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Table 1 Baseline characteristics of the study population

From: The worsening effect of anemia on left ventricular function and global strain in type 2 diabetes mellitus patients: a 3.0 T CMR feature tracking study

 

Controls (n = 67)

T2DM without anemia (n = 174)

T2DM with anemia (n = 62)

P value

Demographics

 Male, n (%)

34 (50.7)

89(51.1)

33 (53.2)

0.952

 Age, years

56.73 ± 9.66

57.07 ± 10.51

63.29 ± 12.23*§

0.000

 BMI (kg/m2)

23.41 ± 3.06

24.54 ± 2.95*

24.23 ± 3.34

0.038

 Heart rate (beats/min)

74 ± 10

80 ± 16*

81 ± 15*

0.016

 SBP (mmHg)

118 ± 12

130 ± 18*

129 ± 19*

0.000

 DBP (mmHg)

74 ± 9

79 ± 13*

77 ± 13

0.037

 Smoking history, n (%)

15 (22.38)

43 (24.70)

21 (33.87)

0.273

 Diabetes duration, years

6 (3.0, 10.0)

5 (2.0, 9.0)

0.272

Laboratory data

 Hb, (g/L)

142 ± 13

139 ± 12

107 ± 12*§

0.000

 HbA1c, %

7.41 ± 1.75

7.19 ± 1.17

0.280

 TG (mmol/L)

1.28 (0.99, 1.65)

1.49 (1.01, 2.19)

1.25 (0.96, 1.71)*

0.042

 TC (mmol/L)

4.81 (3.97, 5.24)

4.19 (3.33, 4.90)*

3.43 (2.99, 4.45)*§

0.000

 HDL (mmol/L)

1.29 (1.12, 1.53)

1.17 (0.96, 1.42)*

1.14 (0.88, 1.39)*

0.001

 LDL (mmol/L)

2.91 (2.24, 3.38)

2.26 (1.71, 2.94)*

1.74 (1.41, 2.37)*§

0.000

 eGFR (mL/min/1.73 m2)

93.78 ± 15.13

87.53 ± 19.46

70.67 ± 22.37*§

0.000

 Creatinine, umol/L

71.12 ± 15.43

76.15 ± 22.34*

94.06 ± 31.25*§

0.000

Complications, n (%)

 Nephropathy

16 (9.20)

18 (29.03)§

0.000

 Retinopathy

13 (7.47)

4 (6.45)

1.000

 Peripheral vascular disease

35 (20.11)

14 (27.42)

0.681

 Neuropathy

33 (18.97)

6 (9.68)

0.091

Medications, n (%)

 Insulin

32 (18.39)

12 (19.35)

0.979

 Biguanides

72 (41.38)

24 (38.71)

0.713

 Sulfonylureas

31 (17.82)

6 (9.68)

0.130

 α‑Glucosidase inhibitor

34 (19.54)

8(12.90)

0.241

 Others

25 (14.37)

8 (12.90)

0.775

 No

37 (21.26)

11 (17.74)

0.554

  1. Data are presented as the mean ± SD, median (Q1, Q3) or number (percentage)
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, Hb hemoglobin, TC total cholesterol, TG triglyceride, HDL high-density lipoprotein, LDL low-density lipoprotein cholesterol, eGFR estimate glomerular filtration rate
  3. *P less than 0.017 vs. controls
  4. §P less than 0.05 vs. T2DM patients without anemia