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  1. Serum haptoglobin (Hp) has been closely associated with cardio-cerebrovascular diseases. We investigated a metabolic profile associated with circulating Hp and carotid arterial functions via a targeted metabol...

    Authors: Shiyun Wang, Jie Wang, Rong Zhang, Aihua Zhao, Xiaojiao Zheng, Dandan Yan, Feng Jiang, Wei Jia, Cheng Hu and Weiping Jia
    Citation: Cardiovascular Diabetology 2019 18:8
    Content type: Original investigation Published on:

  2. Metabolic abnormalities have been implicated as a causal event in diabetic cardiomyopathy (DCM). However, the mechanisms underlying cardiac metabolic disorder in DCM were not fully understood.

    Authors: Zhongwei Yin, Yanru Zhao, Mengying He, Huaping Li, Jiahui Fan, Xiang Nie, Mengwen Yan, Chen Chen and Dao Wen Wang
    Citation: Cardiovascular Diabetology 2019 18:7
    Content type: Original investigation Published on:

  4. Diabetes mellitus (DM) is a prevalent metabolic disease characterized by chronic hyperglycemia. A primary burden of DM is related to its long-term complications, which have been shown to impact the course of h...

    Authors: Kassem Sharif, Suheil Ghadir, Daniela Jakubowicz, Howard Amital, Nicola Luigi Bragazzi, Abdulla Watad, Julio Wainstein and Yosefa Bar-Dayan
    Citation: Cardiovascular Diabetology 2019 18:4
    Content type: Original investigation Published on:

  5. Epicardial fat tissue (EFT) is the visceral fat distributed along the coronary arteries between the pericardium and the myocardium. Increases in EFT are closely related to the occurrence of diabetes mellitus (...

    Authors: Yingrui Li, Bin Liu, Yu Li, Xiaodong Jing, Songbai Deng, Yulin Yan and Qiang She
    Citation: Cardiovascular Diabetology 2019 18:3
    Content type: Original investigation Published on:

  6. The prognostic importance of carotid atherosclerosis in individuals with diabetes is unsettled. We aimed to evaluate the relationships between parameters of carotid atherosclerosis and the future occurrence of...

    Authors: Claudia R. L. Cardoso, Guilherme C. Salles, Nathalie C. Leite and Gil F. Salles
    Citation: Cardiovascular Diabetology 2019 18:2
    Content type: Original investigation Published on:

  7. In heart failure the myocardium becomes insulin resistant which negatively influences cardiac energy metabolism and function, while increasing cardiac insulin signalling improves cardiac function and prevents ...

    Authors: Qutuba G. Karwi, Liyan Zhang, Cory S. Wagg, Wang Wang, Manoj Ghandi, Dung Thai, Hai Yan, John R. Ussher, Gavin Y. Oudit and Gary D. Lopaschuk
    Citation: Cardiovascular Diabetology 2019 18:1
    Content type: Original investigation Published on:

  8. Several studies have shown that bariatric surgery reduces long term mortality compared to medical weight loss therapy. In a previous study we have demonstrated that gastric banding (LAGB) is associated with re...

    Authors: Antonio E. Pontiroli, Ahmed S. Zakaria, Marco Fanchini, Chiara Osio, Elena Tagliabue, Giancarlo Micheletto, Alessandro Saibene and Franco Folli
    Citation: Cardiovascular Diabetology 2018 17:161
    Content type: Original investigation Published on:

  9. There are increasing evidence that left ventricle diastolic dysfunction is the initial functional alteration in the diabetic myocardium. In this study, we hypothesized that alogliptin prevents diastolic dysfun...

    Authors: Xiaowei Zhang, Zhiwei Zhang, Yajuan Yang, Ya Suo, Ruimeng Liu, Jiuchun Qiu, Yungang Zhao, Ning Jiang, Changle Liu, Gary Tse, Guangping Li and Tong Liu
    Citation: Cardiovascular Diabetology 2018 17:160
    Content type: Original investigation Published on:

  10. Following publication of the original article [1], the authors reported an error in Acknowledgment section. The last sentence should read as “All authors have read and approval the submission to Cardiovascular...

