Skip to main content

Table 1 Demographic data

From: CT-derived fractional flow reserve for prediction of major adverse cardiovascular events in diabetic patients

 

Training set

Internal validation set

p#

External test set

p*

(n = 957)

(n = 411)

(n = 429)

Age (years)

62.0 [55.0–69.0]

61.0 [54.0–69.0]

0.723

61.0 [54.0–68.0]

0.162

Males, n (%)

536 (56.0)

243 (59.1)

0.314

252 (58.7)

0.456

BMI, kg/m2

24.4 [22.5–26.8]

24.2 [22.3–26.4]

0.126

25.0 [22.6–27.3]

0.010

Course of diabetes (years)

10.0 [4.00–16.0]

10.0 [3.00–15.0]

0.147

10.0 [3.00–16.0]

0.310

Hypertension, n (%)

533 (55.7)

218 (53.0)

0.398

242 (56.4)

0.571

Dyslipidemia, n (%)

543 (56.7)

249 (60.6)

0.207

312 (72.7)

 < 0.001

Current smoking, n (%)

300 (31.3)

122 (29.7)

0.584

128 (29.8)

0.766

Fast glucose (mmol/L)

7.00 [5.50–9.55]

6.80 [5.50–9.49]

0.484

7.67 [6.00–10.8]

 < 0.001

HbA1c (%)

8.40 [7.20–10.0]

8.40 [7.10–10.1]

0.463

8.50 [7.20–10.3]

0.525

Radiation dose, mSv

1.92 [1.24–2.60]

1.86 [1.21–2.52]

0.375

2.49 [1.70–4.85]

 < 0.001

CT-FFR ≤ 0.80, n (%)

73 (7.63)

41 (9.98)

0.182

26 (6.06)

0.103

Obstructive CAD, n (%)

286 (29.9)

127 (30.9)

0.756

90 (21.0)

0.001

CAD-RADS, n (%):

  

0.191

 

0.001

 0

238 (24.9)

96 (23.4)

 

139 (32.4)

 

 1

219 (22.9)

75 (18.2)

 

101 (23.5)

 

 2

214 (22.4)

113 (27.5)

 

99 (23.1)

 

 3

172 (18.0)

75 (18.2)

 

59 (13.8)

 

 4A

103 (10.8)

43 (10.5)

 

27 (6.29)

 

 4B

9 (0.94)

8 (1.95)

 

2 (0.47)

 

 5

2 (0.21)

1 (0.24)

 

2 (0.47)

 

CACS

  

0.415

 

0.800

 0

427 (44.6)

167 (40.6)

 

191 (44.5)

 

 0–100

343 (35.8)

164 (39.9)

 

157 (36.6)

 

 100–400

120 (12.5)

55 (13.4)

 

54 (12.6)

 

  > 400

67 (7.00)

25 (6.08)

 

27 (6.29)

 

HRP, n (%)

272 (28.4)

118 (28.7)

0.966

101 (23.5)

0.131

LAP, n (%)

277 (28.9)

120 (29.2)

0.977

97 (22.6)

0.034

PR, n (%)

505 (52.8)

226 (55.0)

0.487

225 (52.4)

0.706

SC, n (%)

58 (6.06)

27 (6.57)

0.814

23 (5.36)

0.759

NRS, n (%)

96 (10.0)

46 (11.2)

0.583

28 (6.53)

0.047

Microvascular complications, n (%)

694 (72.5)

288 (70.1)

0.392

330 (76.9)

0.072

MACE, n (%)

65 (6.79)

35 (8.52)

0.313

29 (6.76)

0.489

  1. BMI, body mass index; CACS, Coronary Artery Calcium Scoring; CAD, Coronary artery disease; CAD-RADS, Coronary Artery Disease—Reporting and Data System; CT-FFR, computed tomography fractional flow reserve; HbA1c, hemoglobin A1c; HRP, high-risk plaque; LAP, low-attenuation plaque; MACE, major adverse cardiac events. NRS, napkin-ring sign; PR, positive remodeling; SC, spotty calcification
  2. P#: the p between Training set and Internal validation set, P*: the p among the three cohorts
  3. Values are mean ± SD, n (%), or median (IQR). SD, standard deviation
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840