Fig. 2

Adjusted restricted cubic spline analysis for the associations between HDL-P measurements and incident CVD and all-cause mortality. The solid lines are the adjusted log hazard ratios, and the shaded areas are 95% CIs derived from corresponding restricted cubic spline regressions. A knot was located at 10th, 50th (reference value), 90th percentiles for each of the HDL-P measurements. Analyses were adjusted for age, sex, smoking, diabetes duration, systolic blood pressure, body mass index, glycated hemoglobin, estimated glomerular filtration rate, ln (urinary albumin-creatinine ratio), ln (triglycerides), low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, glycoprotein acetyls, oral anti-hyperglycemic drugs, insulin use, renin-angiotensin system blockers, anti-hypertensive drugs, lipid-lowering drugs, and history of cardiovascular disease (for all-cause mortality)