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Table 1 Baseline characteristics of patients with diabetes in NHANES III

From: TSH levels within the normal range and risk of cardiovascular and all-cause mortality among individuals with diabetes

 

Total

Serum TSH levels (mIU/L)

P value

Tertile 1 (0.39–1.30)

Tertile 2 (1.30–2.09)

Tertile 3 (2.09–4.60)

Participants, n

1830

576

642

612

 

 Age, years

58.0 (14.2)

54.3 (15.1)

59.0 (13.8)

60.6 (13.0)

<0.001

 Age ≥ 60

1047 (50.2)

286 (39.0)

359 (51.9)

402 (59.9)

<0.001

 Male

859 (49.2)

273 (52.3)

311 (50.0)

275 (45.3)

0.413

Race/ethnicity

0.040

 Non-Hispanic white

670 (71.6)

177 (65.7)

244 (72.1)

249 (77.1)

 

 Non-Hispanic black

528 (14.2)

202 (17.1)

189 (14.9)

137 (10.6)

 

 Hispanic Mexican

559 (6.1)

169 (6.1)

184 (6.0)

206 (6.2)

 

 Others

73 (8.1)

28 (11.1)

25 (7.1)

20 (6.1)

 

Education level

0.571

 Less than high school

702 (22.4)

215 (25.0)

233 (22.2)

254 (19.9)

 

 High school or equivalent

799 (50.4)

263 (49.5)

291 (51.3)

245 (50.2)

 

 Higher than high school

329 (27.3)

98 (25.6)

118 (26.5)

113 (29.9)

 

Smoking status

0.532

 Never

847 (41.4)

267 (43.1)

296 (39.0)

284 (42.2)

 

 Former

651 (38.6)

196 (34.5)

222 (39.9)

233 (41.4)

 

 Current

332 (20.0)

113 (22.4)

124 (21.1)

95 (16.5)

 

BMI, kg/m2

29.5 (6.2)

29.3 (6.4)

29.4 (6.0)

29.8 (6.2)

0.720

Leisure-time physical activity

0.337

 Inactive

530 (21.5)

171 (24.8)

174 (17.7)

185 (22.3)

 

 Insufficiency active

728 (42.2)

221 (41.4)

248 (43.6)

259 (41.5)

 

 Active

572 (36.3)

184 (33.8)

220 (38.7)

168 (36.2)

 

Diabetes duration, years

0.748

 <10

1391 (79.7)

446 (80.2)

482 (78.5)

463 (80.7)

 

  ≥ 10

439 (20.3)

130 (19.8)

160 (21.5)

149 (19.3)

 

HbA1c, %,

0.757

 <7.0

1085 (64.9)

352 (65.1)

376 (63.3)

357 (66.6)

 

  ≥ 7.0

745 (35.1)

224 (34.9)

266 (36.7)

255 (33.4)

 

eGFR, mL/min/1.73 m2

0.038

 <30

46 (1.7)

15 (1.7)

13 (1.8)

18 (1.7)

 

 30–60

542 (28.8)

142 (25.0)

189 (26.9)

211 (34.8)

 

  ≥ 60

1242 (69.5)

419 (73.3)

440 (71.4)

383 (63.5)

 

Urinary iodine, μg/L

0.146

 <100

568 (34.2)

165 (33.1)

223 (39.0)

180 (30.1)

 

 100–187

597 (34.0)

203 (34.0)

181 (29.2)

213 (39.0)

 

  ≥ 187

598 (31.8)

186 (32.9)

213 (31.7)

199 (30.8)

 

TPO-Ab, IU/mL

<0.001

 <0.5

1642 (89.9)

535 (92.6)

599 (94.5)

508 (82.2)

 

  ≥ 0.5

188 (10.1)

41 (7.4)

43 (5.5)

104 (17.8)

 

HEI score

65.1 (14.1)

63.9 (14.7)

65.0 (14.1)

66.3 (13.4)

0.274

HDL-C, mg/dL

47.0 (15.8)

47.9 (15.2)

47.1 (14.6)

46.0 (17.6)

0.565

TC, mg/dL

222.2 (49.6)

218.1 (54.8)

224.7 (46.3)

223.5 (47.1)

0.312

Medical conditions

 Hypertension

902 (47.6)

269 (43.6)

310 (48.2)

323 (50.9)

0.208

 Cardiovascular disease

327 (16.1)

80 (12.4)

112 (16.1)

135 (20.0)

0.023

 Cancer

173 (12.7)

51 (10.4)

59 (14.2)

63 (13.3)

0.439

  1. All estimates accounted for sample weights and complex survey designs. Data are presented as numbers (percentages) for categorical variables and mean (standard deviation) for continuous variables. Percentages and means are adjusted for survey weights of NHANES
  2. BMI body mass index, eGFR estimated glomerular filtration rate, HbA1c glycated hemoglobin A1c, HEI healthy eating index, HOMA-IR homeostasis model assessment of insulin resistance, NHANES National Health and Nutrition Examination Survey, TPO-Ab anti-thyroid peroxidase antibody