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Table 3 All-cause and cause-specific mortality according to advanced fibrosis

From: The association of fatty liver index and BARD score with all-cause and cause-specific mortality in patients with type 2 diabetes mellitus: a nationwide population-based study

 

N

Death

Duration (PYs)

Incidence rate (per 1000 PY)

Hazard ratio (95% confidence interval)

Model 1

Model 2

All Cause of mortality

 FLI < 60

1,491,740

176,735

11572947.32

15.27

1(Ref.)

1(Ref.)

 FLI ≥ 60, BARD < 2

111,425

6,664

882056.70

7.56

0.94 (0.91, 0.96)

0.96 (0.93, 0.98)

 FLI ≥ 60, BARD ≥ 2

404,610

38,843

3139790.96

12.37

1.08 (1.07, 1.09)

1.11 (1.10, 1.12)

CVD-specific mortality

 FLI < 60

1,491,740

38,217

11572947.32

3.30

1(Ref.)

1(Ref.)

 FLI ≥ 60, BARD < 2

111,425

1,345

882056.70

1.52

1.00 (0.95, 1.06)

1.12 (1.05, 1.18)

 FLI ≥ 60, BARD ≥ 2

404,610

8,006

3139790.96

2.55

1.08 (1.06, 1.11)

1.11 (1.09, 1.14)

Cancer-specific mortality

 FLI < 60

1,491,740

50,087

11572947.32

4.33

1(Ref.)

1(Ref.)

 FLI ≥ 60, BARD < 2

111,425

2,327

882056.70

2.64

0.96 (0.92, 1.00)

0.90 (0.87, 0.94)

 FLI ≥ 60, BARD ≥ 2

404,610

12,920

3139790.96

4.11

1.18 (1.16, 1.20)

1.17 (1.15, 1.19)

Respiratory disease-related mortality

 FLI < 60

1,491,740

18,445

11572947.32

1.59

1 (Ref.)

1 (Ref.)

 FLI ≥ 60, BARD < 2

111,425

424

882056.70

0.48

0.72 (0.65, 0.79)

0.89 (0.80, 0.98)

 FLI ≥ 60, BARD ≥ 2

404,610

2,865

3139790.96

0.91

0.85 (0.81, 0.88)

0.95 (0.91, 0.99)

Liver disease-related mortality

 FLI < 60

1,491,740

6,343

11572947.32

0.55

1(Ref.)

1(Ref.)

 FLI ≥ 60, BARD < 2

111,425

484

882056.70

0.55

1.29 (1.18, 1.42)

1.08 (0.99, 1.19)

 FLI ≥ 60, BARD ≥ 2

404,610

3,780

3139790.96

1.20

2.51 (2.41, 2.61)

2.38 (2.29, 2.49)

  1. Model 1 was adjusted for age and sex; Model 2 was adjusted for smoking status, alcohol consumption, physical activity, low income, alanine aminotransferase, hypertension, dyslipidemia, Charlson comorbidity index, diabetes complication and diabetes duration in addition to covariates in model 1
  2. PY person year, CVD cardiovascular diseases, FLI fatty liver index