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Table 1 Baseline clinical, angiographic, and procedural characteristics and in-hospital outcome of all patients with and without diabetes before and after stratification according to hs-CRP

From: Predictive value of high sensitivity C-reactive protein in three-vessel disease patients with and without type 2 diabetes

Variables

Total population

Patients with diabetes

Patients without diabetes

Diabetes

Non-diabetes

P

Hs-CRP < 2 mg/L

Hs-CRP ≥ 2 mg/L

P

Hs-CRP < 2 mg/L

Hs-CRP ≥ 2 mg/L

P

(n = 1040)

(n = 1694)

(n = 564)

(n = 476)

(n = 812)

(n = 882)

Age, years

65.3 ± 7.9

64.0 ± 10.4

0.001

65.3 ± 9.4

65.3 ± 10.0

0.769

63.6 ± 10.0

64.4 ± 10.7

0.052

Male

719 (69.1)

1328 (78.4)

 < 0.001

401 (71.1)

318 (66.8)

0.135

643 (79.2)

687 (77.7)

0.447

Smoking

381 (36.6)

771 (45.5)

 < 0.001

189 (33.5)

192 (40.3)

0.023

336 (41.4)

435 (49.3)

0.001

Hypertension

776 (74.6)

1062 (62.7)

 < 0.001

425 (75.4)

351 (73.7)

0.551

478 (58.9)

584 (66.6)

0.002

Dyslipidemia

850 (81.7)

1318 (77.8)

0.014

456 (80.9)

394 (82.8)

0.191

617 (76.0)

701 (79.5)

0.084

CKD

116 (11.2)

144 (8.5)

0.022

42 (7.4)

74 (15.5)

 < 0.001

46 (5.7)

98 (11.1)

 < 0.001

Prior MI

50 (4.8)

55 (3.2)

0.039

16 (2.8)

34 (7.1)

0.001

28 (3.4)

27 (3.1)

0.653

Prior PAD

40 (3.8)

46 (2.7)

0.100

19 (3.4)

21 (4.4)

0.384

18 (2.2)

28 (3.2)

0.226

Prior cerebrovascular disease

157 (14.1)

199 (11.7)

0.012

66 (11.7)

80 (16.8)

0.018

93 (11.5)

84 (9.5)

0.195

SBP, mm Hg

139 ± 22

137 ± 23

0.006

139 ± 21

139 ± 23

0.943

138 ± 21

137 ± 24

0.369

DBP, mm Hg

80 ± 23

81 ± 13

0.005

79 ± 10

80 ± 32

0.707

81 ± 13

80 ± 14

0.282

Hs-CRP, mg/L

2.1 (0.7–5.9)

1.8 (0.8–5.6)

0.116

0.8 (0.5–1.4)

2.3 (0.8–5.9)

 < 0.001

0.8 (0.5–1.2)

1.9 (0.7–5.1)

 < 0.001

WBC, 109/L

7.78 ± 2.83

7.71 ± 2.57

0.849

7.41 ± 2.73

8.21 ± 2.90

 < 0.001

7.33 ± 2.42

8.06 ± 2.66

 < 0.001

FBG, mmol/L

10.3 ± 5.0

6.0 ± 2.0

 < 0.001

9.5 ± 4.8

11.3 ± 5.1

 < 0.001

5.8 ± 1.7

6.3 ± 2.3

 < 0.001

HbA1c, %

8.5 ± 1.7

6.2 ± 1.2

0.007

8.3 ± 1.6

8.6 ± 1.8

0.042

6.2 ± 1.3

6.2 ± 1.2

0.315

TC, mmol/L

4.86 ± 1.18

5.04 ± 1.25

0.031

4.81 ± 1.13

4.94 ± 1.25

0.392

4.84 ± 1.22

5.27 ± 1.25

 < 0.001

Triglyceride, mmol/L

2.13 ± 1.51

1.76 ± 1.15

 < 0.001

2.05 ± 1.18

2.26 ± 1.92

0.773

1.62 ± 1.04

1.93 ± 1.25

 < 0.001

HDL-C, mmol/L

1.23 ± 0.31

1.24 ± 0.31

0.787

1.21 ± 0.30

1.26 ± 0.33

0.132

1.21 ± 0.30

1.27 ± 0.31

0.017

LDL-C, mmol/L

2.85 ± 0.79

3.00 ± 0.89

0.011

2.82 ± 0.74

2.89 ± 0.87

0.716

2.87 ± 0.88

3.15 ± 0.88

 < 0.001

Creatinine clearance, mL/min

94 ± 29

89 ± 23

 < 0.001

96 ± 27

91 ± 30

0.021

91 ± 21

88 ± 25

0.032

LVEF, %

52.7 ± 9.2

54.2 ± 7.9

 < 0.001

53.4 ± 8.8

51.8 ± 9.6

 < 0.001

55.0 ± 7.2

53.4 ± 8.5

 < 0.001

Acute coronary syndrome

364 (35.0)

604 (35.7)

0.728

182 (32.3)

182 (38.2)

0.044

247 (30.4)

357 (40.5)

 < 0.001

Revascularization in hospital

937 (90.1)

1559 (92.0)

0.082

509 (90.2)

428 (89.9)

0.858

755 (93.0)

804 (91.1)

0.166

LMT involvement

159 (15.3)

218 (12.9)

0.075

98 (17.4)

61 (12.8)

0.042

105 (12.9)

113 (12.8)

0.942

SYNTAX score

26.1 ± 9.8

24.7 ± 9.6

0.013

25.9 ± 9.9

26.2 ± 10.1

0.614

24.5 ± 9.8

24.9 ± 9.9

0.257

DES used

821 (78.9)

1423 (84.0)

0.001

450 (79.8)

371 (77.9)

0.467

702 (86.5)

721 (81.7)

0.008

In-hospital death

14 (1.3)

5 (0.3)

0.001

5 (0.9)

9 (1.9)

0.161

2 (0.2)

3 (0.3)

0.722

  1. CKD chronic kidney disease, DBP diastolic blood pressure, DES drug-eluting stent, FBG fasting blood glucose, HbA1c glycated hemoglobin, HDL-C high-density lipoprotein cholesterol, Hs-CRP high-sensitivity C-reactive protein, LDL-C low-density lipoprotein cholesterol, LMT left main trunk, LVEF left ventricular ejection fraction, MI myocardial infarction, PAD peripheral artery disease, SBP systolic blood pressure, SYNTAX Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery, TC total cholesterol, WBC white blood cell