diabetology 2016 15:73
  42. To analyze whether medical care is in accordance with guidelines for secondary prevention of myocardial infarction (MI), or stroke in patients with type 2 diabetes from Germany and Austria.

    Authors: Barbara Bohn, Christof Schöfl, Vincent Zimmer, Michael Hummel, Nikolai Heise, Erhard Siegel, Wolfram Karges, Michaela Riedl and Reinhard W. Holl
    Citation: Cardiovascular Diabetology 2016 15:72
  43. Intracellular antioxidant response to high glucose is mediated by Cu/Mn-superoxide dismutases (SOD-1/SOD-2), catalase (CAT) and glutathione peroxidases (GPx), particularly glutathione peroxidase-1 (GPx-1). Alt...

    Authors: Lucia La Sala, Monica Cattaneo, Valeria De Nigris, Gemma Pujadas, Roberto Testa, Anna R. Bonfigli, Stefano Genovese and Antonio Ceriello
    Citation: Cardiovascular Diabetology 2016 15:71
  44. Selenoprotein S (SelS) is a transmembrane protein that is expressed in the liver, skeletal muscle, adipose tissue, pancreatic islets, kidney, and blood vessels. In addition to its transmembrane localization, S...

    Authors: Shan-shan Yu, Li–li Men, Jia-ling Wu, Li-wei Huang, Qian Xing, Jun-jie Yao, Yong-bo Wang, Gui-rong Song, Hui-shu Guo, Guo-hua Sun, Yu-hong Zhang, Hua Li and Jian-ling Du
    Citation: Cardiovascular Diabetology 2016 15:70
  45. To evaluate the clinical value of metabolic syndrome based on different definitions [American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI), International Diabetes Federation (IDF) and...

    Authors: Thijs T. W. van Herpt, Abbas Dehghan, Mandy van Hoek, M. Arfan Ikram, Albert Hofman, Eric J. G. Sijbrands and Oscar H. Franco
    Citation: Cardiovascular Diabetology 2016 15:69
  46. Microvascular function is impaired in patients with stable coronary artery disease. The aim was to study microvascular function in patients with diabetes and acute coronary syndrome (ACS).

    Authors: Nikolaos Östlund Papadogeorgos, Gun Jörneskog, Mattias Bengtsson, Thomas Kahan and Majid Kalani
    Citation: Cardiovascular Diabetology 2016 15:66
  47. Previous evidences have shown the presence of a prolonged and exaggerated postprandial response in type 2 diabetes mellitus (T2DM) and its relation with an increase of cardiovascular risk. However, the respons...

    Authors: A. Leon-Acuña, J. F. Alcala-Diaz, J. Delgado-Lista, J. D. Torres-Peña, J. Lopez-Moreno, A. Camargo, A. Garcia-Rios, C. Marin, F. Gomez-Delgado, J. Caballero, B. Van-Ommen, M. M. Malagon, P. Perez-Martinez and J. Lopez-Miranda
    Citation: Cardiovascular Diabetology 2016 15:68
  48. Low-grade systemic inflammation is considered to participate in the progression of type 2 diabetes (T2D) and in diabetic complications.

    Authors: Bernt Johan von Scholten, Alexander Rosendahl, Philip Hasbak, Regine Bergholdt, Andreas Kjaer, Peter Rossing and Tine W. Hansen
    Citation: Cardiovascular Diabetology 2016 15:67

Cardiovascular Diabetology is affiliated with Sackler Faculty of Medicine, Tel-Aviv University

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