Table 2 Associations between weighted gene co-expression network analysis module eigenvalues and incident type 2 diabetes
Modules | Q1 | Q2 (ORs [95% CI]) | Q3 (ORs [95% CI]) | Q4 (ORs [95% CI]) | Ptrend |
|---|---|---|---|---|---|
Blue: TGs, DGs and PCs with a 22:6 fatty acid and other LCFA; number of lipid species = 35 | |||||
1 | 1.03(0.51–2.07) | 1.61(0.81–3.20) | 2.18(1.13–4.22) | 0.012 | |
Red: ether-PCs and ether-PEs with an unsaturated-LCFA; number of lipid species = 16 | |||||
1 | 0.74(0.38–1.44) | 0.99(0.47–2.09) | 1.08(0.52–2.26) | 0.700 | |
Green: ether-PCs with a saturated-LCFA; number of lipid species = 18 | |||||
1 | 1.76(0.93–3.32) | 1.25(0.63–2.48) | 1.21(0.53–2.77) | 0.322 | |
Yellow: SMs with LCFA; number of lipid species = 25 | |||||
1 | 1.64(0.81–3.30) | 1.28(0.62–2.67) | 1.39(0.64–3.02) | 0.457 | |
Pink: TGs with at least one 18:2 FA; number of lipid species = 13 | |||||
1 | 0.88(0.44–1.73) | 0.84(0.42–1.68) | 1.46(0.75–2.84) | 0.121 | |
Green-yellow: DGs with LCFA; number of lipid species = 10 | |||||
1 | 0.66(0.32–1.36) | 0.80(0.38–1.69) | 0.52(0.22–1.27) | 0.709 | |
Black: PEs with a saturated-LCFA and an unsaturated-LCFA; number of lipid species = 14 | |||||
1 | 1.47(0.78–2.77) | 1.64(0.83–3.24) | 1.32(0.62–2.82) | 0.073 | |
Turquoise: TGs containing LCFA with less than 2 double bonds and PCs with LCFA; number of lipid species = 47 | |||||
1 | 0.63(0.32–1.23) | 0.74(0.36–1.52) | 1.03(0.48–2.21) | 0.209 | |
Brown: LPCs and ether LPCs containing LCFA and VLCFA; number of lipid species = 30 | |||||
1 | 0.64(0.33–1.25) | 0.21(0.09–0.47) | 0.55(0.27–1.12) | 0.035 | |