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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: General versus central adiposity as risk factors for cardiovascular-related outcomes in a high-risk population with type 2 diabetes: a post hoc analysis of the REWIND trial

Fig. 1

Association of BMI, WHR, WC, and WC adjusted for HC with (A) MACE-3, (B) CVD-related mortality, (C) all-cause mortality, and (D) HF requiring hospitalization or urgent care. Results are estimated from Cox proportional hazard regression models. Results are presented per 1 SD increase (WHR 0.08; BMI 5.8 kg/m2; WC 13.4 cm; HC 12.7 cm). All obesity measures were evaluated, after adjustment for age and sex (Step 1 of the statistical analysis approach). Those that were significant (p < 0.05) progressed to Step 2 (adjustment for age, sex, and selected baseline factors from the LASSO selection process), otherwise the process stopped after Step 1 (*). BMI body mass index, CI confidence interval, CVD cardiovascular disease, HC hip circumference, HF heart failure, HR hazard ratio; MACE = major adverse cardiovascular events, SD standard deviation; WC waist circumference, WHR waist-to-hip ratio

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Cardiovascular Diabetology

ISSN: 1475-2840