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Table 1 Characteristics of studies inclcuded in the meta-analysis

From: The impact of triglyceride-glucose index on ischemic stroke: a systematic review and meta-analysis

Study

Country

Study design

Male%

Age (mean ± sd)

Study time

Participants

TyG index condition

Type of outcome

The association of TyG index with risk of ischemic stroke

Wenrui S 2019

China

cross-sectional

40.20%

59.95 ± 10.07

8 M

10,900 from rural areas of northeast China

TyG I

IS Incidence

Anxin Wang 2021

China

prospective cohort

79.62%

51.38 ± 11.45

11.02 Y

97,653 from the Kailuan community in Tangshan City, China

TyG I

IS Incidence

Yang Zhao 2021

China

prospective cohort

40.88%

53.93 ± 11.19

6 Y

11,777 from the Rural Chinese Cohort Study

TyG I

IS Incidence

Qian Liu 2022

China

prospective cohort

79.61%

51.49 ± 12.53

10.33 Y

96,541 from the Kailuan community in Tangshan City, China

TyG I

IS Incidence

Qi Zhao 2021

China

retrospective cohort

73.70%

59.70 ± 9.30

4 Y

1510 individuals diagnosed with NSTE-ACS

TyG II

IS Incidence

Shucheng Si 2021

European

prospective cohort

43.01%

56.00 ± 8.02

4 Y

273,368 from the UK Biobank cohort

TyG I

IS Incidence

Longlong Hu 2022

China

prospective cohort

52.76%

68.77 ± 6.19

1.72 Ys

8487 from the China H-type Hypertension Registry Study

TyG I

IS Incidence

Xianxuan Wang 2022

China

prospective cohort

76.08%

49.03 ± 11.84

9 Y

54,098 from the Kailuan community in Tangshan City, China

TyG I

IS Incidence

The association of TyG index with prognosis among patients with ischemic stroke

Yimo Zhou 2020

China

cohort

63.48%

64.83 ± 11.90

1 Y

16,310 from the China National Stroke Registry II

TyG I

Stroke recurrence, All-cause mortality, Poor functional outcome, Neurologic worsening

Bingjun Zhang 2020

China

retrospective observational

51.60%

66.30 ± 14.20

2 Y

4570 from the eICU Collaborative Research Database (208 United States hospitals)

TyG I

All-cause mortality

Minwoo Lee 2021

Korea

retrospective observational

59.00%

69.50 ± 12.40

4 Y

183 patients from three university-affiliated hospitals

TyG II

Poor functional outcome

Ki-Woong N (a) 2021

Korea

retrospective cross-sectional

59.30%

69.04 ± 11.24

4 Y

305 from the Seoul National University Hospital

TyG IV

Neurologic worsening

Zongyi Hou 2021

China

prospective cohort

63.30%

64.83 ± 12.20

1 Y

12,964 from the China National Stroke Registry II

TyG I

Stroke recurrence, Poor functional outcome, All-cause mortality

Ki-Woong N (b) 2021

Korea

retrospective cross-sectional

58.52%

72.03 ± 5.60

7 Y

176 from the Seoul National University Boramae Medical Center

TyG III

Stroke recurrence

Xiaomeng Yang 2022

China

cohort

62.97%

62.66 ± 14.60

1 Y

1226 from the Abnormal Glucose Regulation in Patients with Acute Stroke across China registry

TyG I

Stroke recurrence, All-cause mortality

Sheng-Feng Lin 2022

China

multicenter prospective cohort

63.68%

69.09 ± 12.23

12 Y

914 clinical data from 30 hospitals in Taiwan were collected and registered in the TTT-AIS registry

TyG III

Poor functional outcome, All-cause mortality

Emma M. S.Toh 2022

Singapore

retrospective cohort

61.50%

65.35 ± 15.60

11.75 Y

698 from a comprehensive stroke center

TyG II

All-cause mortality, Poor functional outcome

Fang Wang 2022

China

retrospective cohort

67.20%

70.70 ± 5.94

1 Y

955 from the Nanjing Stroke Registry Program

TyG I

Stroke recurrence

  1. IS ischemic stroke, NSTE-ACS: non-ST-segment elevation acute coronary syndrome, TTT-AIS The Taiwan thrombolytic therapy for acute ischemic Stroke, M month, Y year, Ys years, TyG I TyG index quartiles, TyG II TyG index dichotomized, TyG III TyG index is divided into three categories, TyG IV TyG index (Uncategorized, count data)