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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Cardiovascular complications of diabetes: role of non-coding RNAs in the crosstalk between immune and cardiovascular systems

Fig. 3

Macrophage ncRNAs in diabetes complications. (a) lncRNA Dnm3os, (b) miR-146a (green square) and miR155 (blue square) deregulations affect inflammatory signaling pathways, accelerating diabetic nephropathy or exacerbating atherosclerosis. DAMPs: damage-associated molecular patterns, IL-1β: interleukin-1 beta, IL-18: interleukin 18, GSDMD: gasdermin D, N-GSDMD: amino-terminal fragments of GSDMD, MAPKs: mitogen-activated protein kinase, NLRP3: NLR family pyrin domain containing 3, NF-κB: nuclear factor kappaB, Ox-LDL: oxidized low-density lipoprotein, AS: atherosclerosis, LV: lentiviral, Dnm3os: dynamin 3 opposite strand. Figure created with BioRender.com online tool

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Cardiovascular Diabetology

ISSN: 1475-2840