Fig. 2From: Cardiovascular complications of diabetes: role of non-coding RNAs in the crosstalk between immune and cardiovascular systemsncRNAs in the dysregulation of the innate immune system in diabetic cardiovascular complications. Examples of ncRNA-dependent deregulation in (a, b) neutrophils, and (c) monocytes in the context of DM cardiovascular complications. (a) miR-146 KO increases NET formation in a mouse model of atherosclerosis; (b) miR-129 in neutrophils mediates apoptosis and inflammation impairment in a diabetic mouse model; (c) Hyperglycemia leads to chronic inflammation through ncRNAs deregulation. NET: neutrophil extracellular trap, Casp6: caspase-6, CCR2: C-C chemokine receptor type 2, DRAIR: diabetes regulated anti-inflammatory RNA, Dnm3os: dynamin 3 opposite strand, EC: endothelial cell. Figure created with BioRender.com online toolBack to article page