Long- and very long-chain ceramides are predictors of acute kidney injury in patients with acute coronary syndrome: the PEACP study

Table 3 Predictive value of ceramides and Mehran risk score for acute kidney injury

Predictors	AUC	95%CI	P for AUC	P for AUC comparison
Mehran risk score	0.780	0.738–0.821	< 0.001	Reference
Cer(d18:1–16:0)	0.619	0.564–0.673	< 0.001	< 0.001
Cer(d18:1–18:0)	0.641	0.589–0.693	< 0.001	< 0.001
Cer(d18:1–20:0)	0.581	0.525–0.637	0.003	< 0.001
Cer(d18:1–21:0)	0.609	0.555–0.662	< 0.001	< 0.001
Cer(d18:1–24:1)	0.618	0.564–0.671	< 0.001	< 0.001
Cer(d18:1–24:2)	0.661	0.614–0.708	< 0.001	< 0.001
Cer(d18:1–16:0) plus MRS	0.807	0.768–0.845	< 0.001	0.021
Cer(d18:1–18:0) plus MRS	0.808	0.770–0.847	< 0.001	0.006
Cer(d18:1–20:0) plus MRS	0.805	0.766–0.843	< 0.001	0.038
Cer(d18:1–21:0) plus MRS	0.802	0.764–0.840	< 0.001	0.031
Cer(d18:1–24:1) plus MRS	0.805	0.766–0.844	< 0.001	0.025
Cer(d18:1–24:2) plus MRS	0.805	0.768–0.843	< 0.001	0.009

The areas under the curves (AUCs) were analyzed by receiver operating characteristic curves. The model of ceramides combined with Mehran risk score was calculated by logistic regression
MRS Mehran risk score, CI confidence interval

ISSN: 1475-2840