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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: TSH levels within the normal range and risk of cardiovascular and all-cause mortality among individuals with diabetes

Fig. 2

Dose–response associations between TSH levels and all-cause (A) and CVD (B) mortality risks among euthyroid patients with diabetes. Associations were investigated by multivariable Cox regression models based on restricted cubic splines. Solid lines represent hazard ratios, whereas shaded sections represent 95% CIs. Risk estimates were adjusted for age, sex, race/ethnicity, BMI, education level, family income-poverty ratio, smoking status, drinking status, physical activity, diabetes duration, glucose-lowering medication use, HbA1c, TC, HDL-C, eGFR, history of CVD, history of hypertension, and history of cancer. P-values for the nonlinear association are all < 0.05

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