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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Targeting high glucose-induced epigenetic modifications at cardiac level: the role of SGLT2 and SGLT2 inhibitors

Fig. 1

Effects of empa on cell viability, oxidative stress and inflammation in cardiomyocytes exposed to hyperglycemia. A Cell viability exanimated using CCK-8 assay and B, Intracellular ROS levels, measured using a ROS detection assay kit. C–E, qRT-PCR for NF-kB, SOD2 and IL-6 in AC16 cells exposed to NG concentration (4.5 mM) (NG), cells exposed to high glucose concentration (HG), and cells co-treated with HG and 0.5 nM of EMPA (HG + Empa). β-Actin was used as internal control. The fold increase of mRNA expression compared with NG was calculated using the 2−ΔΔCt method

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Cardiovascular Diabetology

ISSN: 1475-2840