    Authors: Celestino Sardu, Michelangela Barbieri, Maria Luisa Balestrieri, Mario Siniscalchi, Pasquale Paolisso, Paolo Calabrò, Fabio Minicucci, Giuseppe Signoriello, Michele Portoghese, Pasquale Mone, Davide D’Andrea, Felice Gragnano, Alessandro Bellis, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo…
    Citation: Cardiovascular Diabetology 2018 17:159
    Content type: Correction Published on:

    The original article was published in Cardiovascular Diabetology 2018 17:152

  11. Patients with type 1 diabetes (T1DM) have increased mortality from cardiovascular disease (CVD). Risk factors for CVD include an elevation of LDL (LDLp) and small HDL (sHDLp) particles, and a decrease in rever...

    Authors: Evgenia Gourgari, Martin P. Playford, Umberto Campia, Amit K. Dey, Fran Cogen, Stephanie Gubb-Weiser, Mihriye Mete, Sameer Desale, Maureen Sampson, Allen Taylor, Kristina I. Rother, Alan T. Remaley and Nehal N. Mehta
    Citation: Cardiovascular Diabetology 2018 17:158
    Content type: Original investigation Published on:

  12. Patients with type 2 diabetes (T2DM) have a substantial risk of developing cardiovascular disease. The strong connection between the severity of hyperglycaemia, metabolic changes secondary to T2DM and vascular...

    Authors: Andrei C. Sposito, Otávio Berwanger, Luiz Sérgio F. de Carvalho and José Francisco Kerr Saraiva
    Citation: Cardiovascular Diabetology 2018 17:157
    Content type: Review Published on:

    The Correction to this article has been published in Cardiovascular Diabetology 2019 18:23

  13. The pathophysiology of cardiovascular complications in people with type 1 diabetes (T1DM) remains unclear. An increase in epicardial adipose tissue (EAT) and alterations in the composition of high-density lipo...

    Authors: Cristina Colom, David Viladés, Montserrat Pérez-Cuellar, Rubén Leta, Andrea Rivas-Urbina, Gemma Carreras, Jordi Ordóñez-Llanos, Antonio Pérez and Jose Luis Sánchez-Quesada
    Citation: Cardiovascular Diabetology 2018 17:156
    Content type: Original investigation Published on:

  14. Increasing evidence suggest that statin therapy has a diabetogenic effect. Individual types of statin may have a different effect on glucose metabolism. Using the repeated nationwide population-based health sc...

    Authors: Jinkwon Kim, Hye Sun Lee and Kyung-Yul Lee
    Citation: Cardiovascular Diabetology 2018 17:155
    Content type: Original investigation Published on:

  15. Epidemiological studies have demonstrated a relationship between cognitive function in youth and the future risk of death. Less is known regarding the relationship with diabetes related death. This study asses...

    Authors: Gilad Twig, Amir Tirosh, Estela Derazne, Ziona Haklai, Nehama Goldberger, Arnon Afek, Hertzel C. Gerstein, Jeremy D. Kark and Tali Cukierman-Yaffe
    Citation: Cardiovascular Diabetology 2018 17:154
    Content type: Original investigation Published on:

  16. Deteriorated arterial function and high incidence of cardiovascular events characterise diabetes mellitus. Metformin and recent antidiabetic drugs, SGLT2 inhibitors, reduce cardiovascular events. We explored t...

    Authors: Mojca Lunder, Miodrag Janić, Miha Japelj, Andrej Juretič, Andrej Janež and Mišo Šabovič
    Citation: Cardiovascular Diabetology 2018 17:153
    Content type: Original investigation Published on:

  17. We evaluate whether the thrombus aspiration (TA) before primary percutaneous coronary intervention (PPCI) may improve STEMI outcomes in hyperglycemic patients.

