Table 1 Descriptive analysis of clinical variables by group
Variable | Myocardial Dysfunction (n 154) | Control (n 150) | p value |
|---|---|---|---|
Sex (men) | 72 (46.8%) | 69 (46.0%) | 0.987 |
Age (years) | 61.0 (11.7) | 60.6 (11.1) | 0.756 |
Diabetes duration (years) | 35.1 (14.9) | 30.1 (15.5) | 0.005 |
EF (%) | 55.8 (7.58) | 58.6 (5.24) | < 0.001 |
E/e´ Cocient | < 0.001 | ||
E/e´ <8 | 8 (5.19%) | 92 (61.3%) | |
E/e´ 8–12 | 67 (43.5%) | 58 (38.7%) | |
E/e´ >12 | 79 (51.3%) | 0 (0.00%) | |
LAV (ml/m2) | 34.1 (7.67) | 28.9 (5.52) | < 0.001 |
Diastolic HF | < 0.001 | ||
No | 8 (5.19%) | 150 (100%) | |
Yes | 146 (94.8%) | 0 (0.00%) | |
Systolic HF | < 0.001 | ||
No | 136 (88.3%) | 150 (100%) | |
Yes | 18 (11.7%) | 0 (0.00%) | |
Height (m) | 1.71 (0.09) | 1.73 (0.10) | 0.037 |
Weight (Kg) | 76.4 (15.1) | 75.1 (13.7) | 0.422 |
BMI (Kg/m2) | 26.1 (3.93) | 25.0 (3.66) | 0.013 |
Diastolic BP (mmHg) | 73.5 (11.2) | 71.4 (9.53) | 0.073 |
Systolic BP (mmHg) | 143 (17.7) | 136 (17.9) | 0.002 |
Statin use | 0.039 | ||
No | 52 (33.8%) | 69 (46.0%) | |
Yes | 102 (66.2%) | 81 (54.0%) | |
Antihypertensive use | < 0.001 | ||
No | 29 (19.8%) | 59 (39.3%) | |
Yes | 125 (81.2%) | 91 (60.7%) | |
Smoking habit | 0.140 | ||
Never smoker | 51 (33.1%) | 61 (40.7%) | |
Current smoker | 25 (16.2%) | 30 (20.0%) | |
Ex-smoker | 78 (50.6%) | 59 (39.3%) | |
NTproBNP (pg/mL) | 352 [163;591] | 249 [116;449] | < 0.001 |
MRproANP (pmol/L) | 100 [69.2;144] | 82.3 [56.4;112] | < 0.001 |
HbA1c value (%) | 8.19 (1.11) | 8.01 (1.20) | 0.178 |
Total cholesterol (mmol/L) | 4.77 (0.99) | 4.72 (0.93) | 0.620 |
LDL cholesterol (mmol/L) | 2.44 (0.70) | 2.44 (0.80) | 0.997 |
Triglycerides (mmol/L) | 1.12 (0.78) | 1.07 (0.60) | 0.595 |
24 h albumin in urine (mg/24 h) | 309 (1587) | 18.0 (26.0) | 0.026 |
eGFR value (mL/min/1.73m2) | 75.4 (26.2) | 83.7 (21.0) | 0.003 |
Albuminuria status | < 0.001 | ||
Normoalbuminuria | 73 (47.4%) | 110 (73.3%) | |
Microalbuminuria | 42 (27.3%) | 35 (23.3%) | |
Macroalbuminuria | 39 (25.3%) | 5 (3.33%) | |
Retinopathy status global (worst eye) | < 0.001 | ||
Normal | 37 (24.2%) | 55 (36.7%) | |
Simplex retinopathy | 63 (41.2%) | 79 (52.7%) | |
Proliferative retinopathy | 53 (34.6%) | 16 (10.7%) |