Skip to main content

Table 2 Association between Metabolic Phenotypes and Cardiovascular Events

From: Cardiovascular risk of metabolically healthy obesity in two european populations: Prevention potential from a metabolomic study

 

All (N = 2339)

 

Flemengho (N = 1331)

 

Hortega (N = 1008)

HR (95% CI) *

P

 

HR (95% CI)

P

 

HR (95% CI)

P

New definition

        

MHNW

1 (reference)

  

 1 (reference)

  

 1 (reference)

 

MHOW

1.22 (0.57–2.62)

0.60

 

1.47 (0.42–5.10)

0.54

 

0.98 (0.37–2.63)

0.97

MHO

1.11 (0.36–3.45)

0.86

 

2.34 (0.43–12.82)

0.33

 

0.65 (0.14–3.06)

0.58

MUHNW

3.30 (1.73–6.28)

0.0003

 

3.18 (1.06–9.51)

0.038

 

3.21 (1.44–7.14)

0.004

MUHOW

2.50 (1.34–4.66)

0.004

 

3.37 (1.17–9.74)

0.025

 

1.76 (0.81–3.83)

0.151

MUHO

3.42 (1.81–6.44)

0.0001

 

3.04 (1.01–9.13)

0.047

 

3.39 (1.56–7.37)

0.002

MetS-Based definition

        

MHNW

1 (reference)

  

 1 (reference)

  

 1 (reference)

 

MHOW

0.83 (0.57–1.21)

0.34

 

1.25 (0.69–2.25)

0.47

 

0.63 (0.39–1.01)

0.055

MHO

1.11 (0.69–1.77)

0.68

 

0.75 (0.28–2.01)

0.56

 

1.17 (0.67–2.02)

0.59

MUHNW

2.09 (1.18–3.72)

0.012

 

2.06 (0.92–4.58)

0.078

 

2.06 (0.84–5.04)

0.12

MUHOW

1.57 (1.04–2.37)

0.033

 

1.62 (0.89–2.96)

0.11

 

1.44 (0.79–2.63)

0.23

MUHO

1.83 (1.21–2.79)

0.004

 

1.87 (0.99–3.55)

0.055

 

1.74 (0.99–3.05)

0.054

  1. All HRs were adjusted for sex, age, total physical activity, smoking, and alcohol consumption. * HRs were additionally adjusted for the cohort indicator
  2. Abbreviation: MHNW, metabolically healthy normal weight; MHOW, metabolically healthy overweight; MHO, metabolically healthy obesity; MUHNW, metabolically unhealthy normal weight; MUHOW, metabolically unhealthy overweight; MUHO, metabolically unhealthy obesity; HR, hazard ratio.
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840