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Table 1 Characteristics According to Hypersensitive C-reactive Protein and Low-density Lipoprotein Cholesterol Levels

From: Effect of dual residual risk of cholesterol and inflammation on all-cause mortality in patients with cardiovascular disease

Variables

No residual risk

RIR

RCR

RCIR

p value

Participants, n

613

295

1628

973

 

Age, years

63.23 ± 8.46

63.10 ± 8.40

63.79 ± 8.39

64.00 ± 8.41

0.18

Men, n (%)

552 (90.0)

271 (91.9)

1399 (85.9)

823 (84.6)

< 0.01

BMI, kg/m2

25.75 ± 3.20

26.10 ± 3.43

25.77 ± 3.12

26.42 ± 3.29

< 0.01

TG, mmol/L

1.13 (0.85–1.61)

1.21 (0.84–1.85)

1.28 (0.95–1.82)

1.45 (1.06–2.09)

< 0.01

LDL-C, mmol/L

1.46 (1.19–1.64)

1.45 (1.17–1.63)

2.58 (2.16–3.19)

2.72 (2.25–3.22)

< 0.01

HDL-C, mmol/L

1.15 (0.99–1.42)

1.17 (0.98–1.45)

1.30 (1.11–1.55)

1.23 (1.05–1.46)

< 0.01

SBP, mmHg

139.23 ± 19.66

140.26 ± 19.98

141.49 ± 20.37

144.21 ± 20.63

< 0.01

FBG, mmol/L

5.79 (5.12–6.77)

5.69 (5.04–6.64)

5.70 (5.11–6.96)

5.90 (5.20–7.40)

< 0.01

hs-CRP, mg/L

0.73 (0.44–1.30)

3.80 (2.60–5.42)

0.80 (0.45–1.21)

3.70 (2.60–5.10)

< 0.01

High school education or above, n (%)

109 (17.8)

39 (13.2)

267 (16.4)

172 (17.7)

0.28

Alcohol drinking, n (%)

100 (16.3)

51 (17.3)

312 (19.2)

171 (17.6)

0.41

Smoking, n (%)

116 (18.9)

62 (21.0)

314 (19.3)

203 (20.9)

0.67

Salt intake > 10 g/day, n (%)

33 (5.4)

11 (3.7)

94 (5.8)

60 (6.2)

0.45

Physical activity, n (%)

370 (60.4)

177 (60.0)

1090 (67.0)

616 (63.3)

< 0.01

Risk score, %

28 (19–40)

32 (23–45)

31 (22–45)

37 (28–52)

< 0.01

Hypertension, n (%)

530 (86.5)

266 (90.2)

1443 (88.6)

893 (91.8)

< 0.01

Diabetes mellitus, n (%)

153 (25.0)

70 (23.7)

467 (28.7)

319 (32.8)

< 0.01

Antihypertensive medication use, n (%)

445 (72.6)

227 (76.9)

1209 (74.3)

750 (77.1)

0.16

Antidiabetic medication use, n (%)

66 (10.8)

29 (9.8)

199 (12.2)

129(13.3)

0.29

Antiplatelet medication use, n (%)

254 (41.4)

126 (42.7)

580 (35.6)

343 (35.3)

< 0.01

Properties of statins

    

0.03

 Lipophilic

367(59.9)

181 (61.4)

1058 (65.0)

644 (66.2)

 

 Hydrophilic

35 (5.7)

9(3.1)

90 (5.5)

42 (4.3)

 

 Both of all

211 (34.4)

105(35.6)

480 (29.5)

287 (29.5)

 

MPR ≥ 80%

100 (16.3)

40 (13.6)

338 (20.8)

198 (20.3)

< 0.01

  1. Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high-sensitivity C-reactive protein; LDL-C, low-density lipoprotein cholesterol; MPR, medication possession ratio; RCIR, residual cholesterol and inflammatory risk; RCR, residual cholesterol risk; RIR, residual inflammatory risk; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides.