Skip to main content

Table 4 Discrimination and reclassification performance of the addition of circulating TSP2 level in predicting HHF in diabetes

From: Prospective associations of circulating thrombospondin-2 level with heart failure hospitalization, left ventricular remodeling and diastolic function in type 2 diabetes

 

Clinical model without serum TSP2 level

Clinical model with

serum TSP2 level

p-value

c-statistics (95% CI)

0.79 (0.78–0.81)

0.81 (0.79–0.83)

0.003

NRI (95% CI)

 

0.33 (0.26–0.41)

< 0.001

IDI (95% CI)

 

0.02 (0.01–0.03)

< 0.001

  1. Clinical model included age, sex, duration of diabetes, ever-smoker, BMI, hypertension, dyslipidemia, atrial fibrillation, CVD, HbA1c, presence of CKD, albuminuria, and serum hsCRP levels at baseline
  2. TSP2, thrombospondin-2; HHF, hospitalization for heart failure; CI, confidence interval; NRI, net reclassification index; IDI, integrated discrimination index; BMI, body mass index; CVD, cardiovascular disease; HbA1c, glycated hemoglobin; CKD, chronic kidney disease; hsCRP, high-sensitivity C-reactive protein
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840