Fig. 2

Representative cases of diabetic patients with and without MACE. (A) CCTA of a 63-year-old male with stable angina showed multiple obstructive stenosis at proximal and middle LAD. Plaque characterization revealed the presence of LAP for the proximal lesion (blue content) and the distal CT-FFR value was 0.63. The total points of the proposed nomogram were 185. This patient underwent late revascularization of proximal LAD lesion 2.29 years later due to aggravated angina symptom. (B) CCTA of a 79-year-old male with stable angina showed mild stenosis at proximal LAD. Plaque characterization revealed the absence of any HRP feature and the distal CT-FFR value was 0.97. The total points of the proposed nomogram were 55. The patient did not develop MACE at a follow-up of 2.72 years. CCTA = coronary computed tomography angiography; CT-FFR = computed tomography fractional flow reserve; HRP = high-risk plaque; LAP = low-attenuation plaque; LAD = left anterior descending; MACE = major adverse cardiac events