| Number of mental disorders | p-value | p for trend | |||
---|---|---|---|---|---|---|
 | 0 | 1 | 2 | ≥ 3 | ||
n | 1,660,732 | 503,414 | 201,357 | 81,883 | Â | Â |
Age, years | 54.84 ± 12.16 | 60.16 ± 11.36 | 62.63 ± 10.77 | 63.46 ± 10.6 | < 0.0001 | < 0.0001 |
Age group, years |  |  |  |  | < 0.0001 | < 0.0001 |
< 40 | 172,310 (10.38) | 18,404 (3.66) | 3617 (1.8) | 1053 (1.29) |  |  |
40–64 | 1,116,744 (67.24) | 297,779 (59.15) | 105,680 (52.48) | 40,678 (49.68) |  |  |
≥ 65 | 371,678 (22.38) | 187,231 (37.19) | 92,060 (45.72) | 40,152 (49.04) |  |  |
Sex |  |  |  |  | < 0.0001 | < 0.0001 |
Men | 1,145,066 (68.95) | 244,885 (48.64) | 78,081 (38.78) | 28,114 (34.33) | Â | Â |
Women | 515,666 (31.05) | 258,529 (51.36) | 123,276 (61.22) | 53,769 (65.67) | Â | Â |
Income, Q1 (Lowest) | 341,567 (20.57) | 108,084 (21.47) | 44,733 (22.22) | 19,073 (23.29) | < 0.0001 | < 0.0001 |
Smoking |  |  |  |  | < 0.0001 | < 0.0001 |
Non | 811,873 (48.89) | 324,409 (64.44) | 142,901 (70.97) | 59,766 (72.99) | Â | Â |
Ex | 337,898 (20.35) | 81,607 (16.21) | 27,241 (13.53) | 9642 (11.78) | Â | Â |
Current | 510,961 (30.77) | 97,398 (19.35) | 31,215 (15.5) | 12,475 (15.24) | Â | Â |
Drinking |  |  |  |  | < 0.0001 | < 0.0001 |
Non | 820,369 (49.4) | 333,872 (66.32) | 151,442 (75.21) | 65,795 (80.35) | Â | Â |
Mild | 640,898 (38.59) | 131,264 (26.07) | 39,407 (19.57) | 12,808 (15.64) | Â | Â |
Heavy | 199,465 (12.01) | 38,278 (7.6) | 10,508 (5.22) | 3280 (4.01) | Â | Â |
Regular exercise | 349,544 (21.05) | 104,194 (20.7) | 40,210 (19.97) | 15,632 (19.09) | < 0.0001 | < 0.0001 |
Hypertension | 861,072 (51.85) | 307,321 (61.05) | 131,726 (65.42) | 54,076 (66.04) | < 0.0001 | < 0.0001 |
Dyslipidemia | 629,360 (37.9) | 231,149 (45.92) | 102,340 (50.83) | 44,041 (53.79) | < 0.0001 | < 0.0001 |
CKD | 146,018 (8.79) | 65,575 (13.03) | 32,686 (16.23) | 15,114 (18.46) | < 0.0001 | < 0.0001 |
CVD | 23,244 (1.4) | 12,928 (2.57) | 7307 (3.63) | 3862 (4.72) | < 0.0001 | < 0.0001 |
DM Duration, ≥ 5 years | 446,980 (26.91) | 179,791 (35.71) | 80,347 (39.9) | 33,450 (40.85) | < 0.0001 | < 0.0001 |
Insulin | 105,866 (6.37) | 52,216 (10.37) | 28,176 (13.99) | 13,883 (16.95) | < 0.0001 | < 0.0001 |
OHA, ≥ 3 types | 212,974 (12.82) | 83,483 (16.58) | 36,545 (18.15) | 15,057 (18.39) | < 0.0001 | < 0.0001 |
Depression | 0 (0) | 96,242 (19.12) | 117,533 (58.37) | 80,775 (98.65) | < 0.0001 | < 0.0001 |
Bipolar | 0 (0) | 1159 (0.23) | 1739 (0.86) | 4386 (5.36) | < 0.0001 | < 0.0001 |
Schizophrenia | 0 (0) | 3394 (0.67) | 2867 (1.42) | 4051 (4.95) | < 0.0001 | < 0.0001 |
Insomnia | 0 (0) | 117,535 (23.35) | 113,063 (56.15) | 79,832 (97.5) | < 0.0001 | < 0.0001 |
Anxiety | 0 (0) | 285,084 (56.63) | 167,512 (83.19) | 80,530 (98.35) | < 0.0001 | < 0.0001 |
BMI, kg/m2 | 25.11 ± 3.39 | 24.98 ± 3.36 | 24.85 ± 3.4 | 24.72 ± 3.46 | < 0.0001 | < 0.0001 |
Waist Circumference, cm | 85.53 ± 8.6 | 85.08 ± 8.62 | 84.84 ± 8.74 | 84.67 ± 8.9 | < 0.0001 | < 0.0001 |
SBP, mmHg | 129.18 ± 15.76 | 128.77 ± 15.78 | 128.47 ± 15.82 | 127.51 ± 15.89 | < 0.0001 | < 0.0001 |
DBP, mmHg | 79.55 ± 10.32 | 78.41 ± 10.06 | 77.89 ± 10.06 | 77.43 ± 10.11 | < 0.0001 | < 0.0001 |
Fasting glucose, mg/dL | 148.29 ± 47.69 | 140.58 ± 44.81 | 136.98 ± 44.81 | 134.86 ± 45.52 | < 0.0001 | < 0.0001 |
Total cholesterol, mg/dL | 198.21 ± 42.38 | 195.19 ± 42.81 | 193.86 ± 43.45 | 193.7 ± 44.38 | < 0.0001 | < 0.0001 |
HDL-C, mg/dL | 51.92 ± 22.92 | 52.29 ± 24.34 | 52.51 ± 25.16 | 52.52 ± 26.31 | < 0.0001 | < 0.0001 |
LDL-C, mg/dL | 111.83 ± 41.12 | 111.02 ± 40.94 | 110.25 ± 41.5 | 110.04 ± 41.73 | < 0.0001 | < 0.0001 |
eGFR | 86.75 ± 36.72 | 83.82 ± 35.27 | 81.78 ± 34.94 | 80.55 ± 34.54 | < 0.0001 | < 0.0001 |
TG | 149.71 (149.57–149.84) | 141.21 (140.99–141.42) | 139.08 (138.75–139.41) | 139.98 (139.47–140.5) | < 0.0001 | < 0.0001 |