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Table 3 Baseline patient characteristics of the propensity matched population

From: Diabetes mellitus in transfemoral transcatheter aortic valve implantation: a propensity matched analysis

 

Diabetes

(n = 3281)

No diabetes

(n = 3281)

p-value

SMD

Demographics

    

Age (years)

80 ± 6

80 ± 8

0.60

0.013

Women

1736 (54%)

1709 (54%)

0.50

0.019

Body mass index (kg/m2)

28 ± 5

28 ± 5

0.95

0.002

Body surface area (m2)

1.78 ± 0.18

1.78 ± 0.18

0.96

0.001

Medical history

    

Stroke or TIA

358 (11%)

342 (11%)

0.52

0.028

Myocardial infarction

523 (16%)

538 (17%)

0.61

0.019

Previous PCI

772 (24%)

781 (25%)

0.79

0.009

Previous CABG

486 (15%)

505 (16%)

0.51

0.025

Hypertension

2710 (85%)

2705 (85%)

0.86

0.007

Dyslipidaemia

2102 (66%)

2104 (66%)

0.96

0.002

Peripheral vascular disease

554 (17%)

547 (17%)

0.82

0.009

Coronary artery disease

1478 (46%)

1503 (47%)

0.53

0.017

Atrial fibrillation

834 (26%)

839 (26%)

0.89

0.005

Renal failure

439 (14%)

403 (13%)

0.19

0.054

GFR (ml/min/1.73m2)

51.4 (37.4–69.0)

54.1 (40.6–71.4)

< 0.001

0.096

NYHA ≥ 3

751 (40%)

768 (42%)

0.14

0.054

Risk scores

    

Logistic EuroSCORE (%)

15.5 (9.5–23.0)

14.6 (9.0-23.3)

0.02

0.036

STS-PROM (%)

7.0 (4.1–13.4)

5.5 (3.3–12.0)

< 0.001

0.158

EuroSCORE II (%)

4.6 (2.7–8.2)

3.7 (2.2–6.4)

< 0.001

0.211

Medication

    

Statin

456 (72%)

482 (72%)

0.73

0.024

Aspirin

895 (67%)

943 (66%)

0.69

0.018

Clopidogrel

457 (47%)

462 (45%)

0.22

0.061

Oral anticoagulation

505 (35%)

546 (36%)

0.39

0.036

Echocardiographic characteristics

    

LVEF (%)

55 ± 14

56 ± 15

0.65

0.069

Max gradient (mmHg)

76 ± 22

77 ± 23

0.17

0.002

Mean gradient (mmHg)

48 ± 16

48 ± 16

0.95

0.040

Aortic valve area (cm2)

0.67 ± 0.19

0.69 ± 0.22

< 0.001

0.118

Stroke volume (mL)

29 ± 8

29 ± 7

0.61

0.052

Stroke volume index (mL/m2)

16 ± 5

16 ± 4

0.42

0.081

Device Type

    

Balloon-expandable valve

1671 (53%)

1661 (52%)

0.80

0.007

Third generation valve

1031 (32%)

1011 (32%)

0.59

0.016

  1. Values are median (interquartile range), n (%), or mean ± standard devation. TIA: transient ischemic attack; PCI: percutaneous coronary intervention; CABG: coronary artery bypass grafting; GFR: glomerular filtration rate; NYHA: New York Heart Association functional class; EuroSCORE: European System for Cardiac Operative Risk Evaluation; LVEF: Left Ventricular Ejection Fraction; STS-PROM: Society of Thoracic Surgeons Predicted Risk of Mortality; SMD: Standardized Mean Difference; Stroke volume index: as indexed to body surface area