Diabetes (n = 3281) | No diabetes (n = 3281) | p-value | SMD | |
---|---|---|---|---|
Demographics | ||||
Age (years) | 80 ± 6 | 80 ± 8 | 0.60 | 0.013 |
Women | 1736 (54%) | 1709 (54%) | 0.50 | 0.019 |
Body mass index (kg/m2) | 28 ± 5 | 28 ± 5 | 0.95 | 0.002 |
Body surface area (m2) | 1.78 ± 0.18 | 1.78 ± 0.18 | 0.96 | 0.001 |
Medical history | ||||
Stroke or TIA | 358 (11%) | 342 (11%) | 0.52 | 0.028 |
Myocardial infarction | 523 (16%) | 538 (17%) | 0.61 | 0.019 |
Previous PCI | 772 (24%) | 781 (25%) | 0.79 | 0.009 |
Previous CABG | 486 (15%) | 505 (16%) | 0.51 | 0.025 |
Hypertension | 2710 (85%) | 2705 (85%) | 0.86 | 0.007 |
Dyslipidaemia | 2102 (66%) | 2104 (66%) | 0.96 | 0.002 |
Peripheral vascular disease | 554 (17%) | 547 (17%) | 0.82 | 0.009 |
Coronary artery disease | 1478 (46%) | 1503 (47%) | 0.53 | 0.017 |
Atrial fibrillation | 834 (26%) | 839 (26%) | 0.89 | 0.005 |
Renal failure | 439 (14%) | 403 (13%) | 0.19 | 0.054 |
GFR (ml/min/1.73m2) | 51.4 (37.4–69.0) | 54.1 (40.6–71.4) | < 0.001 | 0.096 |
NYHA ≥ 3 | 751 (40%) | 768 (42%) | 0.14 | 0.054 |
Risk scores | ||||
Logistic EuroSCORE (%) | 15.5 (9.5–23.0) | 14.6 (9.0-23.3) | 0.02 | 0.036 |
STS-PROM (%) | 7.0 (4.1–13.4) | 5.5 (3.3–12.0) | < 0.001 | 0.158 |
EuroSCORE II (%) | 4.6 (2.7–8.2) | 3.7 (2.2–6.4) | < 0.001 | 0.211 |
Medication | ||||
Statin | 456 (72%) | 482 (72%) | 0.73 | 0.024 |
Aspirin | 895 (67%) | 943 (66%) | 0.69 | 0.018 |
Clopidogrel | 457 (47%) | 462 (45%) | 0.22 | 0.061 |
Oral anticoagulation | 505 (35%) | 546 (36%) | 0.39 | 0.036 |
Echocardiographic characteristics | ||||
LVEF (%) | 55 ± 14 | 56 ± 15 | 0.65 | 0.069 |
Max gradient (mmHg) | 76 ± 22 | 77 ± 23 | 0.17 | 0.002 |
Mean gradient (mmHg) | 48 ± 16 | 48 ± 16 | 0.95 | 0.040 |
Aortic valve area (cm2) | 0.67 ± 0.19 | 0.69 ± 0.22 | < 0.001 | 0.118 |
Stroke volume (mL) | 29 ± 8 | 29 ± 7 | 0.61 | 0.052 |
Stroke volume index (mL/m2) | 16 ± 5 | 16 ± 4 | 0.42 | 0.081 |
Device Type | ||||
Balloon-expandable valve | 1671 (53%) | 1661 (52%) | 0.80 | 0.007 |
Third generation valve | 1031 (32%) | 1011 (32%) | 0.59 | 0.016 |