Skip to main content
Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways

Fig. 2

Hyper- and hypomethylation changes affect different functional targets during development. a Line plots depicting the scaled methylation patterns at 0, 6 and 12 months of the six clusters identified. b At the top, barplots showing the number of DMPs for each cluster. At the bottom, barplots of the number of associated genes by cluster. c Barplots showing the proportion of significant gene sets (P < 0.05, grey; FDR < 0.05, red) found in the enrichment analyses for each cluster and type of MSigDb database. d Bubble plots showing the top 5 most significant GO BP, CGP and REACTOME gene sets (FDR < 0.05) for clusters 1, 2 and 5

Back to article page