Controls (n = 67) | T2DM without anemia (n = 174) | T2DM with anemia (n = 62) | P value | |
---|---|---|---|---|
Demographics | ||||
Male, n (%) | 34 (50.7) | 89(51.1) | 33 (53.2) | 0.952 |
Age, years | 56.73 ± 9.66 | 57.07 ± 10.51 | 63.29 ± 12.23*§ | 0.000 |
BMI (kg/m2) | 23.41 ± 3.06 | 24.54 ± 2.95* | 24.23 ± 3.34 | 0.038 |
Heart rate (beats/min) | 74 ± 10 | 80 ± 16* | 81 ± 15* | 0.016 |
SBP (mmHg) | 118 ± 12 | 130 ± 18* | 129 ± 19* | 0.000 |
DBP (mmHg) | 74 ± 9 | 79 ± 13* | 77 ± 13 | 0.037 |
Smoking history, n (%) | 15 (22.38) | 43 (24.70) | 21 (33.87) | 0.273 |
Diabetes duration, years | – | 6 (3.0, 10.0) | 5 (2.0, 9.0) | 0.272 |
Laboratory data | ||||
Hb, (g/L) | 142 ± 13 | 139 ± 12 | 107 ± 12*§ | 0.000 |
HbA1c, % | – | 7.41 ± 1.75 | 7.19 ± 1.17 | 0.280 |
TG (mmol/L) | 1.28 (0.99, 1.65) | 1.49 (1.01, 2.19) | 1.25 (0.96, 1.71)* | 0.042 |
TC (mmol/L) | 4.81 (3.97, 5.24) | 4.19 (3.33, 4.90)* | 3.43 (2.99, 4.45)*§ | 0.000 |
HDL (mmol/L) | 1.29 (1.12, 1.53) | 1.17 (0.96, 1.42)* | 1.14 (0.88, 1.39)* | 0.001 |
LDL (mmol/L) | 2.91 (2.24, 3.38) | 2.26 (1.71, 2.94)* | 1.74 (1.41, 2.37)*§ | 0.000 |
eGFR (mL/min/1.73 m2) | 93.78 ± 15.13 | 87.53 ± 19.46 | 70.67 ± 22.37*§ | 0.000 |
Creatinine, umol/L | 71.12 ± 15.43 | 76.15 ± 22.34* | 94.06 ± 31.25*§ | 0.000 |
Complications, n (%) | ||||
Nephropathy | – | 16 (9.20) | 18 (29.03)§ | 0.000 |
Retinopathy | – | 13 (7.47) | 4 (6.45) | 1.000 |
Peripheral vascular disease | – | 35 (20.11) | 14 (27.42) | 0.681 |
Neuropathy | – | 33 (18.97) | 6 (9.68) | 0.091 |
Medications, n (%) | ||||
Insulin | – | 32 (18.39) | 12 (19.35) | 0.979 |
Biguanides | – | 72 (41.38) | 24 (38.71) | 0.713 |
Sulfonylureas | – | 31 (17.82) | 6 (9.68) | 0.130 |
α‑Glucosidase inhibitor | – | 34 (19.54) | 8(12.90) | 0.241 |
Others | – | 25 (14.37) | 8 (12.90) | 0.775 |
No | – | 37 (21.26) | 11 (17.74) | 0.554 |