Table 4 Category free Net Reclassification Index and likelihood ratio test for addition of PGS to prediction model for incident MACE (n = 22,065) and incident diabetes (n = 25,655)
From: Polygenic scores for low lung function and the future risk of adverse health outcomes
| Â | Category free Net Reclassification Index (NRI) | Likelihood ratio (LR) test | ||
|---|---|---|---|---|
| Â | NRI | p-value | LR chi 2 test | p-value |
Incident MACE, addition of FEV1−PGS | 0.10 | 0.995 | 2.21 | 0.1371 |
Incident MACE, addition of FVC-PGS | 0.46 | 0.788 | 1.77 | 0.1837 |
Incident Diabetes, addition of FEV1-PGS | 1.27 | 0.396 | 4.67 | 0.0308 |
Incident Diabetes, addition of FVC-PGS | 4.77 | 0.001 | 18.07 | < 0.001 |