Skip to main content

Table 3 Association between glucose/GA ratio and all-cause and cardiovascular mortality according to diabetes status

From: Prognostic implication of stress hyperglycemia in patients with acute coronary syndrome undergoing percutaneous coronary intervention

Outcome

Diabetes (n = 2394)

No diabetes (n = 2796)

 

Cases, No

Incidence Rate*

HR (95% CI)

Cases, No

Incidence Rate

HR (95% CI)

Model 1 a

Model 2 b

Model 3 c

Model 1 a

Model 2 b

Model 3 c

All-cause mortality

Glucose/GA ratio, quartilesd

 Q1

50

25.6

3.49 (1.77–6.89)

3.30 (1.67–6.52)

3.19 (1.55–6.56)

57

23.0

1.18 (0.79–1.74)

1.11 (0.74–1.68)

1.10 (0.71–1.70)

 Q2

10

6.4

1 [Reference]

1 [Reference]

1 [Reference]

45

15.4

1 [Reference]

1 [Reference]

1 [Reference]

 Q3

35

19.6

3.22 (1.59–6.50)

3.14 (1.55–6.38)

3.04 (1.44–6.42)

36

12.4

0.96 (0.62–1.49)

1.04 (0.67–1.62)

0.98 (0.61–1.58)

 Q4

59

21.5

3.82 (1.95–7.47)

3.37 (1.70–6.65)

3.36 (1.64–6.91)

21

12.3

1.24 (0.73–2.09)

1.14 (0.67–1.94)

1.11 (0.64–1.94)

Cardiovascular mortality

Glucose/GA ratio, quartiles

 Q1

33

16.9

4.58 (1.79–11.75)

4.40 (1.71–11.30)

4.18 (1.61–10.88)

27

10.9

1.08 (0.61–1.88)

1.02 (0.57–1.83)

0.87 (0.46–1.61)

 Q2

5

3.2

1 [Reference]

1 [Reference]

1 [Reference]

23

7.9

1 [Reference]

1 [Reference]

1 [Reference]

 Q3

20

11.2

3.68 (1.38–9.80)

3.51 (1.31–9.43)

3.46 (1.28–9.36)

18

6.2

0.95 (0.51–1.76)

1.09 (0.58–2.04)

1.01 (0.52–1.97)

 Q4

38

13.9

4.96 (1.95–12.62)

4.30 (1.67–11.04)

3.91 (1.50–10.17)

13

7.6

1.52 (0.77–3.03)

1.51 (0.74–3.07)

1.32 (0.63–2.75)

  1. CI, confidence interval; GA, glycated albumin; and HR, hazard ratio
  2. *per 1000 person-years
  3. aModel 1 was adjusted for age and sex
  4. bModel 2 was adjusted as model 1 plus BMI, smoking status, hypertension, dyslipidemia, previous myocardial infarction, previous PCI, previous stroke, and AMI
  5. cModel 3 was adjusted as model 2 plus left main coronary artery or three‑vessel disease, eGFR, SBP, heart rate, LVEF < 50%, hs-CRP, albumin, hemoglobin, ACEI/ARB at discharge, and β-blocker at discharge
  6. dQuartiles of glucose/GA ratio, Q1 < 0.334, Q2 = 0.334–0.384, Q3 = 0.385–0.442, Q4 > 0.442
  7. P for interaction between glucose/GA ratio and diabetes group for all-cause mortality was 0.023 in Model 1, 0.033 in Model 2, and 0.038 in Model 3
  8. P for interaction between glucose/GA ratio and diabetes group for cardiovascular mortality was 0.075 in Model 1, 0.088 in Model 2, and 0.061 in Model 3