    Authors: Celestino Sardu, Michelangela Barbieri, Maria Luisa Balestrieri, Mario Siniscalchi, Pasquale Paolisso, Paolo Calabrò, Fabio Minicucci, Giuseppe Signoriello, Michele Portoghese, Pasquale Mone, Davide D’Andrea, Felice Gragnano, Alessandro Bellis, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo…
    Citation: Cardiovascular Diabetology 2018 17:152
    Content type: Original investigation Published on:

    The Correction to this article has been published in Cardiovascular Diabetology 2018 17:159

  18. Type 2 diabetes mellitus (DM) is a frequent co-morbidity among patients undergoing coronary artery bypass grafting (CABG) surgery. The aim of this study was to evaluate the impact of DM on the early- and long-...

    Authors: Alexander Kogan, Eilon Ram, Shany Levin, Enrique Z. Fisman, Alexander Tenenbaum, Ehud Raanani and Leonid Sternik
    Citation: Cardiovascular Diabetology 2018 17:151
    Content type: Original investigation Published on:

  19. The global prevalence of type 2 diabetes-related complications is not well described. We assessed prevalence of vascular complications at baseline in DISCOVER (NCT02322762; NCT02226822), a global, prospective,...

    Authors: Mikhail Kosiborod, Marilia B. Gomes, Antonio Nicolucci, Stuart Pocock, Wolfgang Rathmann, Marina V. Shestakova, Hirotaka Watada, Iichiro Shimomura, Hungta Chen, Javier Cid-Ruzafa, Peter Fenici, Niklas Hammar, Filip Surmont, Fengming Tang and Kamlesh Khunti
    Citation: Cardiovascular Diabetology 2018 17:150
    Content type: Original investigation Published on:

  20. Negative coronary artery remodeling is frequent in patients with diabetes, but its mechanism remains unclear. We here evaluated the association of serum levels of glycated albumin (GA) and endogenous secretory...

    Authors: Run Du, Rui Yan Zhang, Lin Lu, Ying Shen, Li Jin Pu, Zheng Bin Zhu, Qi Zhang, Jian Hu, Zhen Kun Yang, Feng Hua Ding, Jian Sheng Zhang and Wei Feng Shen
    Citation: Cardiovascular Diabetology 2018 17:149
    Content type: Original investigation Published on:

  22. Guidelines have classified patients with acute coronary syndrome (ACS) and diabetes as a special population, with specific sections presented for the management of these patients considering their extremely hi...

    Authors: Mengge Zhou, Jing Liu, Yongchen Hao, Jun Liu, Yong Huo, Sidney C. Smith Jr., Junbo Ge, Changsheng Ma, Yaling Han, Gregg C. Fonarow, Kathryn A. Taubert, Louise Morgan, Na Yang, Yueyan Xing and Dong Zhao
    Citation: Cardiovascular Diabetology 2018 17:147
    Content type: Original investigation Published on:

  23. Little is known about factors that affect the composition of contracted blood clots in specific diseases. We investigated the content of polyhedral erythrocytes (polyhedrocytes) formed in blood clots and its d...

    Authors: Grzegorz Gajos, Aleksander Siniarski, Joanna Natorska, Michał Ząbczyk, Jakub Siudut, Krzysztof Piotr Malinowski, Renata Gołębiowska-Wiatrak, Paweł Rostoff and Anetta Undas
    Citation: Cardiovascular Diabetology 2018 17:146
    Content type: Original investigation Published on:

  24. Cardiovascular disease (CVD) is the most significant prognostic factor in individuals with type 2 diabetes (T2D). However, a significant number of individuals may develop CVD that does not present with the cla...

    Authors: Guntram Schernthaner, Chaim Lotan, Elina Baltadzhieva-Trendafilova, Jonas Ceponis, Martin Clodi, Kristine Ducena, Eva Goncalvesova, Cristian Guja, Marek Honka, Andrej Janež, Nebojša Lalić, Roger Lehmann, Noémi Nyolczas, Priit Pauklin, Andrzej Rynkiewicz, Igor Sergienko…
    Citation: Cardiovascular Diabetology 2018 17:145
    Content type: Commentary Published on:

  25. Metabolic syndrome (MetS) is a prevalent risk factor for cardiac dysfunction. Although SGLT2-inhibitors have important cardioprotective effects in hyperglycemia, their underlying mechanisms are complex and not...

