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Table 3 Risk factors of development of carotid plaque during 3-year follow-up

From: Association between the triglyceride-glucose index and carotid plaque incidence: a longitudinal study

Variables

Univariate models

 

Multivariate models

 
 

HR (95%CI)

P value

HR (95%CI)

P value

Gender (male)

1.327 (1.095–1.608)

0.004

1.327 (1.068–1.650)

0.011

Age (years)

1.052 (1.042–1.062)

 < 0.001

1.049 (1.039–1.060)

 < 0.001

SBP (mmHg)

1.014 (1.009–1.020)

 < 0.001

1.004 (0.997–1.012)

0.246

LDL-C (mmol/L)

1.072 (0.946–1.215)

0.275

1.054 (0.917–1.212)

0.456

HDL-C (mmol/L)

0.681 (0.496–0.933)

0.017

0.880 (0.585–1.324)

0.539

History of hyperlipidemia

1.376 (0.959–1.975)

0.083

1.073 (0.737–1.561)

0.713

History of hypertension

1.490 (1.226–1.811)

 < 0.001

1.057 (0.811–1.377)

0.682

History of diabetes

2.207 (1.643–2.966)

 < 0.001

0.717 (0.519–0.991)

0.044

BMI Classification

    

 Underweight (< 18.5)

Ref.

0.558

Ref.

0.144

 Normal (18.6–24.9)

1.551 (0.690–3.484)

0.288

1.207 (0.532–2.741)

0.653

 Overweight (25–29.9)

1.651 (0.730–3.734)

0.228

0.932 (0.401–2.166)

0.869

 Obesity (> = 30)

1.831 (0.735–4.56)

0.194

1.003 (0.388–2.595)

0.995

TyG

    

 Quartile 1

Ref.

 < 0.001

Ref.

0.044

 Quartile 2

1.590 (1.194–2.116)

0.001

1.376 (1.021–1.854)

0.036

 Quartile 3

1.423 (1.059–1.912)

0.019

1.083 (0.779–1.507)

0.634

 Quartile 4

2.026 (1.535–2.675)

 < 0.001

1.437 (1.007–2.052)

0.046

  1. Bold P values indicate significance
  2. SBP systolic blood pressure, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, BMI body mass index
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Cardiovascular Diabetology

ISSN: 1475-2840