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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Effects of single and multiple sessions of lower body diastole-synchronized compressions using a pulsating pneumatic suit on endothelium function and metabolic parameters in patients with type 2 diabetes: two controlled cross-over studies

Fig. 3

Effects of DSCD/control sessions on interstitial glucose and endothelium function. A: Decrease of interstitial glucose after one DSCD/control session (Study 1) for continuous glucose measures (CGM) i-glucose decremental AUCs. AUC, area under the curve; CGM, continuous glucose measures; Control, simulated session; DSCD, diastole synchronized compression/decompression session at 65 mmHg, i-glucose; interstitial glucose. Decremental AUC illustrates the decrease of i-glucose (CGM recording). Decremental AUCs were calculated for one hour after the start of DSCD/control session (AUC from T60 to T120minutes), for the next hour (T120 to 180 min) and for the 2 hours after the start of DSCD/Control session (T60 to 180 min). No crossover and period effects were observed allowing calculating the variance of the 2 h i-glucose decremental AUC between the control and DSCD (p = 0.02). B: Correlation between i-glucose decremental AUC and ACh CBF AUC5min. AUC; area under the curve, CGM; continuous glucose measures, control, simulated session, DSCD; diastole synchronized compression/decompression session at 65 mmHg; i-glucose, interstitial glucose. Breakfast was eaten 110 min before start of sessions (see Fig. 1). The Spearman’s correlation coefficient (denoted r) was calculated between i-glucose decremental AUC T60-180 and ACh CBF AUC5min after a single 20 min DSCD session. No significant correlation was found before the DSCD/control sessions

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Cardiovascular Diabetology

ISSN: 1475-2840