    Authors: Aysegul Durak, Yusuf Olgar, Sinan Degirmenci, Erman Akkus, Erkan Tuncay and Belma Turan
    Citation: Cardiovascular Diabetology 2018 17:144
    Content type: Original investigation Published on:

  26. The aim of this study was to investigate the interrelationships between three bone-derived factors [serum osteocalcin (OCN), fibroblast growth factor (FGF) 23, and neutrophil gelatinase-associated lipocalin (N...

    Authors: Yiting Xu, Xiaojing Ma, Xiaoping Pan, Xingxing He, Yunfeng Xiao and Yuqian Bao
    Citation: Cardiovascular Diabetology 2018 17:143
    Content type: Original investigation Published on:

  27. It is well known that angiopoietin-like protein 8 (ANGPTL8) exerts its effects on lipid metabolism through the inhibition of lipoprotein lipase and subsequent elevation of plasma triglyceride. However, it is n...

    Authors: Mengdie Luo, Ziyu Zhang, Yani Peng, Shuai Wang and Daoquan Peng
    Citation: Cardiovascular Diabetology 2018 17:142
    Content type: Original investigation Published on:

  28. A strong correlation exists between type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), with CVD and the presence of atherosclerosis being the prevailing cause of morbidity and mortality in diabe...

    Authors: Lesha Pretorius, Greig J. A. Thomson, Rozanne C. M. Adams, Theo A. Nell, Willem A. Laubscher and Etheresia Pretorius
    Citation: Cardiovascular Diabetology 2018 17:141
    Content type: Original investigation Published on:

  29. The aim of the study was to investigate whether intravenous (iv) infusion of exenatide, a synthetic GLP-1 receptor agonist, could provide a protective effect against myocardial ischemia-reperfusion injury afte...

    Authors: Guillaume Besch, Andrea Perrotti, Lucie Salomon du Mont, Marc Puyraveau, Xavier Ben-Said, Maude Baltres, Benoit Barrucand, Guillaume Flicoteaux, Lucie Vettoretti, Emmanuel Samain, Sidney Chocron and Sebastien Pili-Floury
    Citation: Cardiovascular Diabetology 2018 17:140
    Content type: Original investigation Published on:

  30. Early detection of subclinical myocardial dysfunction in patients with diabetes mellitus (DM) is essential for recommending therapeutic interventions that can prevent or reverse heart failure, thereby improvin...

    Authors: Xi Liu, Zhi-gang Yang, Yue Gao, Lin-jun Xie, Li Jiang, Bi-yue Hu, Kai-yue Diao, Ke Shi, Hua-yan Xu, Meng-ting Shen, Yan Ren and Ying-kun Guo
    Citation: Cardiovascular Diabetology 2018 17:139
    Content type: Original investigation Published on:

  31. Lower-extremity arterial disease (LEAD) is a major endemic disease with an alarming increased prevalence worldwide. It is a common and severe condition with excess risk of major cardiovascular events and death...

    Authors: Mathilde Nativel, Louis Potier, Laure Alexandre, Laurence Baillet-Blanco, Eric Ducasse, Gilberto Velho, Michel Marre, Ronan Roussel, Vincent Rigalleau and Kamel Mohammedi
    Citation: Cardiovascular Diabetology 2018 17:138
    Content type: Review Published on:

  32. To evaluate clinical outcomes in patients with diabetes, treated by cardiac resynchronization therapy with a defibrillator (CRT-d), and glucagon-like peptide 1 receptor agonists (GLP-1 RA) in addition to conve...

    Authors: Celestino Sardu, Pasquale Paolisso, Cosimo Sacra, Matteo Santamaria, Claudio de Lucia, Antonio Ruocco, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo, Michelangela Barbieri and Raffaele Marfella
    Citation: Cardiovascular Diabetology 2018 17:137
    Content type: Original investigation Published on:

  33. Little is known about the association of hyperglycemia with the development of ventricular tachycardia (VT) in patients hospitalized with acute myocardial infarction (AMI) which we examined in the present stud...

