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Table 3 Adjusted HR for MACE during 6-year follow-up according to baseline categories of abnormal glucose metabolism by IEC HbA1c-based definition

From: HbA1c-based rather than fasting plasma glucose-based definitions of prediabetes identifies high-risk patients with angiographic coronary intermediate lesions: a prospective cohort study

 

Event/Total (%)

HR (95% CI)

P value

Model 1

 NGT

41/527 (7.78)

1 (reference)

1 (reference)

 Prediabetes

58/419 (13.84)

1.705 (1.143, 2.543)

0.0090

 DM

98/586 (16.72)

2.173 (1.509, 3.129)

 < .0001

Model 2

 NGT

41/527 (7.78)

1 (reference)

1 (reference)

 Prediabetes

58/419 (13.84)

1.514 (1.011, 2.267)

0.0440

 DM

98/586 (16.72)

2.027 (1.403, 2.927)

0.0002

Model 3

 NGT

41/527 (7.78)

1 (reference)

1 (reference)

 Prediabetes

58/419 (13.84)

1.513 (1.005, 2.277)

0.0471

 DM

98/586 (16.72)

1.870 (1.273, 2.745)

0.0014

  1. Model 1 is univariate analysis
  2. Model 2 adjusted for age and sex
  3. Model 3 adjusted for model 2 plus medical history of hypertension, hyperlipidemia, smoking status, alcoholic consumption, body mass index, heart rate, total cholesterol, LDL, HDL, hsCRP, D-Dimer and triple vessel disease;
  4. MACE major adverse cardiovascular events, IEC  international expert committee, HbA1C glycated haemoglobin, NGT normal glucose tolerance, DM diabetes mellitus, HR hazard ratio, CI confidence interva
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Cardiovascular Diabetology

ISSN: 1475-2840