Fig. 3
The correlation analysis. A–D The change in the calcified plaque volume inversely correlated with achieved LDL-C level (r =  − 0.31, p < 0.001); There was a positive correlation between the change in noncalcified plaque volume and achieved LDL-C level (r = 0.65, p < 0.001); Similar finding were observed in the relationship between necrotic volume and achieved LDL-C level (r = 0.44, p < 0.001). However, the change of PCATRCA density did not correlated with achieved LDL-C level (r =  − 0.12, p = 0.11). E–H There was a negative association between the change of calcified plaque volume and achieved Lp(a) level (r =  − 0.33, p < 0.001); The change in the noncalcified plaque volume positively associated with achieved Lp(a) level (r = 0.68, p < 0.001); Similar finding were observed in the relationship between necrotic volume and achieved LDL-C level (r = 0.39, p < 0.001). In addition, the change in PCATRCA density positively correlated with achieved Lp(a) level (r = 0.51, p < 0.001). CCTA, coronary computed tomography angiography; Lp(a), lipoprotein(a); LDL-C, Low-density lipoprotein cholesterol; PCAT, pericoronary adipose tissue; RCA, right coronary artery