Fig. 2

Number of patients undergoing CAC score measurement and stress myocardial scintigraphy; detected with silent myocardial ischemia, coronary stenoses, and who had revascularization procedures according to various screening strategies. Part A: Screening all patients at very high risk is considered as the reference strategy. Part B: Screening the patients at very high risk and with a high CAC score (dotted bars: CAC score ≥ 400 Agatston units (AU), hatched bars: CAC score ≥ 100 AU). Part C: Screening the patients at very high risk and with severe TOD without CAC measurement (solid bars), with severe TOD and CAC score ≥ 400 AU (dotted bars) or ≥ 100 AU (hatched bars). Part D: Screening the patients at very high risk and with any TOD (severe or mild) without CAC measurement (solid bars), with any TOD and CAC score ≥ 400 AU (dotted bars) or ≥ 100 AU (hatched bars). The sensitivity to detect the patients with silent myocardial ischemia, coronary stenosis, and who would have had revascularization procedures is shown for strategies B–D, as compared to screening all patients at very high risk (strategy A). CAC score coronary artery calcium score, CS: coronary stenosis, SMI silent myocardial ischemia, TOD target organ damage. ^aThirty of the 39 patients with SMI underwent a coronary angiography. *CAC not measured when only the presence of TOD is considered