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Table 1 Feature values in pregnant women divided for glucose tolerance or for body mass index (BMI)

From: TyGIS: improved triglyceride-glucose index for the assessment of insulin sensitivity during pregnancy

Feature

NGT

Non-NGT

Lean

Overweight/Obese

N

72

12

23

61

TyG index (unitless)

8.84 ± 0.36

9.12 ± 0.42a

8.69 ± 0.35

8.96 ± 0.37f

Age (years)

30.1 ± 4.9

32.8 ± 6.0

30.3 ± 4.8

30.5 ± 5.3

Pre-pregn. body weight (kg)

63.50 [13.50]

76.00 [33.85]a

59.00 [8.75]

70.00 [19.13]h

Body weight (kg)

72.95 [15.60]

81.20 [33.00]a

62.00 [7.38]

77.00 [14.64]h

Height (m)

1.66 ± 0.06

1.63 ± 0.06

1.67 ± 0.07

1.65 ± 0.06

BMI (kg/m2)

26.51 [4.35]

29.80 [11.51]d

22.46 [1.68]

28.07 [5.54]h

BSA (m2)

1.88 [0.25]

2.02 [0.35]

1.75 [0.13]

1.93 [0.23]h

LBM (%)

48.81 ± 5.42

51.75 ± 7.71

45.90 ± 4.64

50.49 ± 5.78

Total pregnancy no. (counts)

2.00 [2.00]

2.00 [2.00]

2.00 [2.00]

2.00 [2.00]

Parity (counts)

0.00 [1.00]

0.00 [0.50]

0.00 [1.00]

0.00 [1.00]

Multiple pregn. (counts, perc.)

8 (11.1%)

0 (0.0%)

1 (4.3%)

7 (11.5%)

Week of gestation (weeks)

26.00 [1.86]

25.86 [1.28]

25.57 [1.39]

26.14 [1.85]

GDM (counts, perc.)

0 (0.0%)

9 (75.0%)d

1 (4.3%)

8 (13.1%)

Fasting glucose (mmol/L)

4.27 [0.56]

4.91 [0.56]b

4.16 [0.49]

4.44 [0.72]e

Fasting insulin (pmol/L)

51.30 [44.49]

86.97 [64.17]a

45.36 [48.38]

57.06 [47.72]e

Fasting C-peptide (nmol/L)

0.63 [0.28]

1.03 [0.46]b

0.60 [0.26]

0.73 [0.40]f

Hb (g/L)

112.75 ± 9.89

118.17 ± 10.68

113.65 ± 11.83

113.48 ± 9.51

HbA1c (%)

4.79 ± 0.30

5.3 ± 0.35c

4.71 ± 0.34

4.92 ± 0.34e

Platelet count (U/L)

242.50 [54.50]

279.50 [58.50]

243.00 [37.00]

250.00 [80.00]

C-reactive protein (mg/L)

0.40 [0.58]

0.77 [0.47]

0.29 [0.58]

0.47 [0.61]

Albumin (g/L)

39.68 ± 2.32

39.93 ± 2.47

39.73 ± 2.55

39.71 ± 2.26

Creatinine (µmol/L)

43.77 [8.84]

41.56 [11.94]

42.44 [10.17]

43.33 [8.84]

Triglycerides (mmol/L)

1.99 [0.95]

2.36 [1.08]

1.85 [0.80]

2.10 [1.05]f

Cholesterol (mmol/L)

6.53 ± 1.27

6.28 ± 1.22

6.69 ± 1.38

6.42 ± 1.21

HDL (mmol/L)

1.89 [0.80]

1.70 [0.56]

2.07 [0.87]

1.84 [0.85]

LDL (mmol/L)

3.54 ± 1.10

3.37 ± 0.99

3.76 ± 1.22

3.42 ± 1.01

ASAT (U/L)

20.00 [8.00]

20.50 [6.00]

22.00 [8.00]

20.00 [7.00]

ALAT (U/L)

14.00 [6.75]

15.50 [14.00]

14.00 [5.00]

14.00 [10.00]

GGT (U/L)

8.00 [4.00]

11.50 [21.00]

9.00 [4.00]

8.00 [5.50]

  1. Data for continuous variables are reported as mean ± SD or median [IQR] as appropriate, and as counts and percentages for categorical variables. Except for pre-pregnancy body weight, the values of all anthropometric and clinical features refer to visit 2. Accordingly, stratification in NGT and non-NGT, as well as Lean and Obese/Overweight, refers to visit 2
  2. NGT normal glucose tolerance, Lean BMI < 25 kg/m2, Overweight/Obese otherwise
  3. ap < 0.05 for NGT and Non-NGT
  4. bp < 0.01 for NGT and Non-NGT
  5. cp < 0.001 for NGT and Non-NGT
  6. dp < 0.0001 for NGT and Non-NGT
  7. ep < 0.05 for Lean and Overweight/Obese
  8. fp < 0.01 for Lean and Overweight/Obese
  9. gp < 0.001 for Lean and Overweight/Obese
  10. hp < 0.0001 for Lean and Overweight/Obese
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Cardiovascular Diabetology

ISSN: 1475-2840