Fig. 5From: Efficacy of antihyperglycemic therapies on cardiovascular and heart failure outcomes: an updated meta-analysis and meta-regression analysis of 35 randomized cardiovascular outcome trialsAssociation between heart failure (HF) risk and A HbA1c reduction or B bodyweight change. The thicker line shows meta-regression with 95% CI as shading. The circle size of each trial inversely reflects the study weight. HbA1c glycated hemoglobin, CI confidence interval, Ln(RR) estimated log risk ratioBack to article page