Table 3 Subgroup analyses for the joint associations of metabolic status and physical activity with incident atrial fibrillation risk*
| Â | Sex | Age | ||||||
|---|---|---|---|---|---|---|---|---|
Male | Female | < 65 years | ≥ 65 years | |||||
Metabolic status & PA | No. of cases/No. of total participants | HR (95% CI), p-value | No. of cases/No. of total participants | HR (95% CI), p-value | No. of cases/No. of total participants | HR (95% CI), p-value | No. of cases/No. of total participants | HR (95% CI), p-value |
MUO & No MVPA | 439/5,643 | Ref | 219/5,021 | Ref | 415/8,668 | Ref | 243/1,996 | Ref |
MUO & Low PA | 569/8,133 | 0.97 (0.86, 1.10), p = 0.64 | 232/7,561 | 0.78 (0.65, 0.94), p < 0.01 | 494/12,834 | 0.89 (0.78, 1.01), p = 0.08 | 307/2,860 | 0.92 (0.78, 1.09), p = 0.34 |
MUO & Medium PA | 294/4,481 | 0.90 (0.78, 1.05), p = 0.18 | 118/4,120 | 0.70 (0.56, 0.88), p < 0.01 | 255/6,875 | 0.85 (0.72, 0.99), p = 0.04 | 157/1,726 | 0.77 (0.63, 0.95), p = 0.01 |
MUO & High PA | 721/11,628 | 0.85 (0.75, 0.96), p = 0.01 | 312/8,040 | 0.89 (0.75, 1.07), p = 0.21 | 633/15,245 | 0.89 (0.79, 1.02), p = 0.08 | 400/4,423 | 0.77 (0.65, 0.91), p < 0.01 |
MHO & No MVPA | 29/1,079 | 0.56 (0.39, 0.82), p < 0.01 | 28/1,857 | 0.62 (0.42, 0.92), p = 0.02 | 48/2,777 | 0.50 (0.37, 0.67), p < 0.01 | 9/159 | 0.52 (0.27 1.01), p = 0.05 |
MHO & Low PA | 48/1,785 | 0.59 (0.44, 0.80), p < 0.01 | 38/3,248 | 0.52 (0.37, 0.74), p < 0.01 | 65/4,710 | 0.44 (0.34, 0.57), p < 0.01 | 21/323 | 0.64 (0.41, 1.00), p = 0.05 |
MHO & Medium PA | 23/1,034 | 0.52 (0.34, 0.79), p < 0.01 | 21/1,682 | 0.53 (0.34, 0.83), p < 0.01 | 36/2,522 | 0.45 (0.32, 0.63), p < 0.01 | 8/194 | 0.40 (0.20, 0.81), p = 0.01 |
MHO & High PA | 84/2,878 | 0.63 (0.50, 0.80), p < 0.01 | 49/3,298 | 0.56 (0.41, 0.77), p < 0.01 | 99/5,651 | 0.49(0.39, 0.61), p < 0.01 | 34/525 | 0.59 (0.41, 0.84), p < 0.01 |