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Table 1 Comparison of characteristics between T2DM patients with and without CAD

From: Diagnosis of coronary artery disease in patients with type 2 diabetes mellitus based on computed tomography and pericoronary adipose tissue radiomics: a retrospective cross-sectional study

Characteristic

All

Patient with CAD

Patient without CAD

p

n

229

146

83

 

Age (years)

58.79 ± 9.32

60.36 ± 9.01

56.02 ± 9.27

 < 0.001

Male sex, n (%)

139 (60.7)

92 (63.0)

47 (56.6)

0.341

Body mass index (kg/m2)

26.00 [23.68; 27.70]

26.00 [23.60; 27.40]

25.70 [23.80; 28.10]

0.608

Obesity, n (%)

50 (21.8)

28 (19.2)

22 (26.5)

0.197

Smoking, n (%)

51 (22.3)

35 (24.0)

16 (19.3)

0.412

Drinking, n (%)

28 (12.2)

21 (14.4)

7 (8.4)

0.186

Hypertension, n (%)

142 (62.0)

100 (68.5)

42 (50.6)

0.007

Dyslipidaemia, n (%)

25 (10.9)

22 (15.1)

3 (3.6)

0.008

Family history, n (%)

20 (8.7)

15 (10.3)

5 (6.0)

0.274

Time since T2DM diagnosis (years)

7.00 [2.00; 12.25]

10.00 [4.00; 15.00]

3.00 [0.00; 8.00]

 < 0.001

Aspirin, n (%)

12 (5.2)

9 (6.2)

3 (3.6)

0.405

Statin, n (%)

93 (40.6)

60 (41.1)

33 (39.8)

0.843

Metformin, n (%)

108 (47.2)

69 (47.3)

39 (47.0)

0.968

Insulin, n (%)

96 (41.9)

59 (40.4)

37 (44.6)

0.539

Oral antihyperglycemic drugs, n (%)

195 (85.2)

126 (86.3)

69 (83.1)

0.517

HDL-cholesterol (mg/dL)

0.99 [0.87; 1.12]

0.98 [0.86; 1.10]

1.02 [0.91; 1.17]

0.102

LDL-cholesterol (mg/dL)

3.43 [3.01; 3.79]

3.58 [3.09; 3.97]

3.28 [2.77; 3.53]

 < 0.001

Total cholesterol (mg/dL)

5.28 [3.91; 6.00]

5.44 [3.99; 6.17]

4.66 [3.78; 5.78]

0.031

Triglyceride (mg/dL)

1.86 [0.65; 2.80]

0.83 [0.52; 2.72]

2.09 [0.93; 2.87]

0.003

Fast glucose (mmol/L)

9.60 [7.90; 12.21]

10.20 [8.30; 12.70]

8.80 [7.23; 11.28]

0.001

HbA1c (%)

7.70 [6.80; 9.10]

8.10 [7.40; 9.30]

7.00 [6.33; 8.43]

 < 0.001

Retinopathy, n (%)

132 (57.6)

86 (58.9)

46 (55.4)

0.608

Neuropathy, n (%)

215 (93.9)

137 (93.8)

78 (94.0)

0.966

Peripheral arterial occlusive disease, n (%)

175 (76.4)

113 (77.4)

62 (74.7)

0.644

Nephropathy, n (%)

83 (36.2)

54 (37.0)

29 (34.9)

0.757

CACS

28.69 [4.15; 127.07]

70.68 [15.66; 224.41]

7.48 [1.61; 24.60]

 < 0.001

PAT volume (mL)

178.44 [135.41; 230.29]

180.14 [138.64; 243.55]

173.55 [131.60; 212.33]

0.289

CT-FFR

0.83 [0.71; 0.90]

0.75 [0.64; 0.85]

0.90 [0.86; 0.94]

 < 0.001

DS (%)

48.00 [22.00; 67.00]

57.50 [34.00; 72.00]

28.00 [0.00; 52.00]

 < 0.001

RCA-PCATA (HU)

− 84.13 ± 9.64

− 80.94 ± 8.84

− 89.75 ± 8.38

 < 0.001

LAD-PCATA (HU)

− 82.90 ± 8.59

− 80.50 [− 87.00; − 74.00]

− 86.00 [− 91.00; − 81.00]

 < 0.001

LCX-PCATA (HU)

− 80.00 [− 87.00; − 74.00]

− 78.68 ± 8.06

− 84.00 ± 7.38

 < 0.001

  1. Values are mean ± standard deviation, median [25th and 75th percentile] or n (%). p values signify statistical significance and reflect the differences between patients with and without CAD. Obesity was defined as a body mass index ≥ 28 kg/m2
  2. T2DM type 2 diabetes mellitus, CAD coronary artery disease, HDL high-density lipoprotein, LDL low-density lipoprotein, HbA1c glycated haemoglobin, CACS coronary artery calcium score, PAT pericardial adipose tissue, CT-FFR computed tomography-based fractional flow reserve, DS diameter stenosis, PCATA pericoronary adipose tissue attenuation
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Cardiovascular Diabetology

ISSN: 1475-2840