From: NT-ProBNP and mortality across the spectrum of glucose tolerance in the general US population
NT-ProBNP (pg/ml) | Â | Â | Â | |
---|---|---|---|---|
Variable |  < 100 | 100–299 |  ≥ 300 | Total |
Age (years) | 55.1 (0.2) | 61.8 (0.4) | 66.3 (0.6) | 57.4 (0.2) |
Age category (%) | ||||
 45–59 | 73.2 (1.0) | 42.1 (1.8) | 24.5 (2.4) | 62.5 (1.1) |
 60–79 | 26.8 (1.0) | 57.9 (1.8) | 75.5 (2.4) | 37.5 (1.1) |
Male (%) | 53.0 (1.0) | 26.5 (1.2) | 36.3 (2.8) | 45.5 (0.7) |
Race-ethnicity (%) | ||||
 Non-Hispanic White | 75.3 (1.9) | 81.5 (2.0) | 81.4 (2.8) | 77.2 (1.8) |
 Hispanic | 10.1 (1.7) | 8.1 (1.5) | 7.8 (2.0) | 9.5 (1.6) |
 Non-Hispanic Black | 9.9 (1.0) | 7.3 (1.0) | 9.6 (1.7) | 9.3 (0.9) |
 Other | 4.7 (0.7) | 3.0 (0.7) | 1.2 (0.6) | 4.0 (0.6) |
BMI (kg/m2) | 28.9 (0.1) | 28.1 (0.2) | 28.5 (0.5) | 28.6 (0.1) |
SBP (mmHg) | 127.2 (0.3) | 135.0 (0.8) | 143.6 (1.5) | 130.2 (0.3) |
DBP (mmHg) | 75.6 (0.2) | 72.6 (0.4) | 72.9 (0.8) | 74.7 (0.2) |
Triglycerides (mg/dL) | 156.5 (3.1) | 132.4 (2.6) | 146.1 (5.3) | 150.0 (2.3) |
HbA1c (%) | 5.7 (0.0) | 5.6 (0.0) | 5.7 (0.1) | 5.6 (0.0) |
HDL-C (mg/dL) | 52.3 (0.3) | 58.0 (0.6) | 56.5 (1.2) | 53.9 (0.3) |
AST (U/L) | 25.8 (0.3) | 24.0 (0.5) | 25.5 (0.7) | 25.3 (0.2) |
ALT (U/L) | 27.4 (0.4) | 21.9 (0.6) | 22.5 (1.1) | 25.8 (0.3) |
eGFR (ml/min/1.73 m2) | 91.5 (0.3) | 85.0 (0.6) | 73.2 (1.4) | 88.8 (0.3) |
Total Cholesterol (mg/dl) | 212.1 (0.8) | 209.2 (1.3) | 206.6 (2.7) | 211.0 (0.7) |
Blood pressure (%) | ||||
 Optimal | 24.9 (1.1) | 19.5 (1.3) | 7.8 (1.9) | 22.5 (0.9) |
 Normal | 20.1 (0.9) | 12.7 (1.1) | 8.9 (1.9) | 17.6 (0.7) |
 High-normal | 13.6 (0.6) | 12.2 (1.2) | 10.9 (1.9) | 13.1 (0.5) |
 Hypertension | 41.4 (1.4) | 55.6 (1.6) | 72.3 (2.3) | 46.9 (1.2) |
Education (%) | ||||
 High school or less | 43.0 (1.4) | 49.2 (1.9) | 62.8 (3.9) | 45.8 (1.3) |
 Some college | 29.8 (1.0) | 27.1 (1.7) | 19.9 (2.4) | 28.5 (0.9) |
 College graduate or above | 27.2 (1.4) | 23.7 (1.8) | 17.3 (3.1) | 25.7 (1.2) |
Glycemic category (%) | ||||
 Euglycemic | 70.0 (1.4) | 69.9 (2.1) | 58.6 (2.0) | 69.0 (1.2) |
 Pre-diabetes | 17.7 (1.0) | 16.9 (1.7) | 18.9 (1.7) | 17.6 (0.8) |
 Diabetes | 12.3 (0.7) | 13.1 (1.1) | 22.5 (1.9) | 13.4 (0.6) |
UACR (mg/g, %) | ||||
  < 30 | 92.0 (0.6) | 87.8 (1.3) | 66.1 (2.6) | 89.4 (0.6) |
 30–300 | 7.3 (0.5) | 10.8 (1.2) | 25.3 (2.4) | 9.3 (0.5) |
  > 300 | 0.7 (0.2) | 1.4 (0.3) | 8.6 (1.3) | 1.4 (0.2) |
Cigarette smoke (%) | ||||
 Never | 44.9 (1.2) | 49.6 (1.7) | 42.0 (2.6) | 45.8 (1.0) |
 Former | 34.4 (1.0) | 31.7 (1.7) | 40.2 (2.6) | 34.1 (1.0) |
 Current | 20.7 (0.9) | 18.8 (1.4) | 17.7 (2.1) | 20.1 (0.8) |