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Table 1 Clinical characteristics

From: Glycemic control is independently associated with rapid progression of coronary atherosclerosis in the absence of a baseline coronary plaque burden: a retrospective case–control study from the PARADIGM registry

Characteristics

Total (n = 402)

Age, years

57.6 ± 10.0

Traditional risk factors, n (%)

 

Advanced age (≥ 60 years)

172 (42.8)

Male

198 (49.3)

Hypertension

173 (43.0)

Diabetes mellitus

52 (12.9)

Metformin use

20 (5.0)

Insulin use

6 (1.5)

Hyperlipidemia

137 (34.1)

Obesity

173 (43.0)

Current smoking

58 (14.4)

At baseline CCTA

 

BMI, kg/m2

24.9 ± 3.2

SBP, mmHg

127.1 ± 18.5

DBP, mmHg

77.2 ± 10.9

Total cholesterol, mg/dL

189.6 ± 41.3

Triglyceride, mg/dL

136.2 ± 75.4

HDL-C, mg/dL

51.7 ± 13.7

LDL-C, mg/dL

116.3 ± 33.8

Creatinine, mg/dL

0.98 ± 0.73

Glucose, mg/dL

105.4 ± 31.9

Hemoglobin A1C, %

6.3 ± 1.3

Statin use, n (%)

121 (30.0)

At follow-up CCTA

 

BMI, kg/m2

25.1 ± 3.3

SBP, mmHg

125.8 ± 17.6

DBP, mmHg

76.3 ± 10.5

Total cholesterol, mg/dL

178.8 ± 38.7*

Triglyceride, mg/dL

135.1 ± 93.7

HDL-C, mg/dL

50.6 ± 13.5*

LDL-C, mg/dL

105.4 ± 31.9*

Creatinine, mg/dL

0.90 ± 0.50*

Glucose, mg/dL

106.7 ± 33.7

Hemoglobin A1C, %

6.3 ± 1.1

Statin use, n (%)

182 (45.3)

Follow-up CCTA findings

 

Newly developed plaque, n (%)

143 (35.6)

RPP, n (%)

17 (4.2)

Plaque volume, mm3

 

Total

12.98 ± 32.71

Fibrous

7.04 ± 19.62

Fibrous-fatty

2.99 ± 10.23

Necrotic core

0.44 ± 2.63

Dense calcium

2.49 ± 8.90

  1. Values are given as mean ± standard deviation or number (%)
  2. *P < 0.05 vs. baseline CCTA in laboratory findings
  3. BMI body mass index, CCTA coronary computed tomography angiography, DBP diastolic blood pressure, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, RPP rapid plaque progression, SBP systolic blood pressure