Specific triacylglycerol, diacylglycerol, and lyso-phosphatidylcholine species for the prediction of type 2 diabetes: a ~ 16-year prospective study in Chinese

Table 1 Baseline characteristics of study participants according to glycaemic status on long-term follow-up

	Incident T2D n = 196	Persistent non-T2D n = 196	Missing data (n)	p-value^b
Age (years)	51.7 ± 9.8	52.1 ± 9.8	0	0.719
Male (%)	48.5	48.0	0	1.00
BMI (kg/m²)	25.8 ± 3.4	24.1 ± 2.9	0	< 0.001
Fasting glucose (mmol/l)	5.40 ± 0.55	5.06 ± 0.45	0	< 0.001
2-h glucose (mmol/l)	8.09 ± 1.69	6.51 ± 1.56	0	< 0.001
Prediabetes (%)	60.20	27.55	0	< 0.001
HOMA-IR^a	2.3 (1.5-3.1)	1.6 (1.1-2.2)	1	< 0.001
HOMA-β^a	100.0 (66.5–156.1)	98.7 (72.8–130)	1	0.387
TC (mmol/l)^a	5.40 (4.80–5.90)	5.30 (4.80–5.80)	2	0.454
TG (mmol/l)^a	1.35 (1.00–2.00)	1.00 (0.80–1.43)	2	< 0.001
LDL-C (mmol/l)^a	3.40 (2.90–3.90)	3.40 (2.90–3.80)	5	0.971
HDL-C (mmol/l)^a	1.24 (1.03–1.45)	1.30 (1.16–1.63)	2	< 0.001
TG/HDL ratio	2.48 (1.66–4.17)	1.70 (1.15–2.56)	2	< 0.001
Creatinine (μmol/l)^a	80.0 (67.00–96.00)	79.0 (62.75–94.00)	1	0.232
Hypertension (%)	30.1	21.9	0	0.066
CVD (%)	3.1	0.5	0	0.122

Data are presented as mean ± SD or median (interquartile range)
T2D type 2 diabetes, BMI body mass index, HOMA-IR homeostasis model assessment of insulin resistance, HOMA-β homeostasis model assessment of β-cell function, TC total cholesterol, TG triacylglycerol, LDL-C low-density lipoprotein-cholesterol, HDL-C, high-density lipoprotein cholesterol, TG/HDL ratio triacylglycerol to high-density lipoprotein cholesterol ratio, CVD cardiovascular disease
^aNatural log-transformed before analysis
^bP values of plasma indicators were obtained from independent samples tests or Pearson tests for the binary variables

ISSN: 1475-2840