Fig. 2

Dose–response relationships of baseline arterial stiffness level with incident macrovascular complication stratified by glycemic control and hypertension status. Restricted cubic spline regression model was conducted using 3 knots at the 10th, 50th, and 90th percentiles, using 1200 cm/s as reference. Black solid line represents the hazard ratio and the dashed line represents the 95% CI. The y-axis ranges of A–D are different. Analyses were adjusted for age (continuous), sex, obesity (yes/no), eGFR (continuous), LDL cholesterol (continuous), hypertension (yes/no, if not stratified), glycemic control (good/poor, if not stratified), current smoking (yes/no) and physical activity (yes/no). baPWV, brachial-ankle pulse wave velocity; LDL, low-density lipoprotein; eGFR, estimated glomerular filtration rate