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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: Deletion of Tbc1d4/As160 abrogates cardiac glucose uptake and increases myocardial damage after ischemia/reperfusion

Fig. 2

Deletion of Tbc1d4 leads to impaired in vivo cardiac glucose uptake. A [18F]-fluorodeoxy-D-glucose positron emission tomography (PET) scan technique was applied in order to visualize glucose uptake into the heart (white arrow) for male Tbc1d4-deficient and wild type mice on a Chow-diet. B Quantification of cardiac glucose uptake over time with corresponding (C) area under the curve (AUC) calculation. Data presented as mean ± SEM (n = 4). Statistical analysis was performed using unpaired two-tailed student’s t-Test (C; WT vs. D4KO: *p < 0.05). WT wild type, D4KO Tbc1d4-knockout

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