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Table 3 Incident diagnosis of cardiovascular outcomes in subgroup after propensity score matching

From: Long-term cardiovascular outcomes of gestational diabetes mellitus: a prospective UK Biobank study

Outcomes

No history of GDM

History of GDM

HRa (95% CI)

(n = 6,900)

(n = 1,380)

Total cardiovascular outcome

399 (6.3%)

108 (8.5%)

1.33 (1.14–1.55)

Coronary artery disease

211 (3.2%)

55 (4.1%)

1.30 (1.05–1.61)

Myocardial infarction

74 (1.1%)

29 (2.2%)

1.69 (1.25–2.30)

Ischemic stroke

50 (0.7%)

16 (1.2%)

1.46 (0.98–2.18)

Peripheral artery disease

25 (0.4%)

13 (0.9%)

2.08 (1.29–3.35)

Heart failure

87 (1.3%)

25 (1.8%)

1.42 (1.03–1.95)

Aortic stenosis

20 (0.3%)

3 (0.2%)

0.86 (0.36–2.02)

Mitral regurgitation

20 (0.3%)

13 (0.9%)

2.92 (1.59–5.38)

Atrial fibrillation/flutter

138 (2.0%)

40 (2.9%)

1.39 (1.09–1.79)

Venous thromboembolism

99 (1.5%)

20 (1.5%)

1.02 (0.73–1.44)

  1. The control group was selected after matching for age, race, BMI, smoking history, alcohol consumption, early menopause, hysterectomy, prevalent morbidities (diabetes, hypertension, dyslipidemia), and medications (aspirin, anti-hypertensives, cholesterol-lowering agent). Data are presented as proportion (%)
  2. aAdjusted for age, race, BMI, smoking, alcohol consumption, early menopause, hysterectomy, prevalent diseases (hypertension, diabetes, or dyslipidemia), and medication (aspirin, anti-hypertensive, and cholesterol-lowering agent) by Cox proportional hazards regression analysis