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Table 3 Stratified analyses of the associations between TSH levels and all-cause mortality among patients with diabetes

From: TSH levels within the normal range and risk of cardiovascular and all-cause mortality among individuals with diabetes

 

Serum TSH levels (mIU/L)

P interaction

Low-normal (0.39–1.30)

Medium-normal (1.30–2.09)

High-normal (2.09–4.60)

Age, years

0.028

  < 60

1.28 (0.78, 2.12)

1

1.73 (1.03, 2.92)

 

  ≥ 60

1.29 (0.96, 1.73)

1

1.18 (0.96, 1.44)

 

Sex

0.420

 Male

1.75 (1.27–2.40)

1

1.44 (1.10, 1.89)

 

 Female

1.11 (0.85, 1.45)

1

1.19 (1.01, 1.45)

 

Race/ethnicity

0.674

 Non-Hispanic white

1.62 (1.23, 2.15)

1

1.50 (1.16, 1.94)

 

 Others

1.10 (0.89, 1.37)

1

0.99 (0.74, 1.32)

 

Smoking status

0.154

 Never

1.30 (0.93, 1.81)

1

1.33 (1.02, 1.74)

 

 Ever or Current

1.50 (1.14, 1.98)

1

1.34 (1.04, 1.72)

 

BMI, kg/m2

0.683

  < 30

1.53 (1.16, 2.02)

1

1.34 (1.05, 1.72)

 

  ≥ 30

1.28 (0.95, 1.73)

1

1.28 (0.93, 1.76)

 

Diabetes duration, years

0.479

  < 10

1.41 (1.10, 1.80)

1

1.30 (1.04, 1.64)

 

  ≥ 10

1.53 (0.99, 2.34)

1

1.42 (1.05, 1.92)

 

eGFR, mL/min/1.73 m2

0.067

  < 60

1.33 (0.93, 1.90)

1

1.40 (1.09, 1.81)

 

  ≥ 60

1.47 (1.12, 1.92)

1

1.23 (0.90, 1.68)

 

History of CVD

0.257

 Yes

1.69 (1.06, 2.69)

1

1.49 (1.04, 2.13)

 

 No

1.39 (1.09, 1.78)

1

1.29 (1.02, 1.64)

 
  1. Data are presented as HR (95% CI). Adjusted for age, sex, race/ethnicity. BMI, education level, family income-poverty ratio, smoking status, drinking status, physical activity, eGFR, HbA1c, TC, HDL-C, diabetes duration, glucose-lowering medications use, history of hypertension, history of CVD, and history of cancer, except for stratifying factors
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Cardiovascular Diabetology

ISSN: 1475-2840