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Table 4 Univariate and Multivariate Cox regression analyses for incident CHD

From: Association of triglyceride–glucose index and traditional risk factors with cardiovascular disease among non-diabetic population: a 10-year prospective cohort study

TyG index

Incident CHD, n (%)

HR (95%CI)

Model 1

Model 2

Model 5

Model 4

Per Unit increase

224 (3.7)

1.599 (1.326–1.928) ***

1.474 (1.209–1.798) ***

1.298 (1.045–1.612) *

1.308 (1.052–1.627) *

Per SD increase

 

1.350 (1.198–1.522) ***

1.282 (1.129–1.456) ***

1.182 (1.029–1.357) *

1.188 (1.033–1.366) *

Quartile 1

33 (2.2)

1 (Reference)

1 (Reference)

1 (Reference)

1 (Reference)

Quartile 2

51 (3.4)

1.559 (1.006–2.416) *

1.372 (0.885–2.127)

1.222 (0.784–1.904)

1.225 (0.785–1.910)

Quartile 3

51 (3.3)

1.530 (0.988–2.371)

1.224 (0.788–1.900)

0.998 (0.635–1.567)

0.999 (0.635–1.570)

Quartile 4

89 (5.8)

2.768 (1.856–4.127) ***

2.171 (1.453–3.243) ***

1.663 (1.091–2.534) *

1.687 (1.105–2.575) *

p for trend

 

 < 0.001

 < 0.001

0.014

0.011

  1. Model 1: unadjusted
  2. Model 2: adjusted for age and gender
  3. Model 5: adjusted for age, tobacco use, physical activity, hypertension, BMI, LDL-C, intake of carbohydrates, use of antihypertensive drugs, and use of antilipemic drugs
  4. Model 4: adjusted for age, gender, WHR, tobacco use, alcohol use, education, physical activity, hypertension, BMI, LDL-C, intake of fat and carbohydrates, use of antihypertensive drugs, and use of antilipemic drugs
  5. CHD coronary heart disease; TyG index triglyceride–glucose index; HR hazard ratio; CI confidence interval; SD standard deviation
  6. *p < 0.05
  7. **p < 0.01
  8. ***p < 0.001
  9. p values in bold are < 0.05