    Authors: Hoang V. Tran, Joel M. Gore, Chad E. Darling, Arlene S. Ash, Catarina I. Kiefe and Robert J. Goldberg
    Citation: Cardiovascular Diabetology 2018 17:136
    Content type: Original investigation Published on:

  34. The aims of this study were to examine trends in the incidence and in-hospital outcomes of SAVR among T2DM patients from 2001 to 2015, to compare clinical variables among T2DM patients and matched non-T2DM pat...

    Authors: Ana López-de-Andrés, Napoleon Perez-Farinos, Javier de Miguel-Díez, Valentín Hernández-Barrera, Manuel Méndez-Bailón, José M. de Miguel-Yanes and Rodrigo Jiménez-García
    Citation: Cardiovascular Diabetology 2018 17:135
    Content type: Original investigation Published on:

  35. Perivascular adipose tissue (PVAT), the adipose tissue that surrounds most of the vasculature, has emerged as an active component of the blood vessel wall regulating vascular homeostasis and affecting the path...

    Authors: Xiao-Yan Qi, Shun-Lin Qu, Wen-Hao Xiong, Oren Rom, Lin Chang and Zhi-Sheng Jiang
    Citation: Cardiovascular Diabetology 2018 17:134
    Content type: Review Published on:

  36. Gestational diabetes (GDM) and milder gestational impaired glucose tolerance (GIGT) identify women at risk of developing type 2 diabetes and cardiovascular disease later in life. Accordingly, the postpartum ye...

    Authors: Sadia Mehmood, Chang Ye, Philip W. Connelly, Anthony J. Hanley, Bernard Zinman and Ravi Retnakaran
    Citation: Cardiovascular Diabetology 2018 17:133
    Content type: Original investigation Published on:

  37. The objective of this study was to investigate the impact of sodium glucose cotransporter type 2 (SGLT2) inhibitors on left ventricular (LV) diastolic function of type 2 diabetes mellitus (T2DM) patients with ...

    Authors: Fumitaka Soga, Hidekazu Tanaka, Kazuhiro Tatsumi, Yasuhide Mochizuki, Hiroyuki Sano, Hiromi Toki, Kensuke Matsumoto, Junya Shite, Hideyuki Takaoka, Tomofumi Doi and Ken-ichi Hirata
    Citation: Cardiovascular Diabetology 2018 17:132
    Content type: Original investigation Published on:

  38. As a strong platelet agonist on the one hand and key molecule in plasmatic coagulation on the other hand, thrombin connects primary and secondary hemostasis. Thrombin generation potential reflects the individu...

    Authors: Silvia Lee, Cihan Ay, Christoph W. Kopp, Simon Panzer and Thomas Gremmel
    Citation: Cardiovascular Diabetology 2018 17:131
    Content type: Original investigation Published on:

  39. Diabetes mellitus (DM) correlates with accelerated aging and earlier appearance of geriatric phenotypes, including frailty. However, whether pre-frailty or frailty predicts greater healthcare utilization in di...

    Authors: Chia-Ter Chao, Jui Wang and Kuo-Liong Chien
    Citation: Cardiovascular Diabetology 2018 17:130
    Content type: Original investigation Published on:

  40. We used a network meta-analysis of randomized controlled trials (RCTs) to comparatively examine the effects of oral antidiabetic drugs (OADs) on left ventricular mass (LVM) in patients with type 2 diabetes.

    Authors: Satoshi Ida, Ryutaro Kaneko and Kazuya Murata
    Citation: Cardiovascular Diabetology 2018 17:129
    Content type: Original investigation Published on:

  41. Diabetes converts from a metabolic disorder into a predominantly vascular disease, once its duration extends over several years or/and when additional cardiovascular risk factors such as hypertension coexist. ...

    Authors: Dennis Kannenkeril, Agnes Bosch, Joanna Harazny, Marina Karg, Susanne Jung, Christian Ott and Roland E. Schmieder
    Citation: Cardiovascular Diabetology 2018 17:128
    Content type: Original investigation Published on:

  42. Type 2 diabetes mellitus (T2D), rapidly increasing to epidemic proportions, globally escalates cardiovascular disease risk. Although intensive interventions and comprehensive management of environmental risks ...

