TyGIS: improved triglyceride-glucose index for the assessment of insulin sensitivity during pregnancy

Table 2 OGTT parameters in women divided for glucose tolerance or for body mass index (BMI)

OGTT parameter	NGT	Non-NGT	Lean	Overweight/Obese
N	72	12	23	61
Insulin sensitivity
PREDIM (mg kg min⁻¹)	5.89 [2.34]	2.89 [1.01]^d	6.49 [3.57]	4.88 [2.54]^g
Insulin secretion
BSR (pmol min^–1 m^–2)	84.12 [39.63]	136.20 [48.33]^b	77.84 [36.27]	99.68 [47.85]^f
TIS (nmol m^–2)	46.80 [19.42]	69.06 [16.96]^c	44.92 [16.85]	54.16 [22.39]
Beta-cell function
G-sens (pmol min^–1 m^–2 mM^–1)	140.24 [81.51]	89.92 [31.27]^d	154.55 [106.32]	122.33 [59.01]
R-sens (pmol m^–2 mM^–1)	1028.41 [1313.86]	706.17 [705.18]	716.84 [1727.23]	1028.36 [974.72]
PFR (unitless)	1.35 [0.49]	1.42 [0.71]	1.35 [0.40]	1.37 [0.61]

Data are reported as median [IQR]. The values of the parameters refer to visit 2. Accordingly, stratification in NGT and non-NGT, as well as Lean and Obese/Overweight, refers to visit 2
NGT normal glucose tolerance, Lean BMI < 25 kg/m², Overweight/Obese otherwise
^ap < 0.05 for NGT and Non-NGT
^bp < 0.01 for NGT and Non-NGT
^cp < 0.001 for NGT and Non-NGT
^dp < 0.0001 for NGT and Non-NGT
^ep < 0.05 for Lean and Overweight/Obese
^fp < 0.01 for Lean and Overweight/Obese
^gp < 0.001 for Lean and Overweight/Obese
^hp < 0.0001 for Lean and Overweight/Obese

ISSN: 1475-2840