Dyslipidemia | P | Type 2 diabetes | P | Hypertension | P | Combined mediation effect | P | |
---|---|---|---|---|---|---|---|---|
Proportion mediated, % (95% CI) | Proportion mediated, % (95% CI) | Proportion mediated, % (95% CI) | Proportion mediated, % (95% CI) | |||||
TyG indexb | ||||||||
Cardiovascular disease | 45.8 (34.4–57.7) | < 0.001 | 27.0 (19.5–36.1) | < 0.001 | 15.0 (9.8–22.2) | < 0.001 | 56.5 (41.7–70.2) | < 0.001 |
Coronary heart disease | 36.1 (28.0–44.9) | < 0.001 | 20.6 (15.4–26.9) | < 0.001 | 11.1 (7.2–16.7) | < 0.001 | 43.6 (33.6–54.1) | < 0.001 |
TG/HDL-C ratiob | ||||||||
Cardiovascular disease | 40.0 (32.8–47.7) | < 0.001 | 11.8 (9.1–15.2) | < 0.001 | 13.3 (9.8–17.8) | < 0.001 | 46.6 (38.0–55.4) | < 0.001 |
Coronary heart disease | 33.5 (27.9–39.6) | < 0.001 | 9.6 (7.5–12.3) | < 0.001 | 10.6 (7.8–14.3) | < 0.001 | 38.3 (31.8–45.4) | < 0.001 |