    Authors: Cheng Liu, Yanfang Li, Tianwang Guan, Yanxian Lai, Yan Shen, Abudurexiti Zeyaweiding, Haiyan Zhao, Fang Li and Tutiguli Maimaiti
    Citation: Cardiovascular Diabetology 2018 17:127
    Content type: Original investigation Published on:

  43. Ambiguity exists in relation to the role of physical activity (PA) for cardiovascular disease (CVD) risk reduction. We examined the interplay between PA dimensions and more conventional CVD risk factors to ass...

    Authors: Hanan Amadid, Nanna B. Johansen, Anne-Louise Bjerregaard, Søren Brage, Kristine Færch, Torsten Lauritzen, Daniel R. Witte, Annelli Sandbæk, Marit E. Jørgensen and Dorte Vistisen
    Citation: Cardiovascular Diabetology 2018 17:126
    Content type: Original investigation Published on:

  44. The study sought to assess the prognostic impact of type 2 diabetes in patients presenting with ventricular tachyarrhythmias on admission.

    Authors: Kathrin Weidner, Michael Behnes, Tobias Schupp, Jonas Rusnak, Linda Reiser, Armin Bollow, Gabriel Taton, Thomas Reichelt, Dominik Ellguth, Niko Engelke, Jorge Hoppner, Ibrahim El-Battrawy, Kambis Mashayekhi, Christel Weiß, Martin Borggrefe and Ibrahim Akin
    Citation: Cardiovascular Diabetology 2018 17:125
    Content type: Original investigation Published on:

  45. Women with history of hypertensive disorders of pregnancy (HDP) are at increased risk of early onset cardiovascular disease and type 2 diabetes (T2D). We aimed to investigate the extent to which HDP is also as...

    Authors: Simon Timpka, Amanda Markovitz, Tommy Schyman, Ingrid Mogren, Abigail Fraser, Paul W. Franks and Janet W. Rich-Edwards
    Citation: Cardiovascular Diabetology 2018 17:124
    Content type: Original investigation Published on:

  46. Diabetes is a leading cause of mortality and morbidity across the world. Over 50% of deaths among diabetic patients are caused by cardiovascular diseases. Cardiac diastolic dysfunction is one of the key early ...

    Authors: Beibei Dai, Huaping Li, Jiahui Fan, Yanru Zhao, Zhongwei Yin, Xiang Nie, Dao Wen Wang and Chen Chen
    Citation: Cardiovascular Diabetology 2018 17:123
    Content type: Original investigation Published on:

  47. For many years, cardiovascular disease (CVD) has been the leading cause of death around the world. Often associated with CVD are comorbidities such as obesity, abnormal lipid profiles and insulin resistance. I...

    Authors: Valeska Ormazabal, Soumyalekshmi Nair, Omar Elfeky, Claudio Aguayo, Carlos Salomon and Felipe A. Zuñiga
    Citation: Cardiovascular Diabetology 2018 17:122
    Content type: Review Published on:

  48. The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes, accounting for approximately 90–95...

    Authors: Raminderjit Kaur, Manpreet Kaur and Jatinder Singh
    Citation: Cardiovascular Diabetology 2018 17:121
    Content type: Review Published on:

  49. The N-terminal prohormone of brain natriuretic peptide (NT-proBNP) is an important biomarker for the diagnosis of heart failure. Apart from this and only recently recognized, NT-proBNP levels associate with hi...

    Authors: Annette Masuch, Maik Pietzner, Martin Bahls, Kathrin Budde, Gabi Kastenmüller, Stephanie Zylla, Anna Artati, Jerzy Adamski, Henry Völzke, Marcus Dörr, Stephan B. Felix, Matthias Nauck and Nele Friedrich
    Citation: Cardiovascular Diabetology 2018 17:120
    Content type: Original investigation Published on:

  50. There is a vast disagreement in relation to the possible beneficial effects of omega-3 polyunsaturated fatty acids (omega-3 PUFA) supplementation in patients with diabetes and cardiovascular disease. The confl...

    Authors: Alexander Tenenbaum and Enrique Z. Fisman
    Citation: Cardiovascular Diabetology 2018 17:119
    Content type: Commentary Published on:
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